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Fluorine in PDB 6sdc: Crystal Structure of D1228V Cmet Bound By ForetinibEnzymatic activity of Crystal Structure of D1228V Cmet Bound By Foretinib
All present enzymatic activity of Crystal Structure of D1228V Cmet Bound By Foretinib:
2.7.10.1; Protein crystallography data
The structure of Crystal Structure of D1228V Cmet Bound By Foretinib, PDB code: 6sdc
was solved by
G.W.Collie,
C.Phillips,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Fluorine Binding Sites:
The binding sites of Fluorine atom in the Crystal Structure of D1228V Cmet Bound By Foretinib
(pdb code 6sdc). This binding sites where shown within
5.0 Angstroms radius around Fluorine atom.
In total 2 binding sites of Fluorine where determined in the Crystal Structure of D1228V Cmet Bound By Foretinib, PDB code: 6sdc: Jump to Fluorine binding site number: 1; 2; Fluorine binding site 1 out of 2 in 6sdcGo back to Fluorine Binding Sites List in 6sdc
Fluorine binding site 1 out
of 2 in the Crystal Structure of D1228V Cmet Bound By Foretinib
Mono view Stereo pair view
Fluorine binding site 2 out of 2 in 6sdcGo back to Fluorine Binding Sites List in 6sdc
Fluorine binding site 2 out
of 2 in the Crystal Structure of D1228V Cmet Bound By Foretinib
Mono view Stereo pair view
Reference:
G.W.Collie,
C.M.Koh,
D.J.O'neill,
C.J.Stubbs,
P.Khurana,
A.Eddershaw,
A.Snijder,
F.Mauritzson,
L.Barlind,
I.L.Dale,
J.Shaw,
C.Phillips,
E.J.Hennessy,
T.Cheung,
A.J.Narvaez.
Structural and Molecular Insight Into Resistance Mechanisms of First Generation Cmet Inhibitors. Acs Med.Chem.Lett. V. 10 1322 2019.
Page generated: Sun Dec 13 13:12:01 2020
ISSN: ISSN 1948-5875 PubMed: 31531204 DOI: 10.1021/ACSMEDCHEMLETT.9B00276 |
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