Atomistry » Fluorine » PDB 6slz-6tan » 6ta3
Atomistry »
  Fluorine »
    PDB 6slz-6tan »
      6ta3 »

Fluorine in PDB 6ta3: Human Kinesin-5 Motor Domain in the Gsk-1 State Bound to Microtubules (Conformation 1)

Other elements in 6ta3:

The structure of Human Kinesin-5 Motor Domain in the Gsk-1 State Bound to Microtubules (Conformation 1) also contains other interesting chemical elements:

Magnesium (Mg) 2 atoms

Fluorine Binding Sites:

The binding sites of Fluorine atom in the Human Kinesin-5 Motor Domain in the Gsk-1 State Bound to Microtubules (Conformation 1) (pdb code 6ta3). This binding sites where shown within 5.0 Angstroms radius around Fluorine atom.
In total 3 binding sites of Fluorine where determined in the Human Kinesin-5 Motor Domain in the Gsk-1 State Bound to Microtubules (Conformation 1), PDB code: 6ta3:
Jump to Fluorine binding site number: 1; 2; 3;

Fluorine binding site 1 out of 3 in 6ta3

Go back to Fluorine Binding Sites List in 6ta3
Fluorine binding site 1 out of 3 in the Human Kinesin-5 Motor Domain in the Gsk-1 State Bound to Microtubules (Conformation 1)


Mono view


Stereo pair view

A full contact list of Fluorine with other atoms in the F binding site number 1 of Human Kinesin-5 Motor Domain in the Gsk-1 State Bound to Microtubules (Conformation 1) within 5.0Å range:
probe atom residue distance (Å) B Occ
K:F501

b:0.0
occ:1.00
F1 K:MZK501 0.0 0.0 1.0
C16 K:MZK501 1.4 0.0 1.0
F2 K:MZK501 2.1 0.0 1.0
F3 K:MZK501 2.2 0.0 1.0
C13 K:MZK501 2.4 0.0 1.0
OE2 K:GLU345 2.7 0.8 1.0
NE2 K:GLN106 2.9 0.8 1.0
C15 K:MZK501 3.1 0.0 1.0
CG K:GLU345 3.3 0.8 1.0
C14 K:MZK501 3.4 0.0 1.0
CD K:GLU345 3.5 0.8 1.0
CB K:GLU345 3.7 0.8 1.0
CD K:GLN106 3.9 0.8 1.0
CA K:GLU345 3.9 0.8 1.0
CG2 K:THR349 3.9 0.7 1.0
OE1 K:GLN106 4.1 0.8 1.0
O K:GLU345 4.1 0.8 1.0
C12 K:MZK501 4.4 0.0 1.0
CA K:GLY105 4.4 0.8 1.0
C K:GLU345 4.5 0.8 1.0
C11 K:MZK501 4.6 0.0 1.0
C K:GLY105 4.6 0.8 1.0
OE1 K:GLU345 4.7 0.8 1.0
CB K:SER348 4.7 0.7 1.0
CE2 K:TYR104 4.8 0.8 1.0
O K:GLY105 4.8 0.8 1.0
CD2 K:TYR104 4.9 0.8 1.0

Fluorine binding site 2 out of 3 in 6ta3

Go back to Fluorine Binding Sites List in 6ta3
Fluorine binding site 2 out of 3 in the Human Kinesin-5 Motor Domain in the Gsk-1 State Bound to Microtubules (Conformation 1)


Mono view


Stereo pair view

A full contact list of Fluorine with other atoms in the F binding site number 2 of Human Kinesin-5 Motor Domain in the Gsk-1 State Bound to Microtubules (Conformation 1) within 5.0Å range:
probe atom residue distance (Å) B Occ
K:F501

b:0.0
occ:1.00
F2 K:MZK501 0.0 0.0 1.0
C16 K:MZK501 1.4 0.0 1.0
F1 K:MZK501 2.1 0.0 1.0
F3 K:MZK501 2.1 0.0 1.0
C13 K:MZK501 2.4 0.0 1.0
C15 K:MZK501 2.8 0.0 1.0
CE2 K:TYR104 2.9 0.8 1.0
CD2 K:TYR104 3.0 0.8 1.0
C14 K:MZK501 3.7 0.0 1.0
CA K:GLY105 3.7 0.8 1.0
N K:GLY105 3.7 0.8 1.0
O K:GLY105 3.8 0.8 1.0
CZ K:TYR104 3.9 0.8 1.0
NE2 K:GLN106 3.9 0.8 1.0
C K:GLY105 4.0 0.8 1.0
CG K:TYR104 4.1 0.8 1.0
C12 K:MZK501 4.2 0.0 1.0
OE2 K:GLU345 4.3 0.8 1.0
CD1 K:LEU266 4.4 0.7 1.0
CD2 K:LEU292 4.5 0.7 1.0
OH K:TYR104 4.5 0.8 1.0
OE1 K:GLN106 4.7 0.8 1.0
CE1 K:TYR104 4.7 0.8 1.0
CD1 K:TYR104 4.8 0.8 1.0
C11 K:MZK501 4.8 0.0 1.0
CD K:GLN106 4.8 0.8 1.0
CG2 K:THR349 4.9 0.7 1.0
C K:TYR104 4.9 0.8 1.0

Fluorine binding site 3 out of 3 in 6ta3

Go back to Fluorine Binding Sites List in 6ta3
Fluorine binding site 3 out of 3 in the Human Kinesin-5 Motor Domain in the Gsk-1 State Bound to Microtubules (Conformation 1)


Mono view


Stereo pair view

A full contact list of Fluorine with other atoms in the F binding site number 3 of Human Kinesin-5 Motor Domain in the Gsk-1 State Bound to Microtubules (Conformation 1) within 5.0Å range:
probe atom residue distance (Å) B Occ
K:F501

b:0.0
occ:1.00
F3 K:MZK501 0.0 0.0 1.0
C16 K:MZK501 1.3 0.0 1.0
F2 K:MZK501 2.1 0.0 1.0
F1 K:MZK501 2.2 0.0 1.0
C13 K:MZK501 2.4 0.0 1.0
OE2 K:GLU345 2.7 0.8 1.0
C14 K:MZK501 2.9 0.0 1.0
CD2 K:LEU292 3.5 0.7 1.0
C15 K:MZK501 3.7 0.0 1.0
CD K:GLU345 3.7 0.8 1.0
CG K:GLU345 4.1 0.8 1.0
CE2 K:TYR104 4.2 0.8 1.0
C11 K:MZK501 4.3 0.0 1.0
NE2 K:GLN106 4.4 0.8 1.0
OE1 K:GLN106 4.6 0.8 1.0
CD2 K:TYR104 4.8 0.8 1.0
OE1 K:GLU345 4.8 0.8 1.0
C12 K:MZK501 4.8 0.0 1.0
CG K:LEU292 4.9 0.7 1.0
CZ K:TYR104 5.0 0.8 1.0

Reference:

A.Pena, A.Sweeney, A.D.Cook, M.Topf, C.A.Moores. Structure of Microtubule-Trapped Human Kinesin-5 and Its Mechanism of Inhibition Revealed Using Cryoelectron Microscopy. Structure V. 28 450 2020.
ISSN: ISSN 0969-2126
PubMed: 32084356
DOI: 10.1016/J.STR.2020.01.013
Page generated: Fri Aug 2 01:57:01 2024

Last articles

Zn in 9MJ5
Zn in 9HNW
Zn in 9G0L
Zn in 9FNE
Zn in 9DZN
Zn in 9E0I
Zn in 9D32
Zn in 9DAK
Zn in 8ZXC
Zn in 8ZUF
© Copyright 2008-2020 by atomistry.com
Home   |    Site Map   |    Copyright   |    Contact us   |    Privacy