Fluorine in PDB 6p7g: The Co-Crystal Structure of Braf(V600E) with PHI1
Enzymatic activity of The Co-Crystal Structure of Braf(V600E) with PHI1
All present enzymatic activity of The Co-Crystal Structure of Braf(V600E) with PHI1:
2.7.11.1;
Protein crystallography data
The structure of The Co-Crystal Structure of Braf(V600E) with PHI1, PDB code: 6p7g
was solved by
B.Agianian,
E.Gavathiotis,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Resolution Low / High (Å)
|
82.45 /
2.65
|
Space group
|
P 21 21 21
|
Cell size a, b, c (Å), α, β, γ (°)
|
95.780,
108.790,
126.380,
90.00,
90.00,
90.00
|
R / Rfree (%)
|
24.8 /
27.9
|
Fluorine Binding Sites:
Pages:
>>> Page 1 <<<
Page 2, Binding sites: 11 -
12;
Binding sites:
The binding sites of Fluorine atom in the The Co-Crystal Structure of Braf(V600E) with PHI1
(pdb code 6p7g). This binding sites where shown within
5.0 Angstroms radius around Fluorine atom.
In total 12 binding sites of Fluorine where determined in the
The Co-Crystal Structure of Braf(V600E) with PHI1, PDB code: 6p7g:
Jump to Fluorine binding site number:
1;
2;
3;
4;
5;
6;
7;
8;
9;
10;
Fluorine binding site 1 out
of 12 in 6p7g
Go back to
Fluorine Binding Sites List in 6p7g
Fluorine binding site 1 out
of 12 in the The Co-Crystal Structure of Braf(V600E) with PHI1
Mono view
Stereo pair view
|
A full contact list of Fluorine with other atoms in the F binding
site number 1 of The Co-Crystal Structure of Braf(V600E) with PHI1 within 5.0Å range:
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
A:F801
b:27.1
occ:1.00
|
F1
|
A:E7M801
|
0.0
|
27.1
|
1.0
|
C20
|
A:E7M801
|
1.3
|
28.0
|
1.0
|
F3
|
A:E7M801
|
2.1
|
26.5
|
1.0
|
F2
|
A:E7M801
|
2.2
|
29.2
|
1.0
|
C19
|
A:E7M801
|
2.3
|
28.6
|
1.0
|
CD2
|
A:HIS574
|
3.0
|
28.3
|
1.0
|
C21
|
A:E7M801
|
3.1
|
31.7
|
1.0
|
NE2
|
A:HIS574
|
3.1
|
27.3
|
1.0
|
C24
|
A:E7M801
|
3.1
|
35.0
|
1.0
|
C18
|
A:E7M801
|
3.3
|
27.0
|
1.0
|
CA
|
A:GLY593
|
3.9
|
31.8
|
1.0
|
C
|
A:GLY593
|
3.9
|
32.9
|
1.0
|
CG
|
A:HIS574
|
4.0
|
27.9
|
1.0
|
O
|
A:GLY593
|
4.0
|
34.0
|
1.0
|
CG2
|
A:ILE592
|
4.0
|
32.7
|
1.0
|
CE1
|
A:HIS574
|
4.1
|
26.5
|
1.0
|
CD1
|
A:LEU567
|
4.1
|
28.1
|
1.0
|
N
|
A:GLY593
|
4.3
|
31.1
|
1.0
|
C22
|
A:E7M801
|
4.3
|
29.6
|
1.0
|
N
|
A:ASP594
|
4.5
|
34.8
|
1.0
|
N5
|
A:E7M801
|
4.5
|
39.5
|
1.0
|
ND1
|
A:HIS574
|
4.5
|
25.9
|
1.0
|
C17
|
A:E7M801
|
4.5
|
27.3
|
1.0
|
C
|
A:ILE592
|
4.6
|
30.6
|
1.0
|
O
|
A:ILE592
|
4.7
|
31.2
|
1.0
|
CB
|
A:HIS574
|
4.9
|
29.7
|
1.0
|
C23
|
A:E7M801
|
4.9
|
27.9
|
1.0
|
|
Fluorine binding site 2 out
of 12 in 6p7g
Go back to
Fluorine Binding Sites List in 6p7g
Fluorine binding site 2 out
of 12 in the The Co-Crystal Structure of Braf(V600E) with PHI1
Mono view
Stereo pair view
|
A full contact list of Fluorine with other atoms in the F binding
site number 2 of The Co-Crystal Structure of Braf(V600E) with PHI1 within 5.0Å range:
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
A:F801
b:29.2
occ:1.00
|
F2
|
A:E7M801
|
0.0
|
29.2
|
1.0
|
C20
|
A:E7M801
|
1.4
|
28.0
|
1.0
|
F3
|
A:E7M801
|
2.1
|
26.5
|
1.0
|
F1
|
A:E7M801
|
2.2
|
27.1
|
1.0
|
C19
|
A:E7M801
|
2.4
|
28.6
|
1.0
|
C18
|
A:E7M801
|
2.8
|
27.0
|
1.0
|
C21
|
A:E7M801
|
3.7
|
31.7
|
1.0
|
CG2
|
A:ILE513
|
3.7
|
28.6
|
1.0
|
CA
|
A:GLY593
|
4.0
|
31.8
|
1.0
|
CD2
|
A:LEU505
|
4.1
|
29.8
|
1.0
|
O
|
A:ILE592
|
4.1
|
31.2
|
1.0
|
C17
|
A:E7M801
|
4.1
|
27.3
|
1.0
|
C24
|
A:E7M801
|
4.3
|
35.0
|
1.0
|
O1
|
A:E7M801
|
4.6
|
31.5
|
1.0
|
C
|
A:ILE592
|
4.6
|
30.6
|
1.0
|
N
|
A:GLY593
|
4.6
|
31.1
|
1.0
|
C
|
A:GLY593
|
4.7
|
32.9
|
1.0
|
CD2
|
A:LEU567
|
4.7
|
29.0
|
1.0
|
C22
|
A:E7M801
|
4.8
|
29.6
|
1.0
|
CD1
|
A:LEU567
|
4.8
|
28.1
|
1.0
|
C23
|
A:E7M801
|
5.0
|
27.9
|
1.0
|
|
Fluorine binding site 3 out
of 12 in 6p7g
Go back to
Fluorine Binding Sites List in 6p7g
Fluorine binding site 3 out
of 12 in the The Co-Crystal Structure of Braf(V600E) with PHI1
Mono view
Stereo pair view
|
A full contact list of Fluorine with other atoms in the F binding
site number 3 of The Co-Crystal Structure of Braf(V600E) with PHI1 within 5.0Å range:
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
A:F801
b:26.5
occ:1.00
|
F3
|
A:E7M801
|
0.0
|
26.5
|
1.0
|
C20
|
A:E7M801
|
1.3
|
28.0
|
1.0
|
F1
|
A:E7M801
|
2.1
|
27.1
|
1.0
|
F2
|
A:E7M801
|
2.1
|
29.2
|
1.0
|
C19
|
A:E7M801
|
2.3
|
28.6
|
1.0
|
C24
|
A:E7M801
|
2.8
|
35.0
|
1.0
|
C21
|
A:E7M801
|
2.9
|
31.7
|
1.0
|
C18
|
A:E7M801
|
3.5
|
27.0
|
1.0
|
CD2
|
A:LEU567
|
3.9
|
29.0
|
1.0
|
CD1
|
A:LEU567
|
4.0
|
28.1
|
1.0
|
N5
|
A:E7M801
|
4.1
|
39.5
|
1.0
|
CG2
|
A:ILE572
|
4.2
|
36.1
|
1.0
|
C22
|
A:E7M801
|
4.2
|
29.6
|
1.0
|
CG
|
A:LEU567
|
4.6
|
28.4
|
1.0
|
CD2
|
A:HIS574
|
4.6
|
28.3
|
1.0
|
CG2
|
A:VAL504
|
4.7
|
30.9
|
1.0
|
C17
|
A:E7M801
|
4.7
|
27.3
|
1.0
|
C25
|
A:E7M801
|
4.7
|
41.6
|
1.0
|
C23
|
A:E7M801
|
5.0
|
27.9
|
1.0
|
|
Fluorine binding site 4 out
of 12 in 6p7g
Go back to
Fluorine Binding Sites List in 6p7g
Fluorine binding site 4 out
of 12 in the The Co-Crystal Structure of Braf(V600E) with PHI1
Mono view
Stereo pair view
|
A full contact list of Fluorine with other atoms in the F binding
site number 4 of The Co-Crystal Structure of Braf(V600E) with PHI1 within 5.0Å range:
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
B:F801
b:37.5
occ:1.00
|
F1
|
B:E7M801
|
0.0
|
37.5
|
1.0
|
C20
|
B:E7M801
|
1.3
|
38.9
|
1.0
|
F3
|
B:E7M801
|
2.1
|
41.1
|
1.0
|
F2
|
B:E7M801
|
2.1
|
38.9
|
1.0
|
C19
|
B:E7M801
|
2.3
|
39.3
|
1.0
|
C24
|
B:E7M801
|
3.0
|
41.3
|
1.0
|
C21
|
B:E7M801
|
3.0
|
39.8
|
1.0
|
CD2
|
B:HIS574
|
3.3
|
32.9
|
1.0
|
C18
|
B:E7M801
|
3.4
|
39.1
|
1.0
|
NE2
|
B:HIS574
|
3.4
|
31.6
|
1.0
|
CA
|
B:GLY593
|
3.7
|
39.8
|
1.0
|
C
|
B:GLY593
|
3.9
|
42.1
|
1.0
|
CG2
|
B:ILE592
|
4.0
|
35.2
|
1.0
|
O
|
B:GLY593
|
4.1
|
42.5
|
1.0
|
CD1
|
B:LEU567
|
4.1
|
35.2
|
1.0
|
N
|
B:GLY593
|
4.2
|
37.5
|
1.0
|
CG
|
B:HIS574
|
4.3
|
31.6
|
1.0
|
C22
|
B:E7M801
|
4.3
|
38.6
|
1.0
|
CE1
|
B:HIS574
|
4.3
|
30.3
|
1.0
|
C
|
B:ILE592
|
4.4
|
34.4
|
1.0
|
O
|
B:ILE592
|
4.4
|
33.0
|
1.0
|
N5
|
B:E7M801
|
4.4
|
43.6
|
1.0
|
N
|
B:ASP594
|
4.5
|
46.3
|
1.0
|
C17
|
B:E7M801
|
4.6
|
36.6
|
1.0
|
ND1
|
B:HIS574
|
4.8
|
30.5
|
1.0
|
CB
|
B:ILE592
|
5.0
|
35.3
|
1.0
|
C23
|
B:E7M801
|
5.0
|
37.6
|
1.0
|
|
Fluorine binding site 5 out
of 12 in 6p7g
Go back to
Fluorine Binding Sites List in 6p7g
Fluorine binding site 5 out
of 12 in the The Co-Crystal Structure of Braf(V600E) with PHI1
Mono view
Stereo pair view
|
A full contact list of Fluorine with other atoms in the F binding
site number 5 of The Co-Crystal Structure of Braf(V600E) with PHI1 within 5.0Å range:
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
B:F801
b:38.9
occ:1.00
|
F2
|
B:E7M801
|
0.0
|
38.9
|
1.0
|
C20
|
B:E7M801
|
1.3
|
38.9
|
1.0
|
F3
|
B:E7M801
|
2.1
|
41.1
|
1.0
|
F1
|
B:E7M801
|
2.1
|
37.5
|
1.0
|
C19
|
B:E7M801
|
2.4
|
39.3
|
1.0
|
C18
|
B:E7M801
|
2.7
|
39.1
|
1.0
|
C21
|
B:E7M801
|
3.7
|
39.8
|
1.0
|
CD2
|
B:LEU505
|
3.7
|
28.3
|
1.0
|
CG2
|
B:ILE513
|
3.7
|
24.9
|
1.0
|
CA
|
B:GLY593
|
4.0
|
39.8
|
1.0
|
O
|
B:ILE592
|
4.0
|
33.0
|
1.0
|
C17
|
B:E7M801
|
4.1
|
36.6
|
1.0
|
C24
|
B:E7M801
|
4.3
|
41.3
|
1.0
|
O1
|
B:E7M801
|
4.5
|
28.9
|
1.0
|
C
|
B:ILE592
|
4.6
|
34.4
|
1.0
|
N
|
B:GLY593
|
4.7
|
37.5
|
1.0
|
C
|
B:GLY593
|
4.7
|
42.1
|
1.0
|
C22
|
B:E7M801
|
4.8
|
38.6
|
1.0
|
N4
|
B:E7M801
|
4.9
|
32.8
|
1.0
|
CG
|
B:LEU505
|
4.9
|
27.7
|
1.0
|
C23
|
B:E7M801
|
4.9
|
37.6
|
1.0
|
|
Fluorine binding site 6 out
of 12 in 6p7g
Go back to
Fluorine Binding Sites List in 6p7g
Fluorine binding site 6 out
of 12 in the The Co-Crystal Structure of Braf(V600E) with PHI1
Mono view
Stereo pair view
|
A full contact list of Fluorine with other atoms in the F binding
site number 6 of The Co-Crystal Structure of Braf(V600E) with PHI1 within 5.0Å range:
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
B:F801
b:41.1
occ:1.00
|
F3
|
B:E7M801
|
0.0
|
41.1
|
1.0
|
C20
|
B:E7M801
|
1.3
|
38.9
|
1.0
|
F2
|
B:E7M801
|
2.1
|
38.9
|
1.0
|
F1
|
B:E7M801
|
2.1
|
37.5
|
1.0
|
C19
|
B:E7M801
|
2.4
|
39.3
|
1.0
|
C24
|
B:E7M801
|
2.9
|
41.3
|
1.0
|
C21
|
B:E7M801
|
3.0
|
39.8
|
1.0
|
C18
|
B:E7M801
|
3.5
|
39.1
|
1.0
|
CD2
|
B:LEU567
|
4.1
|
33.7
|
1.0
|
CD1
|
B:LEU567
|
4.1
|
35.2
|
1.0
|
N5
|
B:E7M801
|
4.2
|
43.6
|
1.0
|
C22
|
B:E7M801
|
4.3
|
38.6
|
1.0
|
CG2
|
B:ILE572
|
4.4
|
37.0
|
1.0
|
C25
|
B:E7M801
|
4.5
|
44.8
|
1.0
|
C26
|
B:E7M801
|
4.6
|
47.1
|
1.0
|
C17
|
B:E7M801
|
4.6
|
36.6
|
1.0
|
CG2
|
B:VAL504
|
4.7
|
31.2
|
1.0
|
CD2
|
B:LEU505
|
4.7
|
28.3
|
1.0
|
CG
|
B:LEU567
|
4.8
|
34.9
|
1.0
|
CD2
|
B:HIS574
|
4.9
|
32.9
|
1.0
|
CG2
|
B:ILE513
|
4.9
|
24.9
|
1.0
|
CG1
|
B:VAL504
|
4.9
|
31.7
|
1.0
|
C23
|
B:E7M801
|
5.0
|
37.6
|
1.0
|
|
Fluorine binding site 7 out
of 12 in 6p7g
Go back to
Fluorine Binding Sites List in 6p7g
Fluorine binding site 7 out
of 12 in the The Co-Crystal Structure of Braf(V600E) with PHI1
Mono view
Stereo pair view
|
A full contact list of Fluorine with other atoms in the F binding
site number 7 of The Co-Crystal Structure of Braf(V600E) with PHI1 within 5.0Å range:
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
C:F1001
b:31.1
occ:1.00
|
F1
|
C:E7M1001
|
0.0
|
31.1
|
1.0
|
C20
|
C:E7M1001
|
1.3
|
31.9
|
1.0
|
F3
|
C:E7M1001
|
2.1
|
31.1
|
1.0
|
F2
|
C:E7M1001
|
2.1
|
31.9
|
1.0
|
C19
|
C:E7M1001
|
2.3
|
31.7
|
1.0
|
C21
|
C:E7M1001
|
3.1
|
33.6
|
1.0
|
CD2
|
C:HIS574
|
3.1
|
32.8
|
1.0
|
NE2
|
C:HIS574
|
3.1
|
33.4
|
1.0
|
C24
|
C:E7M1001
|
3.1
|
37.6
|
1.0
|
C18
|
C:E7M1001
|
3.3
|
30.9
|
1.0
|
CA
|
C:GLY593
|
3.9
|
28.5
|
1.0
|
C
|
C:GLY593
|
3.9
|
28.9
|
1.0
|
O
|
C:GLY593
|
4.0
|
27.0
|
1.0
|
CG2
|
C:ILE592
|
4.0
|
27.6
|
1.0
|
CG
|
C:HIS574
|
4.0
|
32.2
|
1.0
|
CE1
|
C:HIS574
|
4.1
|
33.3
|
1.0
|
CD1
|
C:LEU567
|
4.1
|
34.4
|
1.0
|
N
|
C:GLY593
|
4.3
|
28.3
|
1.0
|
C22
|
C:E7M1001
|
4.3
|
32.2
|
1.0
|
N5
|
C:E7M1001
|
4.4
|
41.8
|
1.0
|
N
|
C:ASP594
|
4.5
|
33.1
|
1.0
|
ND1
|
C:HIS574
|
4.5
|
31.9
|
1.0
|
C17
|
C:E7M1001
|
4.6
|
30.8
|
1.0
|
C
|
C:ILE592
|
4.6
|
28.6
|
1.0
|
O
|
C:ILE592
|
4.7
|
28.5
|
1.0
|
C23
|
C:E7M1001
|
4.9
|
31.3
|
1.0
|
CB
|
C:HIS574
|
5.0
|
34.3
|
1.0
|
|
Fluorine binding site 8 out
of 12 in 6p7g
Go back to
Fluorine Binding Sites List in 6p7g
Fluorine binding site 8 out
of 12 in the The Co-Crystal Structure of Braf(V600E) with PHI1
Mono view
Stereo pair view
|
A full contact list of Fluorine with other atoms in the F binding
site number 8 of The Co-Crystal Structure of Braf(V600E) with PHI1 within 5.0Å range:
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
C:F1001
b:31.9
occ:1.00
|
F2
|
C:E7M1001
|
0.0
|
31.9
|
1.0
|
C20
|
C:E7M1001
|
1.3
|
31.9
|
1.0
|
F1
|
C:E7M1001
|
2.1
|
31.1
|
1.0
|
F3
|
C:E7M1001
|
2.1
|
31.1
|
1.0
|
C19
|
C:E7M1001
|
2.4
|
31.7
|
1.0
|
C18
|
C:E7M1001
|
2.7
|
30.9
|
1.0
|
C21
|
C:E7M1001
|
3.7
|
33.6
|
1.0
|
CG2
|
C:ILE513
|
3.8
|
25.9
|
1.0
|
CA
|
C:GLY593
|
3.8
|
28.5
|
1.0
|
O
|
C:ILE592
|
3.9
|
28.5
|
1.0
|
CD2
|
C:LEU505
|
4.0
|
38.4
|
1.0
|
C17
|
C:E7M1001
|
4.1
|
30.8
|
1.0
|
C24
|
C:E7M1001
|
4.3
|
37.6
|
1.0
|
O1
|
C:E7M1001
|
4.4
|
31.1
|
1.0
|
C
|
C:ILE592
|
4.4
|
28.6
|
1.0
|
N
|
C:GLY593
|
4.4
|
28.3
|
1.0
|
C
|
C:GLY593
|
4.5
|
28.9
|
1.0
|
C22
|
C:E7M1001
|
4.8
|
32.2
|
1.0
|
N
|
C:ASP594
|
4.9
|
33.1
|
1.0
|
CD1
|
C:LEU567
|
4.9
|
34.4
|
1.0
|
CD2
|
C:LEU567
|
5.0
|
32.9
|
1.0
|
C23
|
C:E7M1001
|
5.0
|
31.3
|
1.0
|
N4
|
C:E7M1001
|
5.0
|
30.1
|
1.0
|
CG2
|
C:ILE592
|
5.0
|
27.6
|
1.0
|
|
Fluorine binding site 9 out
of 12 in 6p7g
Go back to
Fluorine Binding Sites List in 6p7g
Fluorine binding site 9 out
of 12 in the The Co-Crystal Structure of Braf(V600E) with PHI1
Mono view
Stereo pair view
|
A full contact list of Fluorine with other atoms in the F binding
site number 9 of The Co-Crystal Structure of Braf(V600E) with PHI1 within 5.0Å range:
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
C:F1001
b:31.1
occ:1.00
|
F3
|
C:E7M1001
|
0.0
|
31.1
|
1.0
|
C20
|
C:E7M1001
|
1.3
|
31.9
|
1.0
|
F1
|
C:E7M1001
|
2.1
|
31.1
|
1.0
|
F2
|
C:E7M1001
|
2.1
|
31.9
|
1.0
|
C19
|
C:E7M1001
|
2.4
|
31.7
|
1.0
|
C24
|
C:E7M1001
|
2.9
|
37.6
|
1.0
|
C21
|
C:E7M1001
|
3.0
|
33.6
|
1.0
|
C18
|
C:E7M1001
|
3.5
|
30.9
|
1.0
|
CD2
|
C:LEU567
|
4.0
|
32.9
|
1.0
|
CD1
|
C:LEU567
|
4.1
|
34.4
|
1.0
|
N5
|
C:E7M1001
|
4.3
|
41.8
|
1.0
|
C22
|
C:E7M1001
|
4.3
|
32.2
|
1.0
|
CG2
|
C:ILE572
|
4.3
|
41.5
|
1.0
|
CG2
|
C:VAL504
|
4.6
|
36.2
|
1.0
|
CD2
|
C:HIS574
|
4.7
|
32.8
|
1.0
|
CG
|
C:LEU567
|
4.7
|
33.0
|
1.0
|
C17
|
C:E7M1001
|
4.7
|
30.8
|
1.0
|
C25
|
C:E7M1001
|
4.9
|
45.9
|
1.0
|
CG1
|
C:VAL504
|
4.9
|
36.7
|
1.0
|
CD2
|
C:LEU505
|
4.9
|
38.4
|
1.0
|
|
Fluorine binding site 10 out
of 12 in 6p7g
Go back to
Fluorine Binding Sites List in 6p7g
Fluorine binding site 10 out
of 12 in the The Co-Crystal Structure of Braf(V600E) with PHI1
Mono view
Stereo pair view
|
A full contact list of Fluorine with other atoms in the F binding
site number 10 of The Co-Crystal Structure of Braf(V600E) with PHI1 within 5.0Å range:
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
D:F801
b:49.2
occ:1.00
|
F1
|
D:E7M801
|
0.0
|
49.2
|
1.0
|
C20
|
D:E7M801
|
1.3
|
48.8
|
1.0
|
F3
|
D:E7M801
|
2.1
|
48.9
|
1.0
|
F2
|
D:E7M801
|
2.1
|
44.7
|
1.0
|
C19
|
D:E7M801
|
2.4
|
51.2
|
1.0
|
C21
|
D:E7M801
|
3.0
|
55.2
|
1.0
|
C24
|
D:E7M801
|
3.1
|
58.7
|
1.0
|
C18
|
D:E7M801
|
3.4
|
51.7
|
1.0
|
CD2
|
D:LEU567
|
4.1
|
37.9
|
1.0
|
CD1
|
D:LEU567
|
4.3
|
37.3
|
1.0
|
C22
|
D:E7M801
|
4.3
|
55.0
|
1.0
|
CG2
|
D:ILE572
|
4.4
|
52.8
|
1.0
|
N5
|
D:E7M801
|
4.5
|
65.5
|
1.0
|
CG2
|
D:VAL504
|
4.5
|
54.4
|
1.0
|
CD2
|
D:LEU505
|
4.6
|
59.7
|
1.0
|
C17
|
D:E7M801
|
4.6
|
52.8
|
1.0
|
CG1
|
D:VAL504
|
4.7
|
57.1
|
1.0
|
CG
|
D:LEU567
|
4.9
|
37.7
|
1.0
|
CG2
|
D:ILE513
|
4.9
|
32.8
|
1.0
|
CD2
|
D:HIS574
|
5.0
|
44.9
|
1.0
|
C23
|
D:E7M801
|
5.0
|
53.5
|
1.0
|
|
Reference:
X.M.Cotto-Rios,
B.Agianian,
N.Gitego,
E.Zacharioudakis,
O.Giricz,
Y.Wu,
Y.Zou,
A.Verma,
P.I.Poulikakos,
E.Gavathiotis.
Inhibitors of Braf Dimers Using An Allosteric Site. Nat Commun V. 11 4370 2020.
ISSN: ESSN 2041-1723
PubMed: 32873792
DOI: 10.1038/S41467-020-18123-2
Page generated: Fri Aug 2 00:08:34 2024
|