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Fluorine in PDB 6rz7: Crystal Structure of the Human Cysteinyl Leukotriene Receptor 2 in Complex with Ono-2570366 (F222 Space Group)Protein crystallography data
The structure of Crystal Structure of the Human Cysteinyl Leukotriene Receptor 2 in Complex with Ono-2570366 (F222 Space Group), PDB code: 6rz7
was solved by
A.Gusach,
A.Luginina,
E.Marin,
R.L.Brouillette,
E.Besserer-Offroy,
J.M.Longpre,
A.Ishchenko,
P.Popov,
T.Fujimoto,
T.Maruyama,
B.Stauch,
M.Ergasheva,
D.Romanovskaya,
A.Stepko,
K.Kovalev,
M.Shevtsov,
V.Gordeliy,
G.W.Han,
P.Sarret,
V.Katritch,
V.Borshchevskiy,
A.Mishin,
V.Cherezov,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Other elements in 6rz7:
The structure of Crystal Structure of the Human Cysteinyl Leukotriene Receptor 2 in Complex with Ono-2570366 (F222 Space Group) also contains other interesting chemical elements:
Fluorine Binding Sites:
The binding sites of Fluorine atom in the Crystal Structure of the Human Cysteinyl Leukotriene Receptor 2 in Complex with Ono-2570366 (F222 Space Group)
(pdb code 6rz7). This binding sites where shown within
5.0 Angstroms radius around Fluorine atom.
In total only one binding site of Fluorine was determined in the Crystal Structure of the Human Cysteinyl Leukotriene Receptor 2 in Complex with Ono-2570366 (F222 Space Group), PDB code: 6rz7: Fluorine binding site 1 out of 1 in 6rz7Go back to Fluorine Binding Sites List in 6rz7
Fluorine binding site 1 out
of 1 in the Crystal Structure of the Human Cysteinyl Leukotriene Receptor 2 in Complex with Ono-2570366 (F222 Space Group)
Mono view Stereo pair view
Reference:
A.Gusach,
A.Luginina,
E.Marin,
R.L.Brouillette,
E.Besserer-Offroy,
J.M.Longpre,
A.Ishchenko,
P.Popov,
N.Patel,
T.Fujimoto,
T.Maruyama,
B.Stauch,
M.Ergasheva,
D.Romanovskaia,
A.Stepko,
K.Kovalev,
M.Shevtsov,
V.Gordeliy,
G.W.Han,
V.Katritch,
V.Borshchevskiy,
P.Sarret,
A.Mishin,
V.Cherezov.
Structural Basis of Ligand Selectivity and Disease Mutations in Cysteinyl Leukotriene Receptors. Nat Commun V. 10 5573 2019.
Page generated: Sun Dec 13 13:10:46 2020
ISSN: ESSN 2041-1723 PubMed: 31811124 DOI: 10.1038/S41467-019-13348-2 |
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