Fluorine in PDB 6vkv: Co-Crystal Structure of Gs-6207 Bound to Hiv-1 Capsid Hexamer

The structure of Co-Crystal Structure of Gs-6207 Bound to Hiv-1 Capsid Hexamer, PDB code: 6vkv was solved by S.M.Bester, M.Kvaratskhelia, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	44.26 / 2.22
Space group	P 6
Cell size a, b, c (Å), α, β, γ (°)	160.050, 160.050, 57.526, 90.00, 90.00, 120.00
R / Rfree (%)	23.1 / 26.9

The structure of Co-Crystal Structure of Gs-6207 Bound to Hiv-1 Capsid Hexamer also contains other interesting chemical elements:

Iodine	(I)	5 atoms
Chlorine	(Cl)	20 atoms

Pages:

>>> Page 1 <<< Page 2, Binding sites: 11 - 20; Page 3, Binding sites: 21 - 30; Page 4, Binding sites: 31 - 40; Page 5, Binding sites: 41 - 50; Page 6, Binding sites: 51 - 60;

Binding sites:

The binding sites of Fluorine atom in the Co-Crystal Structure of Gs-6207 Bound to Hiv-1 Capsid Hexamer (pdb code 6vkv). This binding sites where shown within 5.0 Angstroms radius around Fluorine atom.
In total 60 binding sites of Fluorine where determined in the Co-Crystal Structure of Gs-6207 Bound to Hiv-1 Capsid Hexamer, PDB code: 6vkv:
Jump to Fluorine binding site number: 1; 2; 3; 4; 5; 6; 7; 8; 9; 10;

Fluorine binding site 1 out of 60 in the Co-Crystal Structure of Gs-6207 Bound to Hiv-1 Capsid Hexamer


Mono view


Stereo pair view

A full contact list of Fluorine with other atoms in the F binding site number 1 of Co-Crystal Structure of Gs-6207 Bound to Hiv-1 Capsid Hexamer within 5.0Å range: probe atom residue distance (Å) B Occ A:F301 b:26.8 occ:0.51 F26 A:QNG301 0.0 26.8 0.5 F26 A:QNG301 0.2 26.9 0.2 C24 A:QNG301 1.4 26.0 0.5 C24 A:QNG301 1.4 26.1 0.2 C25 A:QNG301 2.3 27.3 0.2 C25 A:QNG301 2.4 27.3 0.5 C23 A:QNG301 2.4 25.9 0.5 C23 A:QNG301 2.5 26.3 0.2 CG A:LYS70 3.2 40.9 1.0 CD1 A:ILE73 3.2 34.0 1.0 N A:LYS70 3.2 30.6 1.0 CB A:LEU69 3.4 35.4 1.0 C A:LEU69 3.5 33.7 1.0 CG A:LEU69 3.5 36.8 1.0 CA A:LYS70 3.6 32.6 1.0 C20 A:QNG301 3.6 28.4 0.2 C20 A:QNG301 3.7 28.6 0.5 C22 A:QNG301 3.7 27.8 0.5 O A:MET66 3.7 26.5 1.0 C22 A:QNG301 3.7 27.9 0.2 O A:LEU69 3.9 33.1 1.0 CB A:LYS70 3.9 36.9 1.0 CD2 A:LEU69 4.0 31.2 1.0 CA A:LEU69 4.1 33.2 1.0 C21 A:QNG301 4.2 28.4 0.5 C21 A:QNG301 4.2 28.6 0.2 CD A:LYS70 4.4 44.3 1.0 CG1 A:ILE73 4.4 28.7 1.0 CD1 A:LEU56 4.4 18.3 1.0 F42 A:QNG301 4.6 33.7 0.5 F42 A:QNG301 4.6 33.6 0.2 F27 A:QNG301 4.8 30.9 0.5 C A:MET66 4.8 29.0 1.0 CD1 A:LEU69 4.8 40.0 1.0 C19 A:QNG301 4.9 29.3 0.2 F27 A:QNG301 4.9 30.1 0.2 C19 A:QNG301 4.9 29.0 0.5 C A:LYS70 5.0 33.4 1.0 N A:LEU69 5.0 28.3 1.0

Fluorine binding site 2 out of 60 in the Co-Crystal Structure of Gs-6207 Bound to Hiv-1 Capsid Hexamer


Mono view


Stereo pair view

A full contact list of Fluorine with other atoms in the F binding site number 2 of Co-Crystal Structure of Gs-6207 Bound to Hiv-1 Capsid Hexamer within 5.0Å range: probe atom residue distance (Å) B Occ A:F301 b:26.9 occ:0.25 F26 A:QNG301 0.0 26.9 0.2 F26 A:QNG301 0.2 26.8 0.5 C24 A:QNG301 1.4 26.0 0.5 C24 A:QNG301 1.4 26.1 0.2 C23 A:QNG301 2.3 25.9 0.5 C25 A:QNG301 2.4 27.3 0.2 C23 A:QNG301 2.4 26.3 0.2 C25 A:QNG301 2.5 27.3 0.5 N A:LYS70 3.2 30.6 1.0 CG A:LYS70 3.2 40.9 1.0 CB A:LEU69 3.3 35.4 1.0 CD1 A:ILE73 3.4 34.0 1.0 CG A:LEU69 3.4 36.8 1.0 C A:LEU69 3.4 33.7 1.0 O A:MET66 3.6 26.5 1.0 CA A:LYS70 3.6 32.6 1.0 C22 A:QNG301 3.6 27.8 0.5 C20 A:QNG301 3.7 28.4 0.2 C22 A:QNG301 3.7 27.9 0.2 C20 A:QNG301 3.7 28.6 0.5 CD2 A:LEU69 3.8 31.2 1.0 O A:LEU69 3.9 33.1 1.0 CA A:LEU69 4.0 33.2 1.0 CB A:LYS70 4.0 36.9 1.0 C21 A:QNG301 4.1 28.4 0.5 C21 A:QNG301 4.2 28.6 0.2 CD A:LYS70 4.4 44.3 1.0 CD1 A:LEU56 4.5 18.3 1.0 CG1 A:ILE73 4.5 28.7 1.0 F42 A:QNG301 4.6 33.7 0.5 F42 A:QNG301 4.6 33.6 0.2 F27 A:QNG301 4.7 30.9 0.5 C A:MET66 4.7 29.0 1.0 CD1 A:LEU69 4.8 40.0 1.0 F27 A:QNG301 4.8 30.1 0.2 N A:LEU69 4.9 28.3 1.0 C19 A:QNG301 4.9 29.3 0.2

Fluorine binding site 3 out of 60 in the Co-Crystal Structure of Gs-6207 Bound to Hiv-1 Capsid Hexamer


Mono view


Stereo pair view

A full contact list of Fluorine with other atoms in the F binding site number 3 of Co-Crystal Structure of Gs-6207 Bound to Hiv-1 Capsid Hexamer within 5.0Å range: probe atom residue distance (Å) B Occ A:F301 b:30.9 occ:0.51 F27 A:QNG301 0.0 30.9 0.5 F27 A:QNG301 0.1 30.1 0.2 C22 A:QNG301 1.3 27.9 0.2 C22 A:QNG301 1.4 27.8 0.5 C23 A:QNG301 2.3 26.3 0.2 C21 A:QNG301 2.3 28.6 0.2 C21 A:QNG301 2.4 28.4 0.5 C23 A:QNG301 2.4 25.9 0.5 F41 A:QNG301 2.6 36.0 0.5 F41 A:QNG301 2.6 35.5 0.2 CE A:MET66 3.1 42.0 1.0 CB A:MET66 3.2 30.3 1.0 O A:LEU56 3.2 26.5 1.0 CG A:MET66 3.3 36.3 1.0 F42 A:QNG301 3.4 33.6 0.2 F42 A:QNG301 3.4 33.7 0.5 C38 A:QNG301 3.5 33.8 0.5 C38 A:QNG301 3.5 33.7 0.2 C24 A:QNG301 3.6 26.1 0.2 C20 A:QNG301 3.6 28.4 0.2 C24 A:QNG301 3.7 26.0 0.5 C20 A:QNG301 3.7 28.6 0.5 C A:LEU56 3.8 25.3 1.0 SD A:MET66 3.9 39.9 1.0 C25 A:QNG301 4.1 27.3 0.2 CB A:LEU56 4.1 20.1 1.0 C25 A:QNG301 4.2 27.3 0.5 CA A:MET66 4.3 29.8 1.0 C37 A:QNG301 4.3 34.2 0.5 C37 A:QNG301 4.3 34.1 0.2 OD1 A:ASN57 4.5 37.7 1.0 N A:ASN57 4.5 23.6 1.0 CA A:LEU56 4.5 23.9 1.0 O A:MET66 4.6 26.5 1.0 CA A:ASN57 4.6 23.4 1.0 F26 A:QNG301 4.7 26.9 0.2 C32 A:QNG301 4.7 31.8 0.5 C A:MET66 4.7 29.0 1.0 C32 A:QNG301 4.8 31.9 0.2 F26 A:QNG301 4.8 26.8 0.5 C19 A:QNG301 4.9 29.3 0.2 OE1 A:GLN63 4.9 34.0 1.0 C19 A:QNG301 5.0 29.0 0.5

Fluorine binding site 4 out of 60 in the Co-Crystal Structure of Gs-6207 Bound to Hiv-1 Capsid Hexamer


Mono view


Stereo pair view

A full contact list of Fluorine with other atoms in the F binding site number 4 of Co-Crystal Structure of Gs-6207 Bound to Hiv-1 Capsid Hexamer within 5.0Å range: probe atom residue distance (Å) B Occ A:F301 b:30.1 occ:0.25 F27 A:QNG301 0.0 30.1 0.2 F27 A:QNG301 0.1 30.9 0.5 C22 A:QNG301 1.4 27.9 0.2 C22 A:QNG301 1.5 27.8 0.5 C21 A:QNG301 2.4 28.6 0.2 C23 A:QNG301 2.4 26.3 0.2 C21 A:QNG301 2.4 28.4 0.5 F41 A:QNG301 2.5 36.0 0.5 C23 A:QNG301 2.5 25.9 0.5 F41 A:QNG301 2.5 35.5 0.2 CE A:MET66 3.1 42.0 1.0 O A:LEU56 3.2 26.5 1.0 CB A:MET66 3.2 30.3 1.0 CG A:MET66 3.3 36.3 1.0 F42 A:QNG301 3.4 33.6 0.2 F42 A:QNG301 3.4 33.7 0.5 C38 A:QNG301 3.5 33.8 0.5 C38 A:QNG301 3.5 33.7 0.2 C20 A:QNG301 3.7 28.4 0.2 C24 A:QNG301 3.7 26.1 0.2 C20 A:QNG301 3.7 28.6 0.5 C24 A:QNG301 3.8 26.0 0.5 C A:LEU56 3.8 25.3 1.0 SD A:MET66 3.9 39.9 1.0 CB A:LEU56 4.1 20.1 1.0 C25 A:QNG301 4.2 27.3 0.2 C25 A:QNG301 4.2 27.3 0.5 C37 A:QNG301 4.3 34.2 0.5 C37 A:QNG301 4.3 34.1 0.2 CA A:MET66 4.3 29.8 1.0 OD1 A:ASN57 4.4 37.7 1.0 N A:ASN57 4.5 23.6 1.0 CA A:LEU56 4.5 23.9 1.0 CA A:ASN57 4.6 23.4 1.0 O A:MET66 4.7 26.5 1.0 C32 A:QNG301 4.7 31.8 0.5 C32 A:QNG301 4.7 31.9 0.2 C A:MET66 4.8 29.0 1.0 F26 A:QNG301 4.8 26.9 0.2 OE1 A:GLN63 4.8 34.0 1.0 F26 A:QNG301 4.9 26.8 0.5 C19 A:QNG301 5.0 29.3 0.2 NE2 A:GLN63 5.0 29.9 1.0 C19 A:QNG301 5.0 29.0 0.5

Fluorine binding site 5 out of 60 in the Co-Crystal Structure of Gs-6207 Bound to Hiv-1 Capsid Hexamer


Mono view


Stereo pair view

A full contact list of Fluorine with other atoms in the F binding site number 5 of Co-Crystal Structure of Gs-6207 Bound to Hiv-1 Capsid Hexamer within 5.0Å range: probe atom residue distance (Å) B Occ A:F301 b:36.0 occ:0.51 F41 A:QNG301 0.0 36.0 0.5 F41 A:QNG301 0.1 35.5 0.2 C38 A:QNG301 1.4 33.7 0.2 C38 A:QNG301 1.4 33.8 0.5 F42 A:QNG301 2.2 33.6 0.2 F42 A:QNG301 2.2 33.7 0.5 C37 A:QNG301 2.4 34.2 0.5 C37 A:QNG301 2.4 34.1 0.2 C32 A:QNG301 2.4 31.8 0.5 C32 A:QNG301 2.4 31.9 0.2 F27 A:QNG301 2.5 30.1 0.2 F27 A:QNG301 2.6 30.9 0.5 C22 A:QNG301 3.0 27.9 0.2 C22 A:QNG301 3.1 27.8 0.5 N33 A:QNG301 3.2 29.7 0.5 N33 A:QNG301 3.3 29.8 0.2 NE2 A:GLN63 3.4 29.9 1.0 C31 A:QNG301 3.4 33.2 0.5 C39 A:QNG301 3.4 33.7 0.5 C31 A:QNG301 3.4 32.9 0.2 C39 A:QNG301 3.5 33.8 0.2 C36 A:QNG301 3.5 33.9 0.5 C21 A:QNG301 3.5 28.6 0.2 C36 A:QNG301 3.5 33.8 0.2 C30 A:QNG301 3.6 29.2 0.2 C21 A:QNG301 3.6 28.4 0.5 C30 A:QNG301 3.6 29.1 0.5 CB A:MET66 3.7 30.3 1.0 C23 A:QNG301 3.9 26.3 0.2 C23 A:QNG301 4.0 25.9 0.5 C28 A:QNG301 4.0 28.5 0.2 C28 A:QNG301 4.0 28.5 0.5 CD A:GLN63 4.2 35.8 1.0 CG A:MET66 4.3 36.3 1.0 OE1 A:GLN63 4.4 34.0 1.0 O29 A:QNG301 4.4 28.4 0.2 N34 A:QNG301 4.4 31.3 0.5 O29 A:QNG301 4.4 28.4 0.5 N34 A:QNG301 4.5 31.0 0.2 OD1 A:ASN57 4.5 37.7 1.0 C35 A:QNG301 4.5 31.9 0.5 C35 A:QNG301 4.6 32.0 0.2 N43 A:QNG301 4.6 29.0 0.2 C20 A:QNG301 4.6 28.4 0.2 N43 A:QNG301 4.6 28.7 0.5 C20 A:QNG301 4.7 28.6 0.5 C24 A:QNG301 4.9 26.1 0.2 CA A:MET66 4.9 29.8 1.0 C A:MET66 4.9 29.0 1.0 O A:MET66 5.0 26.5 1.0 NZ A:LYS70 5.0 47.8 1.0 C24 A:QNG301 5.0 26.0 0.5

Fluorine binding site 6 out of 60 in the Co-Crystal Structure of Gs-6207 Bound to Hiv-1 Capsid Hexamer


Mono view


Stereo pair view

A full contact list of Fluorine with other atoms in the F binding site number 6 of Co-Crystal Structure of Gs-6207 Bound to Hiv-1 Capsid Hexamer within 5.0Å range: probe atom residue distance (Å) B Occ A:F301 b:35.5 occ:0.25 F41 A:QNG301 0.0 35.5 0.2 F41 A:QNG301 0.1 36.0 0.5 C38 A:QNG301 1.4 33.7 0.2 C38 A:QNG301 1.4 33.8 0.5 F42 A:QNG301 2.2 33.6 0.2 F42 A:QNG301 2.3 33.7 0.5 C37 A:QNG301 2.3 34.2 0.5 C32 A:QNG301 2.4 31.8 0.5 C37 A:QNG301 2.4 34.1 0.2 C32 A:QNG301 2.4 31.9 0.2 F27 A:QNG301 2.5 30.1 0.2 F27 A:QNG301 2.6 30.9 0.5 C22 A:QNG301 3.1 27.9 0.2 C22 A:QNG301 3.2 27.8 0.5 N33 A:QNG301 3.2 29.7 0.5 N33 A:QNG301 3.2 29.8 0.2 NE2 A:GLN63 3.3 29.9 1.0 C31 A:QNG301 3.4 33.2 0.5 C39 A:QNG301 3.4 33.7 0.5 C31 A:QNG301 3.4 32.9 0.2 C39 A:QNG301 3.4 33.8 0.2 C36 A:QNG301 3.5 33.9 0.5 C36 A:QNG301 3.5 33.8 0.2 C30 A:QNG301 3.5 29.2 0.2 C30 A:QNG301 3.6 29.1 0.5 C21 A:QNG301 3.6 28.6 0.2 C21 A:QNG301 3.6 28.4 0.5 CB A:MET66 3.7 30.3 1.0 C23 A:QNG301 4.0 26.3 0.2 C28 A:QNG301 4.0 28.5 0.2 C28 A:QNG301 4.0 28.5 0.5 C23 A:QNG301 4.0 25.9 0.5 CD A:GLN63 4.2 35.8 1.0 OE1 A:GLN63 4.3 34.0 1.0 CG A:MET66 4.4 36.3 1.0 N34 A:QNG301 4.4 31.3 0.5 N34 A:QNG301 4.4 31.0 0.2 O29 A:QNG301 4.4 28.4 0.2 O29 A:QNG301 4.5 28.4 0.5 C35 A:QNG301 4.5 31.9 0.5 OD1 A:ASN57 4.5 37.7 1.0 C35 A:QNG301 4.5 32.0 0.2 N43 A:QNG301 4.6 29.0 0.2 N43 A:QNG301 4.7 28.7 0.5 C20 A:QNG301 4.7 28.4 0.2 C20 A:QNG301 4.7 28.6 0.5 CA A:MET66 4.9 29.8 1.0 C A:MET66 4.9 29.0 1.0 C24 A:QNG301 5.0 26.1 0.2 NZ A:LYS70 5.0 47.8 1.0

Fluorine binding site 7 out of 60 in the Co-Crystal Structure of Gs-6207 Bound to Hiv-1 Capsid Hexamer


Mono view


Stereo pair view

A full contact list of Fluorine with other atoms in the F binding site number 7 of Co-Crystal Structure of Gs-6207 Bound to Hiv-1 Capsid Hexamer within 5.0Å range: probe atom residue distance (Å) B Occ A:F301 b:33.7 occ:0.51 F42 A:QNG301 0.0 33.7 0.5 F42 A:QNG301 0.1 33.6 0.2 C38 A:QNG301 1.4 33.8 0.5 C38 A:QNG301 1.4 33.7 0.2 F41 A:QNG301 2.2 36.0 0.5 F41 A:QNG301 2.3 35.5 0.2 C37 A:QNG301 2.4 34.2 0.5 C37 A:QNG301 2.4 34.1 0.2 C32 A:QNG301 2.4 31.9 0.2 C32 A:QNG301 2.4 31.8 0.5 CE A:LYS70 3.0 46.0 1.0 C22 A:QNG301 3.1 27.9 0.2 C22 A:QNG301 3.1 27.8 0.5 CD A:LYS70 3.2 44.3 1.0 NZ A:LYS70 3.3 47.8 1.0 C23 A:QNG301 3.3 26.3 0.2 O29 A:QNG301 3.3 28.4 0.2 C36 A:QNG301 3.3 33.8 0.2 C23 A:QNG301 3.3 25.9 0.5 C36 A:QNG301 3.3 33.9 0.5 O29 A:QNG301 3.3 28.4 0.5 C31 A:QNG301 3.3 32.9 0.2 C31 A:QNG301 3.3 33.2 0.5 N33 A:QNG301 3.4 29.8 0.2 N33 A:QNG301 3.4 29.7 0.5 C21 A:QNG301 3.4 28.6 0.2 F27 A:QNG301 3.4 30.9 0.5 CG A:LYS70 3.4 40.9 1.0 C21 A:QNG301 3.4 28.4 0.5 F27 A:QNG301 3.4 30.1 0.2 C28 A:QNG301 3.5 28.5 0.2 C28 A:QNG301 3.5 28.5 0.5 C24 A:QNG301 3.7 26.1 0.2 C30 A:QNG301 3.8 29.2 0.2 C24 A:QNG301 3.8 26.0 0.5 C30 A:QNG301 3.8 29.1 0.5 C20 A:QNG301 3.9 28.4 0.2 C39 A:QNG301 3.9 33.7 0.5 O A:MET66 3.9 26.5 1.0 C39 A:QNG301 3.9 33.8 0.2 C20 A:QNG301 3.9 28.6 0.5 C25 A:QNG301 4.0 27.3 0.2 C25 A:QNG301 4.1 27.3 0.5 N43 A:QNG301 4.2 29.0 0.2 N43 A:QNG301 4.2 28.7 0.5 C A:MET66 4.3 29.0 1.0 CB A:MET66 4.3 30.3 1.0 C35 A:QNG301 4.4 32.0 0.2 N34 A:QNG301 4.5 31.0 0.2 C35 A:QNG301 4.5 31.9 0.5 N34 A:QNG301 4.5 31.3 0.5 F26 A:QNG301 4.6 26.9 0.2 F26 A:QNG301 4.6 26.8 0.5 CB A:LYS70 4.6 36.9 1.0 C01 A:QNG301 4.7 29.6 0.2 C01 A:QNG301 4.7 29.8 0.5 N A:GLN67 4.8 28.4 1.0 OE1 A:GLN67 4.9 28.2 1.0 C19 A:QNG301 4.9 29.3 0.2 CA A:MET66 4.9 29.8 1.0 CA A:GLN67 4.9 32.1 1.0 C19 A:QNG301 5.0 29.0 0.5

Fluorine binding site 8 out of 60 in the Co-Crystal Structure of Gs-6207 Bound to Hiv-1 Capsid Hexamer


Mono view


Stereo pair view

A full contact list of Fluorine with other atoms in the F binding site number 8 of Co-Crystal Structure of Gs-6207 Bound to Hiv-1 Capsid Hexamer within 5.0Å range: probe atom residue distance (Å) B Occ A:F301 b:33.6 occ:0.25 F42 A:QNG301 0.0 33.6 0.2 F42 A:QNG301 0.1 33.7 0.5 C38 A:QNG301 1.3 33.8 0.5 C38 A:QNG301 1.4 33.7 0.2 F41 A:QNG301 2.2 36.0 0.5 F41 A:QNG301 2.2 35.5 0.2 C37 A:QNG301 2.3 34.2 0.5 C37 A:QNG301 2.4 34.1 0.2 C32 A:QNG301 2.4 31.9 0.2 C32 A:QNG301 2.4 31.8 0.5 C22 A:QNG301 3.0 27.9 0.2 C22 A:QNG301 3.1 27.8 0.5 CE A:LYS70 3.1 46.0 1.0 CD A:LYS70 3.2 44.3 1.0 C23 A:QNG301 3.2 26.3 0.2 C36 A:QNG301 3.3 33.8 0.2 C23 A:QNG301 3.3 25.9 0.5 C36 A:QNG301 3.3 33.9 0.5 C31 A:QNG301 3.3 32.9 0.2 NZ A:LYS70 3.3 47.8 1.0 O29 A:QNG301 3.3 28.4 0.2 C31 A:QNG301 3.3 33.2 0.5 O29 A:QNG301 3.3 28.4 0.5 N33 A:QNG301 3.4 29.8 0.2 F27 A:QNG301 3.4 30.9 0.5 N33 A:QNG301 3.4 29.7 0.5 C21 A:QNG301 3.4 28.6 0.2 F27 A:QNG301 3.4 30.1 0.2 C21 A:QNG301 3.4 28.4 0.5 CG A:LYS70 3.5 40.9 1.0 C28 A:QNG301 3.5 28.5 0.2 C28 A:QNG301 3.5 28.5 0.5 C24 A:QNG301 3.7 26.1 0.2 C30 A:QNG301 3.8 29.2 0.2 C24 A:QNG301 3.8 26.0 0.5 C30 A:QNG301 3.8 29.1 0.5 C39 A:QNG301 3.8 33.7 0.5 O A:MET66 3.9 26.5 1.0 C39 A:QNG301 3.9 33.8 0.2 C20 A:QNG301 3.9 28.4 0.2 C20 A:QNG301 3.9 28.6 0.5 C25 A:QNG301 4.0 27.3 0.2 C25 A:QNG301 4.1 27.3 0.5 N43 A:QNG301 4.2 29.0 0.2 CB A:MET66 4.2 30.3 1.0 N43 A:QNG301 4.3 28.7 0.5 C A:MET66 4.3 29.0 1.0 C35 A:QNG301 4.5 32.0 0.2 N34 A:QNG301 4.5 31.0 0.2 C35 A:QNG301 4.5 31.9 0.5 N34 A:QNG301 4.5 31.3 0.5 F26 A:QNG301 4.6 26.9 0.2 F26 A:QNG301 4.6 26.8 0.5 CB A:LYS70 4.7 36.9 1.0 C01 A:QNG301 4.7 29.6 0.2 C01 A:QNG301 4.8 29.8 0.5 N A:GLN67 4.8 28.4 1.0 CA A:MET66 4.9 29.8 1.0 OE1 A:GLN67 4.9 28.2 1.0 C19 A:QNG301 4.9 29.3 0.2 CA A:GLN67 4.9 32.1 1.0 C19 A:QNG301 5.0 29.0 0.5

Fluorine binding site 9 out of 60 in the Co-Crystal Structure of Gs-6207 Bound to Hiv-1 Capsid Hexamer


Mono view


Stereo pair view

A full contact list of Fluorine with other atoms in the F binding site number 9 of Co-Crystal Structure of Gs-6207 Bound to Hiv-1 Capsid Hexamer within 5.0Å range: probe atom residue distance (Å) B Occ A:F301 b:32.8 occ:0.51 F52 A:QNG301 0.0 32.8 0.5 F52 A:QNG301 0.9 32.1 0.2 C40 A:QNG301 1.4 31.9 0.5 C40 A:QNG301 1.5 32.0 0.2 F53 A:QNG301 1.8 33.1 0.2 F64 A:QNG301 2.2 31.4 0.5 F53 A:QNG301 2.2 33.9 0.5 C35 A:QNG301 2.3 31.9 0.5 C35 A:QNG301 2.3 32.0 0.2 F64 A:QNG301 2.7 31.6 0.2 C31 A:QNG301 2.9 33.2 0.5 C31 A:QNG301 2.9 32.9 0.2 C36 A:QNG301 3.4 33.9 0.5 C36 A:QNG301 3.5 33.8 0.2 N34 A:QNG301 3.5 31.0 0.2 N34 A:QNG301 3.5 31.3 0.5 C39 A:QNG301 4.1 33.8 0.2 C39 A:QNG301 4.2 33.7 0.5 C32 A:QNG301 4.2 31.9 0.2 O A:HOH413 4.2 39.6 1.0 C32 A:QNG301 4.2 31.8 0.5 N33 A:QNG301 4.4 29.8 0.2 N33 A:QNG301 4.5 29.7 0.5 C37 A:QNG301 4.8 34.1 0.2 C37 A:QNG301 4.8 34.2 0.5

Fluorine binding site 10 out of 60 in the Co-Crystal Structure of Gs-6207 Bound to Hiv-1 Capsid Hexamer


Mono view


Stereo pair view

A full contact list of Fluorine with other atoms in the F binding site number 10 of Co-Crystal Structure of Gs-6207 Bound to Hiv-1 Capsid Hexamer within 5.0Å range: probe atom residue distance (Å) B Occ A:F301 b:32.1 occ:0.25 F52 A:QNG301 0.0 32.1 0.2 F52 A:QNG301 0.9 32.8 0.5 C40 A:QNG301 1.4 32.0 0.2 C40 A:QNG301 1.4 31.9 0.5 F64 A:QNG301 1.7 31.4 0.5 F64 A:QNG301 2.2 31.6 0.2 F53 A:QNG301 2.2 33.1 0.2 C35 A:QNG301 2.4 32.0 0.2 C35 A:QNG301 2.4 31.9 0.5 F53 A:QNG301 2.6 33.9 0.5 C31 A:QNG301 2.9 32.9 0.2 C31 A:QNG301 2.9 33.2 0.5 C36 A:QNG301 3.2 33.9 0.5 C36 A:QNG301 3.2 33.8 0.2 O A:HOH413 3.4 39.6 1.0 N34 A:QNG301 3.7 31.0 0.2 N34 A:QNG301 3.7 31.3 0.5 C39 A:QNG301 4.1 33.8 0.2 C39 A:QNG301 4.1 33.7 0.5 C32 A:QNG301 4.2 31.9 0.2 C32 A:QNG301 4.3 31.8 0.5 N33 A:QNG301 4.6 29.8 0.2 N33 A:QNG301 4.6 29.7 0.5 C37 A:QNG301 4.7 34.1 0.2 C37 A:QNG301 4.7 34.2 0.5 OE1 A:GLN67 4.8 28.2 1.0 NZ A:LYS70 5.0 47.8 1.0

S.M.Bester, G.Wei, H.Zhao, D.Adu-Ampratwum, N.Iqbal, V.V.Courouble, A.C.Francis, A.S.Annamalai, P.K.Singh, N.Shkriabai, P.Van Blerkom, J.Morrison, E.M.Poeschla, A.N.Engelman, G.B.Melikyan, P.R.Griffin, J.R.Fuchs, F.J.Asturias, M.Kvaratskhelia. Structural and Mechanistic Bases For A Potent Hiv-1 Capsid Inhibitor. Science V. 370 360 2020.
ISSN: ESSN 1095-9203
PubMed: 33060363
DOI: 10.1126/SCIENCE.ABB4808