Fluorine in PDB 6t3w: Coxsackie B3 2C Protein in Complex with S-Fluoxetine
Enzymatic activity of Coxsackie B3 2C Protein in Complex with S-Fluoxetine
All present enzymatic activity of Coxsackie B3 2C Protein in Complex with S-Fluoxetine:
2.7.7.48; 3.4.22.28; 3.4.22.29; 3.6.1.15;
2.7.7.48; 3.4.22.28; 3.4.22.29; 3.6.1.15;
Protein crystallography data
The structure of Coxsackie B3 2C Protein in Complex with S-Fluoxetine, PDB code: 6t3w
was solved by
P.El Kazzi,
N.Papageorgiou,
F.P.Ferron,
L.Bauer,
F.Van Kuppeveld,
B.Coutard,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
| Resolution Low / High (Å) | 39.69 / 1.82 |
| Space group | P 21 21 21 |
| Cell size a, b, c (Å), α, β, γ (°) | 47.992, 53.008, 79.369, 90.00, 90.00, 90.00 |
| R / Rfree (%) | 19.4 / 22.2 |
Other elements in 6t3w:
The structure of Coxsackie B3 2C Protein in Complex with S-Fluoxetine also contains other interesting chemical elements:
| Zinc | (Zn) | 1 atom |
| Sodium | (Na) | 2 atoms |
Fluorine Binding Sites:
The binding sites of Fluorine atom in the Coxsackie B3 2C Protein in Complex with S-Fluoxetine
(pdb code 6t3w). This binding sites where shown within
5.0 Angstroms radius around Fluorine atom.
In total 3 binding sites of Fluorine where determined in the Coxsackie B3 2C Protein in Complex with S-Fluoxetine, PDB code: 6t3w:
Jump to Fluorine binding site number: 1; 2; 3;
In total 3 binding sites of Fluorine where determined in the Coxsackie B3 2C Protein in Complex with S-Fluoxetine, PDB code: 6t3w:
Jump to Fluorine binding site number: 1; 2; 3;
Fluorine binding site 1 out of 3 in 6t3w
Go back to
Fluorine Binding Sites List in 6t3w
Fluorine binding site 1 out
of 3 in the Coxsackie B3 2C Protein in Complex with S-Fluoxetine
Mono view
Stereo pair view
Mono view
Stereo pair view
A full contact list of Fluorine with other atoms in the F binding
site number 1 of Coxsackie B3 2C Protein in Complex with S-Fluoxetine within 5.0Å range:
|
Fluorine binding site 2 out of 3 in 6t3w
Go back to
Fluorine Binding Sites List in 6t3w
Fluorine binding site 2 out
of 3 in the Coxsackie B3 2C Protein in Complex with S-Fluoxetine
Mono view
Stereo pair view
Mono view
Stereo pair view
A full contact list of Fluorine with other atoms in the F binding
site number 2 of Coxsackie B3 2C Protein in Complex with S-Fluoxetine within 5.0Å range:
|
Fluorine binding site 3 out of 3 in 6t3w
Go back to
Fluorine Binding Sites List in 6t3w
Fluorine binding site 3 out
of 3 in the Coxsackie B3 2C Protein in Complex with S-Fluoxetine
Mono view
Stereo pair view
Mono view
Stereo pair view
A full contact list of Fluorine with other atoms in the F binding
site number 3 of Coxsackie B3 2C Protein in Complex with S-Fluoxetine within 5.0Å range:
|
Reference:
P.El Kazzi,
L.Bauer,
N.Papageorgiou,
F.P.Ferron,
E.Decroly,
B.Canard,
A.Brancale,
F.Van Kupperveld,
B.Coutard.
The Crystal Structure of Enterovirus 2C Catalytic Domain in Complex Withs-Fluoxetine Reveals Its Antiviral Mode of Action. To Be Published.
Page generated: Sun Dec 13 13:12:53 2020
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