Fluorine in PDB 6w5x: Crystal Structure of Human Polymerase Eta Complexed with N7- Benzylguanine and Dctp*

Enzymatic activity of Crystal Structure of Human Polymerase Eta Complexed with N7- Benzylguanine and Dctp*

All present enzymatic activity of Crystal Structure of Human Polymerase Eta Complexed with N7- Benzylguanine and Dctp*:
2.7.7.7;

Protein crystallography data

The structure of Crystal Structure of Human Polymerase Eta Complexed with N7- Benzylguanine and Dctp*, PDB code: 6w5x was solved by H.Jung, S.Lee, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å) 49.16 / 2.59
Space group P 61
Cell size a, b, c (Å), α, β, γ (°) 98.329, 98.329, 81.312, 90, 90, 120
R / Rfree (%) 18.4 / 25.6

Other elements in 6w5x:

The structure of Crystal Structure of Human Polymerase Eta Complexed with N7- Benzylguanine and Dctp* also contains other interesting chemical elements:

Manganese (Mn) 2 atoms

Fluorine Binding Sites:

The binding sites of Fluorine atom in the Crystal Structure of Human Polymerase Eta Complexed with N7- Benzylguanine and Dctp* (pdb code 6w5x). This binding sites where shown within 5.0 Angstroms radius around Fluorine atom.
In total only one binding site of Fluorine was determined in the Crystal Structure of Human Polymerase Eta Complexed with N7- Benzylguanine and Dctp*, PDB code: 6w5x:

Fluorine binding site 1 out of 1 in 6w5x

Go back to Fluorine Binding Sites List in 6w5x
Fluorine binding site 1 out of 1 in the Crystal Structure of Human Polymerase Eta Complexed with N7- Benzylguanine and Dctp*


Mono view


Stereo pair view

A full contact list of Fluorine with other atoms in the F binding site number 1 of Crystal Structure of Human Polymerase Eta Complexed with N7- Benzylguanine and Dctp* within 5.0Å range:
probe atom residue distance (Å) B Occ
T:F4

b:80.0
occ:1.00
 F1' T:7BG4 0.0 80.0 1.0
C2' T:7BG4 1.2 70.7 1.0
C3' T:7BG4 2.1 67.8 1.0
C1' T:7BG4 2.2 70.2 1.0
N9 T:7BG4 2.5 76.1 1.0
C8 T:7BG4 2.9 81.6 1.0
C4' T:7BG4 3.0 76.8 1.0
C5' T:7BG4 3.1 85.8 1.0
O4' T:7BG4 3.2 72.8 1.0
C6 T:DC5 3.2 61.0 1.0
O3' T:7BG4 3.2 66.4 1.0
P T:DC5 3.3 58.2 1.0
C4 T:7BG4 3.3 70.8 1.0
OP2 T:DC5 3.3 67.2 1.0
O5' T:DC5 3.3 64.6 1.0
ND2 A:ASN324 3.4 67.0 1.0
C5 T:DC5 3.5 61.7 1.0
N7 T:7BG4 3.9 75.3 1.0
N3 T:7BG4 3.9 64.4 1.0
O4' T:DC5 3.9 65.0 1.0
N1 T:DC5 4.0 57.6 1.0
C5 T:7BG4 4.0 72.6 1.0
C5' T:DC5 4.0 66.0 1.0
C1' T:DC5 4.5 63.2 1.0
O5' T:7BG4 4.5 97.9 1.0
CG A:ASN324 4.6 66.9 1.0
C4 T:DC5 4.6 65.2 1.0
C4' T:DC5 4.6 62.9 1.0
OP1 T:DC5 4.7 65.0 1.0
C12 T:7BG4 4.7 92.3 1.0
C2' T:DC5 4.8 60.1 1.0
OE1 A:GLN38 4.8 57.7 1.0
OP2 T:7BG4 4.9 100.6 1.0
C2 T:DC5 5.0 60.0 1.0
CB A:ASN324 5.0 62.9 1.0

Reference:

H.Jung, S.Lee. Crystal Structure of Human Polymerase Eta Complexed with N7-Benzylguanine and Dctp* To Be Published.
Page generated: Sat Apr 3 15:03:41 2021

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