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Fluorine in PDB 6oim: Crystal Structure of Human Kras G12C Covalently Bound to Amg 510Protein crystallography data
The structure of Crystal Structure of Human Kras G12C Covalently Bound to Amg 510, PDB code: 6oim
was solved by
C.Mohr,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Other elements in 6oim:
The structure of Crystal Structure of Human Kras G12C Covalently Bound to Amg 510 also contains other interesting chemical elements:
Fluorine Binding Sites:
The binding sites of Fluorine atom in the Crystal Structure of Human Kras G12C Covalently Bound to Amg 510
(pdb code 6oim). This binding sites where shown within
5.0 Angstroms radius around Fluorine atom.
In total 2 binding sites of Fluorine where determined in the Crystal Structure of Human Kras G12C Covalently Bound to Amg 510, PDB code: 6oim: Jump to Fluorine binding site number: 1; 2; Fluorine binding site 1 out of 2 in 6oimGo back to Fluorine Binding Sites List in 6oim
Fluorine binding site 1 out
of 2 in the Crystal Structure of Human Kras G12C Covalently Bound to Amg 510
Mono view Stereo pair view
Fluorine binding site 2 out of 2 in 6oimGo back to Fluorine Binding Sites List in 6oim
Fluorine binding site 2 out
of 2 in the Crystal Structure of Human Kras G12C Covalently Bound to Amg 510
Mono view Stereo pair view
Reference:
J.Canon,
K.Rex,
A.Y.Saiki,
C.Mohr,
K.Cooke,
D.Bagal,
K.Gaida,
T.Holt,
C.G.Knutson,
N.Koppada,
B.A.Lanman,
J.Werner,
A.S.Rapaport,
T.San Miguel,
R.Ortiz,
T.Osgood,
J.R.Sun,
X.Zhu,
J.D.Mccarter,
L.P.Volak,
B.E.Houk,
M.G.Fakih,
B.H.O'neil,
T.J.Price,
G.S.Falchook,
J.Desai,
J.Kuo,
R.Govindan,
D.S.Hong,
W.Ouyang,
H.Henary,
T.Arvedson,
V.J.Cee,
J.R.Lipford.
The Clinical Kras(G12C) Inhibitor Amg 510 Drives Anti-Tumour Immunity. Nature V. 575 217 2019.
Page generated: Sun Dec 13 13:02:21 2020
ISSN: ESSN 1476-4687 PubMed: 31666701 DOI: 10.1038/S41586-019-1694-1 |
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