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Fluorine in PDB 6u36: PCSK9 in Complex with A Fab and Compound 14Protein crystallography data
The structure of PCSK9 in Complex with A Fab and Compound 14, PDB code: 6u36
was solved by
J.Lu,
S.Soisson,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Fluorine Binding Sites:
The binding sites of Fluorine atom in the PCSK9 in Complex with A Fab and Compound 14
(pdb code 6u36). This binding sites where shown within
5.0 Angstroms radius around Fluorine atom.
In total only one binding site of Fluorine was determined in the PCSK9 in Complex with A Fab and Compound 14, PDB code: 6u36: Fluorine binding site 1 out of 1 in 6u36Go back to Fluorine Binding Sites List in 6u36
Fluorine binding site 1 out
of 1 in the PCSK9 in Complex with A Fab and Compound 14
Mono view Stereo pair view
Reference:
W.L.Petrilli,
G.C.Adam,
R.S.Erdmann,
P.Abeywickrema,
V.Agnani,
X.Ai,
J.Baysarowich,
N.Byrne,
J.P.Caldwell,
W.Chang,
E.Dinunzio,
Z.Feng,
R.Ford,
S.Ha,
Y.Huang,
B.Hubbard,
J.M.Johnston,
M.Kavana,
J.M.Lisnock,
R.Liang,
J.Lu,
Z.Lu,
J.Meng,
P.Orth,
O.Palyha,
G.Parthasarathy,
S.P.Salowe,
S.Sharma,
J.Shipman,
S.M.Soisson,
A.M.Strack,
H.Youm,
K.Zhao,
D.L.Zink,
H.Zokian,
G.H.Addona,
K.Akinsanya,
J.R.Tata,
Y.Xiong,
J.E.Imbriglio.
From Screening to Targeted Degradation: Strategies For the Discovery and Optimization of Small Molecule Ligands For PCSK9. Cell Chem Biol 2019.
Page generated: Sun Dec 13 13:16:42 2020
ISSN: ESSN 2451-9456 PubMed: 31653597 DOI: 10.1016/J.CHEMBIOL.2019.10.002 |
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