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Fluorine in PDB 6vnv: Crystal Structure of TYK2 Kinase with Compound 14Enzymatic activity of Crystal Structure of TYK2 Kinase with Compound 14
All present enzymatic activity of Crystal Structure of TYK2 Kinase with Compound 14:
2.7.10.2; Protein crystallography data
The structure of Crystal Structure of TYK2 Kinase with Compound 14, PDB code: 6vnv
was solved by
F.F.Vajdos,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Fluorine Binding Sites:
The binding sites of Fluorine atom in the Crystal Structure of TYK2 Kinase with Compound 14
(pdb code 6vnv). This binding sites where shown within
5.0 Angstroms radius around Fluorine atom.
In total only one binding site of Fluorine was determined in the Crystal Structure of TYK2 Kinase with Compound 14, PDB code: 6vnv: Fluorine binding site 1 out of 1 in 6vnvGo back to Fluorine Binding Sites List in 6vnv
Fluorine binding site 1 out
of 1 in the Crystal Structure of TYK2 Kinase with Compound 14
Mono view Stereo pair view
Reference:
A.Fensome,
C.M.Ambler,
E.Arnold,
M.E.Banker,
J.D.Clark,
M.E.Dowty,
I.V.Efremov,
A.Flick,
B.S.Gerstenberger,
R.Gifford,
A.Gopalsamy,
M.Hegen,
J.Jussif,
D.C.Limburg,
T.H.Lin,
B.S.Pierce,
R.Sharma,
J.I.Trujillo,
F.F.Vajdos,
F.Vincent,
Z.-K.Wan,
L.Xing,
X.Yang,
X.Yang.
Design and Optimization of A Series of 4-(3-Azabicyclo[3.1.0]Hexan-3-Yl)Pyrimidin-2-Amines: Dual Inhibitors of TYK2 and JAK1 Bioorg.Med.Chem. 2020.
Page generated: Sun Dec 13 13:24:24 2020
ISSN: ESSN 1464-3391 DOI: 10.1016/J.BMC.2020.115481 |
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