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Atomistry » Fluorine » PDB 6onv-6p3p » 6oph | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Atomistry » Fluorine » PDB 6onv-6p3p » 6oph » |
Fluorine in PDB 6oph: Phosphorylated ERK2 with Gdc-0994Enzymatic activity of Phosphorylated ERK2 with Gdc-0994
All present enzymatic activity of Phosphorylated ERK2 with Gdc-0994:
2.7.11.24; Protein crystallography data
The structure of Phosphorylated ERK2 with Gdc-0994, PDB code: 6oph
was solved by
G.P.Vigers,
D.Smith,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Other elements in 6oph:
The structure of Phosphorylated ERK2 with Gdc-0994 also contains other interesting chemical elements:
Fluorine Binding Sites:
The binding sites of Fluorine atom in the Phosphorylated ERK2 with Gdc-0994
(pdb code 6oph). This binding sites where shown within
5.0 Angstroms radius around Fluorine atom.
In total only one binding site of Fluorine was determined in the Phosphorylated ERK2 with Gdc-0994, PDB code: 6oph: Fluorine binding site 1 out of 1 in 6ophGo back to Fluorine Binding Sites List in 6oph
Fluorine binding site 1 out
of 1 in the Phosphorylated ERK2 with Gdc-0994
Mono view Stereo pair view
Reference:
L.M.Pegram,
J.C.Liddle,
Y.Xiao,
M.Hoh,
J.Rudolph,
D.B.Iverson,
G.P.Vigers,
D.Smith,
H.Zhang,
W.Wang,
J.G.Moffat,
N.G.Ahn.
Activation Loop Dynamics Are Controlled By Conformation-Selective Inhibitors of ERK2. Proc.Natl.Acad.Sci.Usa V. 116 15463 2019.
Page generated: Thu Aug 1 23:52:09 2024
ISSN: ESSN 1091-6490 PubMed: 31311868 DOI: 10.1073/PNAS.1906824116 |
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