Fluorine in PDB 6qul: Structure of A Bacterial 50S Ribosomal Subunit in Complex with the Novel Quinoxolidinone Antibiotic Cadazolid

The structure of Structure of A Bacterial 50S Ribosomal Subunit in Complex with the Novel Quinoxolidinone Antibiotic Cadazolid also contains other interesting chemical elements:

Magnesium	(Mg)	382 atoms
Zinc	(Zn)	1 atom

The binding sites of Fluorine atom in the Structure of A Bacterial 50S Ribosomal Subunit in Complex with the Novel Quinoxolidinone Antibiotic Cadazolid (pdb code 6qul). This binding sites where shown within 5.0 Angstroms radius around Fluorine atom.
In total 2 binding sites of Fluorine where determined in the Structure of A Bacterial 50S Ribosomal Subunit in Complex with the Novel Quinoxolidinone Antibiotic Cadazolid, PDB code: 6qul:
Jump to Fluorine binding site number: 1; 2;

Fluorine binding site 1 out of 2 in the Structure of A Bacterial 50S Ribosomal Subunit in Complex with the Novel Quinoxolidinone Antibiotic Cadazolid


Mono view


Stereo pair view

A full contact list of Fluorine with other atoms in the F binding site number 1 of Structure of A Bacterial 50S Ribosomal Subunit in Complex with the Novel Quinoxolidinone Antibiotic Cadazolid within 5.0Å range: probe atom residue distance (Å) B Occ A:F3370 b:33.1 occ:1.00 FAA A:JJH3370 0.0 33.1 1.0 CBC A:JJH3370 1.3 33.1 1.0 CBE A:JJH3370 2.4 33.1 1.0 CAW A:JJH3370 2.4 33.1 1.0 HAZ A:JJH3370 2.6 33.1 1.0 HBE A:JJH3370 2.6 33.1 1.0 NAL A:JJH3370 2.8 33.1 1.0 CAV A:JJH3370 3.1 33.1 1.0 C5' 1:A76 3.1 17.3 1.0 HAV A:JJH3370 3.3 33.1 1.0 C3' 1:A76 3.5 17.3 1.0 CBA A:JJH3370 3.6 33.1 1.0 CAZ A:JJH3370 3.6 33.1 1.0 N6 A:A2602 3.7 14.5 0.5 CAS A:JJH3370 3.7 33.1 1.0 C4' 1:A76 3.8 17.3 1.0 CAU A:JJH3370 3.9 33.1 1.0 C2' 1:A76 4.0 17.3 1.0 HAY A:JJH3370 4.0 33.1 1.0 HAS A:JJH3370 4.0 33.1 1.0 HAW A:JJH3370 4.0 33.1 1.0 CAT A:JJH3370 4.1 33.1 1.0 O5' 1:A76 4.2 17.3 1.0 C6 A:A2602 4.3 14.5 0.5 N7 A:A2602 4.3 14.5 0.5 O2' A:U2584 4.4 20.8 1.0 CAR A:JJH3370 4.4 33.1 1.0 HAU A:JJH3370 4.5 33.1 1.0 HA3 A:JJH3370 4.5 33.1 1.0 C5 A:A2602 4.5 14.5 0.5 CAQ A:JJH3370 4.7 33.1 1.0 CBD A:JJH3370 4.7 33.1 1.0 HAX A:JJH3370 4.8 33.1 1.0 O3' 1:A76 4.8 17.3 1.0 O4' 1:A76 4.8 17.3 1.0 O2' 1:A76 4.9 17.3 1.0 OAE A:JJH3370 4.9 33.1 1.0 C 1:FME101 4.9 17.3 1.0

Fluorine binding site 2 out of 2 in the Structure of A Bacterial 50S Ribosomal Subunit in Complex with the Novel Quinoxolidinone Antibiotic Cadazolid


Mono view


Stereo pair view

A full contact list of Fluorine with other atoms in the F binding site number 2 of Structure of A Bacterial 50S Ribosomal Subunit in Complex with the Novel Quinoxolidinone Antibiotic Cadazolid within 5.0Å range: probe atom residue distance (Å) B Occ A:F3370 b:33.1 occ:1.00 FAB A:JJH3370 0.0 33.1 1.0 CBH A:JJH3370 1.3 33.1 1.0 CBG A:JJH3370 2.3 33.1 1.0 CBM A:JJH3370 2.3 33.1 1.0 HBN A:JJH3370 2.6 33.1 1.0 OAD A:JJH3370 2.6 33.1 1.0 O4' A:U2506 2.8 19.8 1.0 HA1 A:JJH3370 3.0 33.1 1.0 C4' A:U2506 3.0 19.8 1.0 C5' A:U2506 3.3 19.8 1.0 CAY A:JJH3370 3.3 33.1 1.0 OAC A:JJH3370 3.5 33.1 1.0 HAC A:JJH3370 3.5 33.1 1.0 O4' A:C2452 3.5 13.0 1.0 CBI A:JJH3370 3.6 33.1 1.0 CBJ A:JJH3370 3.6 33.1 1.0 C1' A:C2452 3.6 13.0 1.0 C1' A:U2506 3.9 19.8 1.0 HAT A:JJH3370 3.9 33.1 1.0 CAQ A:JJH3370 3.9 33.1 1.0 O2 A:C2452 4.0 13.0 1.0 CBN A:JJH3370 4.1 33.1 1.0 N1 A:C2452 4.2 13.0 1.0 HA2 A:JJH3370 4.2 33.1 1.0 C2 A:C2452 4.3 13.0 1.0 O2' A:G2505 4.4 16.6 1.0 C3' A:U2506 4.4 19.8 1.0 HBI A:JJH3370 4.5 33.1 1.0 O5' A:U2506 4.5 19.8 1.0 CAR A:JJH3370 4.6 33.1 1.0 O2' A:U2506 4.7 19.8 1.0 C4' A:C2452 4.7 13.0 1.0 C2' A:U2506 4.7 19.8 1.0 NAM A:JJH3370 4.7 33.1 1.0 OAJ A:JJH3370 4.9 33.1 1.0 CE 1:FME101 4.9 17.3 1.0 O2' A:C2452 4.9 13.0 1.0 C2' A:C2452 4.9 13.0 1.0

A.Scaiola, M.Leibundgut, D.Boehringer, P.Caspers, D.Bur, H.H.Locher, G.Rueedi, D.Ritz. Structural Basis of Translation Inhibition By Cadazolid, A Novel Quinoxolidinone Antibiotic. Sci Rep V. 9 5634 2019.
ISSN: ESSN 2045-2322
PubMed: 30948752
DOI: 10.1038/S41598-019-42155-4