Fluorine in PDB 6ode: Crystal Structure of Mycobacterium Tuberculosis Proteasome in Complex with Phenylimidazole-Based Inhibitor B6
Enzymatic activity of Crystal Structure of Mycobacterium Tuberculosis Proteasome in Complex with Phenylimidazole-Based Inhibitor B6
All present enzymatic activity of Crystal Structure of Mycobacterium Tuberculosis Proteasome in Complex with Phenylimidazole-Based Inhibitor B6:
3.4.25.1;
3.4.25.1;
Protein crystallography data
The structure of Crystal Structure of Mycobacterium Tuberculosis Proteasome in Complex with Phenylimidazole-Based Inhibitor B6, PDB code: 6ode
was solved by
H.C.Hsu,
H.Li,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
| Resolution Low / High (Å) | 53.97 / 2.90 |
| Space group | P 1 21 1 |
| Cell size a, b, c (Å), α, β, γ (°) | 120.603, 198.380, 166.513, 90.00, 103.10, 90.00 |
| R / Rfree (%) | 19.7 / 24.7 |
Fluorine Binding Sites:
Pages:
>>> Page 1 <<< Page 2, Binding sites: 11 - 14;Binding sites:
The binding sites of Fluorine atom in the Crystal Structure of Mycobacterium Tuberculosis Proteasome in Complex with Phenylimidazole-Based Inhibitor B6 (pdb code 6ode). This binding sites where shown within 5.0 Angstroms radius around Fluorine atom.In total 14 binding sites of Fluorine where determined in the Crystal Structure of Mycobacterium Tuberculosis Proteasome in Complex with Phenylimidazole-Based Inhibitor B6, PDB code: 6ode:
Jump to Fluorine binding site number: 1; 2; 3; 4; 5; 6; 7; 8; 9; 10;
Fluorine binding site 1 out of 14 in 6ode
Go back to
Fluorine Binding Sites List in 6ode
Fluorine binding site 1 out
of 14 in the Crystal Structure of Mycobacterium Tuberculosis Proteasome in Complex with Phenylimidazole-Based Inhibitor B6
Mono view
Stereo pair view
Mono view
Stereo pair view
A full contact list of Fluorine with other atoms in the F binding
site number 1 of Crystal Structure of Mycobacterium Tuberculosis Proteasome in Complex with Phenylimidazole-Based Inhibitor B6 within 5.0Å range:
|
Fluorine binding site 2 out of 14 in 6ode
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Fluorine Binding Sites List in 6ode
Fluorine binding site 2 out
of 14 in the Crystal Structure of Mycobacterium Tuberculosis Proteasome in Complex with Phenylimidazole-Based Inhibitor B6
Mono view
Stereo pair view
Mono view
Stereo pair view
A full contact list of Fluorine with other atoms in the F binding
site number 2 of Crystal Structure of Mycobacterium Tuberculosis Proteasome in Complex with Phenylimidazole-Based Inhibitor B6 within 5.0Å range:
|
Fluorine binding site 3 out of 14 in 6ode
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Fluorine Binding Sites List in 6ode
Fluorine binding site 3 out
of 14 in the Crystal Structure of Mycobacterium Tuberculosis Proteasome in Complex with Phenylimidazole-Based Inhibitor B6
Mono view
Stereo pair view
Mono view
Stereo pair view
A full contact list of Fluorine with other atoms in the F binding
site number 3 of Crystal Structure of Mycobacterium Tuberculosis Proteasome in Complex with Phenylimidazole-Based Inhibitor B6 within 5.0Å range:
|
Fluorine binding site 4 out of 14 in 6ode
Go back to
Fluorine Binding Sites List in 6ode
Fluorine binding site 4 out
of 14 in the Crystal Structure of Mycobacterium Tuberculosis Proteasome in Complex with Phenylimidazole-Based Inhibitor B6
Mono view
Stereo pair view
Mono view
Stereo pair view
A full contact list of Fluorine with other atoms in the F binding
site number 4 of Crystal Structure of Mycobacterium Tuberculosis Proteasome in Complex with Phenylimidazole-Based Inhibitor B6 within 5.0Å range:
|
Fluorine binding site 5 out of 14 in 6ode
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Fluorine Binding Sites List in 6ode
Fluorine binding site 5 out
of 14 in the Crystal Structure of Mycobacterium Tuberculosis Proteasome in Complex with Phenylimidazole-Based Inhibitor B6
Mono view
Stereo pair view
Mono view
Stereo pair view
A full contact list of Fluorine with other atoms in the F binding
site number 5 of Crystal Structure of Mycobacterium Tuberculosis Proteasome in Complex with Phenylimidazole-Based Inhibitor B6 within 5.0Å range:
|
Fluorine binding site 6 out of 14 in 6ode
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Fluorine Binding Sites List in 6ode
Fluorine binding site 6 out
of 14 in the Crystal Structure of Mycobacterium Tuberculosis Proteasome in Complex with Phenylimidazole-Based Inhibitor B6
Mono view
Stereo pair view
Mono view
Stereo pair view
A full contact list of Fluorine with other atoms in the F binding
site number 6 of Crystal Structure of Mycobacterium Tuberculosis Proteasome in Complex with Phenylimidazole-Based Inhibitor B6 within 5.0Å range:
|
Fluorine binding site 7 out of 14 in 6ode
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Fluorine Binding Sites List in 6ode
Fluorine binding site 7 out
of 14 in the Crystal Structure of Mycobacterium Tuberculosis Proteasome in Complex with Phenylimidazole-Based Inhibitor B6
Mono view
Stereo pair view
Mono view
Stereo pair view
A full contact list of Fluorine with other atoms in the F binding
site number 7 of Crystal Structure of Mycobacterium Tuberculosis Proteasome in Complex with Phenylimidazole-Based Inhibitor B6 within 5.0Å range:
|
Fluorine binding site 8 out of 14 in 6ode
Go back to
Fluorine Binding Sites List in 6ode
Fluorine binding site 8 out
of 14 in the Crystal Structure of Mycobacterium Tuberculosis Proteasome in Complex with Phenylimidazole-Based Inhibitor B6
Mono view
Stereo pair view
Mono view
Stereo pair view
A full contact list of Fluorine with other atoms in the F binding
site number 8 of Crystal Structure of Mycobacterium Tuberculosis Proteasome in Complex with Phenylimidazole-Based Inhibitor B6 within 5.0Å range:
|
Fluorine binding site 9 out of 14 in 6ode
Go back to
Fluorine Binding Sites List in 6ode
Fluorine binding site 9 out
of 14 in the Crystal Structure of Mycobacterium Tuberculosis Proteasome in Complex with Phenylimidazole-Based Inhibitor B6
Mono view
Stereo pair view
Mono view
Stereo pair view
A full contact list of Fluorine with other atoms in the F binding
site number 9 of Crystal Structure of Mycobacterium Tuberculosis Proteasome in Complex with Phenylimidazole-Based Inhibitor B6 within 5.0Å range:
|
Fluorine binding site 10 out of 14 in 6ode
Go back to
Fluorine Binding Sites List in 6ode
Fluorine binding site 10 out
of 14 in the Crystal Structure of Mycobacterium Tuberculosis Proteasome in Complex with Phenylimidazole-Based Inhibitor B6
Mono view
Stereo pair view
Mono view
Stereo pair view
A full contact list of Fluorine with other atoms in the F binding
site number 10 of Crystal Structure of Mycobacterium Tuberculosis Proteasome in Complex with Phenylimidazole-Based Inhibitor B6 within 5.0Å range:
|
Reference:
W.Zhan,
H.C.Hsu,
T.Morgan,
T.Ouellette,
K.Burns-Huang,
R.Hara,
A.G.Wright,
T.Imaeda,
R.Okamoto,
K.Sato,
M.Michino,
M.Ramjee,
K.Aso,
P.T.Meinke,
M.Foley,
C.F.Nathan,
H.Li,
G.Lin.
Selective Phenylimidazole-Based Inhibitors of Themycobacterium Tuberculosisproteasome. J.Med.Chem. V. 62 9246 2019.
ISSN: ISSN 0022-2623
PubMed: 31560200
DOI: 10.1021/ACS.JMEDCHEM.9B01187
Page generated: Sun Dec 13 13:02:00 2020
ISSN: ISSN 0022-2623
PubMed: 31560200
DOI: 10.1021/ACS.JMEDCHEM.9B01187
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