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Fluorine in PDB 6w3k: Structure of Unphosphorylated Human IRE1 Bound to G-9807Enzymatic activity of Structure of Unphosphorylated Human IRE1 Bound to G-9807
All present enzymatic activity of Structure of Unphosphorylated Human IRE1 Bound to G-9807:
2.7.11.1; Protein crystallography data
The structure of Structure of Unphosphorylated Human IRE1 Bound to G-9807, PDB code: 6w3k
was solved by
A.Lammens,
W.Wang,
E.Ferri,
J.Rudolph,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Fluorine Binding Sites:
The binding sites of Fluorine atom in the Structure of Unphosphorylated Human IRE1 Bound to G-9807
(pdb code 6w3k). This binding sites where shown within
5.0 Angstroms radius around Fluorine atom.
In total 2 binding sites of Fluorine where determined in the Structure of Unphosphorylated Human IRE1 Bound to G-9807, PDB code: 6w3k: Jump to Fluorine binding site number: 1; 2; Fluorine binding site 1 out of 2 in 6w3kGo back to Fluorine Binding Sites List in 6w3k
Fluorine binding site 1 out
of 2 in the Structure of Unphosphorylated Human IRE1 Bound to G-9807
Mono view Stereo pair view
Fluorine binding site 2 out of 2 in 6w3kGo back to Fluorine Binding Sites List in 6w3k
Fluorine binding site 2 out
of 2 in the Structure of Unphosphorylated Human IRE1 Bound to G-9807
Mono view Stereo pair view
Reference:
E.Ferri,
A.Le Thomas,
H.Ackerly Wallweber,
E.S.Day,
B.T.Walters,
S.E.Kaufman,
M.-G.Braun,
K.R.Clark,
M.H.Beresini,
K.Mortara,
Y.-C.A.Chen,
B.Canter,
W.Phung,
P.S.Liu,
A.Lammens,
A.Ashkenazi,
J.Rudolph,
W.Wang.
Activation of the IRE1 Rnase Through Remodeling of the Kinase Front Pocket By Atp-Competitive Ligands Nat Commun 2020.
Page generated: Sun Dec 13 13:27:20 2020
ISSN: ESSN 2041-1723 DOI: 10.1038/S41467-020-19974-5 |
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