Fluorine in PDB 6x14: Inward-Facing State of the Glutamate Transporter Homologue Gltph in Complex with Tfb-Tboa
Fluorine Binding Sites:
The binding sites of Fluorine atom in the Inward-Facing State of the Glutamate Transporter Homologue Gltph in Complex with Tfb-Tboa
(pdb code 6x14). This binding sites where shown within
5.0 Angstroms radius around Fluorine atom.
In total 9 binding sites of Fluorine where determined in the
Inward-Facing State of the Glutamate Transporter Homologue Gltph in Complex with Tfb-Tboa, PDB code: 6x14:
Jump to Fluorine binding site number:
1;
2;
3;
4;
5;
6;
7;
8;
9;
Fluorine binding site 1 out
of 9 in 6x14
Go back to
Fluorine Binding Sites List in 6x14
Fluorine binding site 1 out
of 9 in the Inward-Facing State of the Glutamate Transporter Homologue Gltph in Complex with Tfb-Tboa
Mono view
Stereo pair view
|
A full contact list of Fluorine with other atoms in the F binding
site number 1 of Inward-Facing State of the Glutamate Transporter Homologue Gltph in Complex with Tfb-Tboa within 5.0Å range:
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
A:F501
b:52.0
occ:1.00
|
F2
|
A:7O9501
|
0.0
|
52.0
|
1.0
|
C13
|
A:7O9501
|
1.4
|
52.0
|
1.0
|
F
|
A:7O9501
|
2.2
|
52.0
|
1.0
|
F1
|
A:7O9501
|
2.2
|
52.0
|
1.0
|
C12
|
A:7O9501
|
2.3
|
52.0
|
1.0
|
C14
|
A:7O9501
|
2.8
|
52.0
|
1.0
|
CZ
|
A:PHE50
|
3.1
|
35.6
|
1.0
|
CD1
|
A:ILE16
|
3.3
|
48.0
|
1.0
|
C11
|
A:7O9501
|
3.5
|
52.0
|
1.0
|
CE2
|
A:PHE50
|
3.7
|
35.6
|
1.0
|
CB
|
A:ALA205
|
3.9
|
40.3
|
1.0
|
C15
|
A:7O9501
|
4.1
|
52.0
|
1.0
|
CE1
|
A:PHE50
|
4.2
|
35.6
|
1.0
|
SD
|
A:MET202
|
4.5
|
41.5
|
1.0
|
C10
|
A:7O9501
|
4.6
|
52.0
|
1.0
|
CG1
|
A:ILE16
|
4.7
|
48.0
|
1.0
|
CD1
|
A:LEU54
|
4.7
|
33.2
|
1.0
|
CD2
|
A:LEU387
|
4.7
|
42.9
|
1.0
|
CE
|
A:MET202
|
4.8
|
41.5
|
1.0
|
C9
|
A:7O9501
|
4.9
|
52.0
|
1.0
|
|
Fluorine binding site 2 out
of 9 in 6x14
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Fluorine Binding Sites List in 6x14
Fluorine binding site 2 out
of 9 in the Inward-Facing State of the Glutamate Transporter Homologue Gltph in Complex with Tfb-Tboa
Mono view
Stereo pair view
|
A full contact list of Fluorine with other atoms in the F binding
site number 2 of Inward-Facing State of the Glutamate Transporter Homologue Gltph in Complex with Tfb-Tboa within 5.0Å range:
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
A:F501
b:52.0
occ:1.00
|
F
|
A:7O9501
|
0.0
|
52.0
|
1.0
|
C13
|
A:7O9501
|
1.4
|
52.0
|
1.0
|
F2
|
A:7O9501
|
2.2
|
52.0
|
1.0
|
F1
|
A:7O9501
|
2.2
|
52.0
|
1.0
|
C12
|
A:7O9501
|
2.4
|
52.0
|
1.0
|
C11
|
A:7O9501
|
2.7
|
52.0
|
1.0
|
CD1
|
A:ILE16
|
3.3
|
48.0
|
1.0
|
CD2
|
A:LEU387
|
3.3
|
42.9
|
1.0
|
C14
|
A:7O9501
|
3.6
|
52.0
|
1.0
|
CG
|
A:LEU387
|
3.9
|
42.9
|
1.0
|
C10
|
A:7O9501
|
4.1
|
52.0
|
1.0
|
CG1
|
A:ILE16
|
4.3
|
48.0
|
1.0
|
CG2
|
A:VAL209
|
4.4
|
39.6
|
1.0
|
C15
|
A:7O9501
|
4.7
|
52.0
|
1.0
|
CZ
|
A:PHE50
|
4.7
|
35.6
|
1.0
|
CE2
|
A:PHE50
|
4.8
|
35.6
|
1.0
|
CB
|
A:VAL209
|
4.8
|
39.6
|
1.0
|
CB
|
A:LEU387
|
4.9
|
42.9
|
1.0
|
C9
|
A:7O9501
|
4.9
|
52.0
|
1.0
|
CD1
|
A:LEU387
|
5.0
|
42.9
|
1.0
|
|
Fluorine binding site 3 out
of 9 in 6x14
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Fluorine Binding Sites List in 6x14
Fluorine binding site 3 out
of 9 in the Inward-Facing State of the Glutamate Transporter Homologue Gltph in Complex with Tfb-Tboa
Mono view
Stereo pair view
|
A full contact list of Fluorine with other atoms in the F binding
site number 3 of Inward-Facing State of the Glutamate Transporter Homologue Gltph in Complex with Tfb-Tboa within 5.0Å range:
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
A:F501
b:52.0
occ:1.00
|
F1
|
A:7O9501
|
0.0
|
52.0
|
1.0
|
C13
|
A:7O9501
|
1.4
|
52.0
|
1.0
|
F2
|
A:7O9501
|
2.2
|
52.0
|
1.0
|
F
|
A:7O9501
|
2.2
|
52.0
|
1.0
|
C12
|
A:7O9501
|
2.4
|
52.0
|
1.0
|
C14
|
A:7O9501
|
3.0
|
52.0
|
1.0
|
C11
|
A:7O9501
|
3.3
|
52.0
|
1.0
|
CD2
|
A:LEU387
|
3.3
|
42.9
|
1.0
|
CB
|
A:ALA360
|
3.9
|
39.4
|
1.0
|
CD1
|
A:LEU54
|
4.0
|
33.2
|
1.0
|
CG
|
A:LEU387
|
4.1
|
42.9
|
1.0
|
CZ
|
A:PHE50
|
4.1
|
35.6
|
1.0
|
CE2
|
A:PHE50
|
4.2
|
35.6
|
1.0
|
OH
|
A:TYR383
|
4.2
|
44.6
|
1.0
|
C15
|
A:7O9501
|
4.3
|
52.0
|
1.0
|
CD1
|
A:LEU387
|
4.5
|
42.9
|
1.0
|
C10
|
A:7O9501
|
4.5
|
52.0
|
1.0
|
CA
|
A:ALA360
|
4.9
|
39.4
|
1.0
|
C9
|
A:7O9501
|
4.9
|
52.0
|
1.0
|
CZ
|
A:TYR383
|
5.0
|
44.6
|
1.0
|
|
Fluorine binding site 4 out
of 9 in 6x14
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Fluorine Binding Sites List in 6x14
Fluorine binding site 4 out
of 9 in the Inward-Facing State of the Glutamate Transporter Homologue Gltph in Complex with Tfb-Tboa
Mono view
Stereo pair view
|
A full contact list of Fluorine with other atoms in the F binding
site number 4 of Inward-Facing State of the Glutamate Transporter Homologue Gltph in Complex with Tfb-Tboa within 5.0Å range:
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
B:F501
b:52.0
occ:1.00
|
F2
|
B:7O9501
|
0.0
|
52.0
|
1.0
|
C13
|
B:7O9501
|
1.4
|
52.0
|
1.0
|
F
|
B:7O9501
|
2.2
|
52.0
|
1.0
|
F1
|
B:7O9501
|
2.2
|
52.0
|
1.0
|
C12
|
B:7O9501
|
2.3
|
52.0
|
1.0
|
C14
|
B:7O9501
|
2.8
|
52.0
|
1.0
|
CZ
|
B:PHE50
|
3.1
|
35.6
|
1.0
|
CD1
|
B:ILE16
|
3.3
|
48.0
|
1.0
|
C11
|
B:7O9501
|
3.5
|
52.0
|
1.0
|
CE2
|
B:PHE50
|
3.7
|
35.6
|
1.0
|
CB
|
B:ALA205
|
3.9
|
40.3
|
1.0
|
C15
|
B:7O9501
|
4.1
|
52.0
|
1.0
|
CE1
|
B:PHE50
|
4.2
|
35.6
|
1.0
|
SD
|
B:MET202
|
4.5
|
41.5
|
1.0
|
C10
|
B:7O9501
|
4.6
|
52.0
|
1.0
|
CG1
|
B:ILE16
|
4.7
|
48.0
|
1.0
|
CD1
|
B:LEU54
|
4.7
|
33.2
|
1.0
|
CD2
|
B:LEU387
|
4.7
|
42.9
|
1.0
|
CE
|
B:MET202
|
4.8
|
41.5
|
1.0
|
C9
|
B:7O9501
|
4.9
|
52.0
|
1.0
|
|
Fluorine binding site 5 out
of 9 in 6x14
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Fluorine Binding Sites List in 6x14
Fluorine binding site 5 out
of 9 in the Inward-Facing State of the Glutamate Transporter Homologue Gltph in Complex with Tfb-Tboa
Mono view
Stereo pair view
|
A full contact list of Fluorine with other atoms in the F binding
site number 5 of Inward-Facing State of the Glutamate Transporter Homologue Gltph in Complex with Tfb-Tboa within 5.0Å range:
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
B:F501
b:52.0
occ:1.00
|
F
|
B:7O9501
|
0.0
|
52.0
|
1.0
|
C13
|
B:7O9501
|
1.4
|
52.0
|
1.0
|
F2
|
B:7O9501
|
2.2
|
52.0
|
1.0
|
F1
|
B:7O9501
|
2.2
|
52.0
|
1.0
|
C12
|
B:7O9501
|
2.4
|
52.0
|
1.0
|
C11
|
B:7O9501
|
2.7
|
52.0
|
1.0
|
CD1
|
B:ILE16
|
3.3
|
48.0
|
1.0
|
CD2
|
B:LEU387
|
3.3
|
42.9
|
1.0
|
C14
|
B:7O9501
|
3.6
|
52.0
|
1.0
|
CG
|
B:LEU387
|
3.9
|
42.9
|
1.0
|
C10
|
B:7O9501
|
4.1
|
52.0
|
1.0
|
CG1
|
B:ILE16
|
4.3
|
48.0
|
1.0
|
CG2
|
B:VAL209
|
4.4
|
39.6
|
1.0
|
C15
|
B:7O9501
|
4.7
|
52.0
|
1.0
|
CZ
|
B:PHE50
|
4.7
|
35.6
|
1.0
|
CE2
|
B:PHE50
|
4.8
|
35.6
|
1.0
|
CB
|
B:VAL209
|
4.8
|
39.6
|
1.0
|
CB
|
B:LEU387
|
4.9
|
42.9
|
1.0
|
C9
|
B:7O9501
|
4.9
|
52.0
|
1.0
|
CD1
|
B:LEU387
|
5.0
|
42.9
|
1.0
|
|
Fluorine binding site 6 out
of 9 in 6x14
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Fluorine Binding Sites List in 6x14
Fluorine binding site 6 out
of 9 in the Inward-Facing State of the Glutamate Transporter Homologue Gltph in Complex with Tfb-Tboa
Mono view
Stereo pair view
|
A full contact list of Fluorine with other atoms in the F binding
site number 6 of Inward-Facing State of the Glutamate Transporter Homologue Gltph in Complex with Tfb-Tboa within 5.0Å range:
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
B:F501
b:52.0
occ:1.00
|
F1
|
B:7O9501
|
0.0
|
52.0
|
1.0
|
C13
|
B:7O9501
|
1.4
|
52.0
|
1.0
|
F2
|
B:7O9501
|
2.2
|
52.0
|
1.0
|
F
|
B:7O9501
|
2.2
|
52.0
|
1.0
|
C12
|
B:7O9501
|
2.4
|
52.0
|
1.0
|
C14
|
B:7O9501
|
3.0
|
52.0
|
1.0
|
C11
|
B:7O9501
|
3.3
|
52.0
|
1.0
|
CD2
|
B:LEU387
|
3.3
|
42.9
|
1.0
|
CB
|
B:ALA360
|
3.9
|
39.4
|
1.0
|
CD1
|
B:LEU54
|
4.0
|
33.2
|
1.0
|
CG
|
B:LEU387
|
4.1
|
42.9
|
1.0
|
CZ
|
B:PHE50
|
4.1
|
35.6
|
1.0
|
CE2
|
B:PHE50
|
4.2
|
35.6
|
1.0
|
OH
|
B:TYR383
|
4.2
|
44.6
|
1.0
|
C15
|
B:7O9501
|
4.3
|
52.0
|
1.0
|
CD1
|
B:LEU387
|
4.5
|
42.9
|
1.0
|
C10
|
B:7O9501
|
4.5
|
52.0
|
1.0
|
CA
|
B:ALA360
|
4.9
|
39.4
|
1.0
|
C9
|
B:7O9501
|
4.9
|
52.0
|
1.0
|
CZ
|
B:TYR383
|
5.0
|
44.6
|
1.0
|
|
Fluorine binding site 7 out
of 9 in 6x14
Go back to
Fluorine Binding Sites List in 6x14
Fluorine binding site 7 out
of 9 in the Inward-Facing State of the Glutamate Transporter Homologue Gltph in Complex with Tfb-Tboa
Mono view
Stereo pair view
|
A full contact list of Fluorine with other atoms in the F binding
site number 7 of Inward-Facing State of the Glutamate Transporter Homologue Gltph in Complex with Tfb-Tboa within 5.0Å range:
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
C:F501
b:52.0
occ:1.00
|
F2
|
C:7O9501
|
0.0
|
52.0
|
1.0
|
C13
|
C:7O9501
|
1.4
|
52.0
|
1.0
|
F
|
C:7O9501
|
2.2
|
52.0
|
1.0
|
F1
|
C:7O9501
|
2.2
|
52.0
|
1.0
|
C12
|
C:7O9501
|
2.3
|
52.0
|
1.0
|
C14
|
C:7O9501
|
2.8
|
52.0
|
1.0
|
CZ
|
C:PHE50
|
3.1
|
35.6
|
1.0
|
CD1
|
C:ILE16
|
3.3
|
48.0
|
1.0
|
C11
|
C:7O9501
|
3.5
|
52.0
|
1.0
|
CE2
|
C:PHE50
|
3.7
|
35.6
|
1.0
|
CB
|
C:ALA205
|
3.9
|
40.3
|
1.0
|
C15
|
C:7O9501
|
4.1
|
52.0
|
1.0
|
CE1
|
C:PHE50
|
4.2
|
35.6
|
1.0
|
SD
|
C:MET202
|
4.5
|
41.5
|
1.0
|
C10
|
C:7O9501
|
4.6
|
52.0
|
1.0
|
CG1
|
C:ILE16
|
4.7
|
48.0
|
1.0
|
CD1
|
C:LEU54
|
4.7
|
33.2
|
1.0
|
CD2
|
C:LEU387
|
4.7
|
42.9
|
1.0
|
CE
|
C:MET202
|
4.8
|
41.5
|
1.0
|
C9
|
C:7O9501
|
4.9
|
52.0
|
1.0
|
|
Fluorine binding site 8 out
of 9 in 6x14
Go back to
Fluorine Binding Sites List in 6x14
Fluorine binding site 8 out
of 9 in the Inward-Facing State of the Glutamate Transporter Homologue Gltph in Complex with Tfb-Tboa
Mono view
Stereo pair view
|
A full contact list of Fluorine with other atoms in the F binding
site number 8 of Inward-Facing State of the Glutamate Transporter Homologue Gltph in Complex with Tfb-Tboa within 5.0Å range:
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
C:F501
b:52.0
occ:1.00
|
F
|
C:7O9501
|
0.0
|
52.0
|
1.0
|
C13
|
C:7O9501
|
1.4
|
52.0
|
1.0
|
F2
|
C:7O9501
|
2.2
|
52.0
|
1.0
|
F1
|
C:7O9501
|
2.2
|
52.0
|
1.0
|
C12
|
C:7O9501
|
2.4
|
52.0
|
1.0
|
C11
|
C:7O9501
|
2.7
|
52.0
|
1.0
|
CD1
|
C:ILE16
|
3.3
|
48.0
|
1.0
|
CD2
|
C:LEU387
|
3.3
|
42.9
|
1.0
|
C14
|
C:7O9501
|
3.6
|
52.0
|
1.0
|
CG
|
C:LEU387
|
3.9
|
42.9
|
1.0
|
C10
|
C:7O9501
|
4.1
|
52.0
|
1.0
|
CG1
|
C:ILE16
|
4.3
|
48.0
|
1.0
|
CG2
|
C:VAL209
|
4.4
|
39.6
|
1.0
|
C15
|
C:7O9501
|
4.7
|
52.0
|
1.0
|
CZ
|
C:PHE50
|
4.7
|
35.6
|
1.0
|
CE2
|
C:PHE50
|
4.8
|
35.6
|
1.0
|
CB
|
C:VAL209
|
4.8
|
39.6
|
1.0
|
CB
|
C:LEU387
|
4.9
|
42.9
|
1.0
|
C9
|
C:7O9501
|
4.9
|
52.0
|
1.0
|
CD1
|
C:LEU387
|
5.0
|
42.9
|
1.0
|
|
Fluorine binding site 9 out
of 9 in 6x14
Go back to
Fluorine Binding Sites List in 6x14
Fluorine binding site 9 out
of 9 in the Inward-Facing State of the Glutamate Transporter Homologue Gltph in Complex with Tfb-Tboa
Mono view
Stereo pair view
|
A full contact list of Fluorine with other atoms in the F binding
site number 9 of Inward-Facing State of the Glutamate Transporter Homologue Gltph in Complex with Tfb-Tboa within 5.0Å range:
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
C:F501
b:52.0
occ:1.00
|
F1
|
C:7O9501
|
0.0
|
52.0
|
1.0
|
C13
|
C:7O9501
|
1.4
|
52.0
|
1.0
|
F2
|
C:7O9501
|
2.2
|
52.0
|
1.0
|
F
|
C:7O9501
|
2.2
|
52.0
|
1.0
|
C12
|
C:7O9501
|
2.4
|
52.0
|
1.0
|
C14
|
C:7O9501
|
3.0
|
52.0
|
1.0
|
C11
|
C:7O9501
|
3.3
|
52.0
|
1.0
|
CD2
|
C:LEU387
|
3.3
|
42.9
|
1.0
|
CB
|
C:ALA360
|
3.9
|
39.4
|
1.0
|
CD1
|
C:LEU54
|
4.0
|
33.2
|
1.0
|
CG
|
C:LEU387
|
4.1
|
42.9
|
1.0
|
CZ
|
C:PHE50
|
4.1
|
35.6
|
1.0
|
CE2
|
C:PHE50
|
4.2
|
35.6
|
1.0
|
OH
|
C:TYR383
|
4.2
|
44.6
|
1.0
|
C15
|
C:7O9501
|
4.3
|
52.0
|
1.0
|
CD1
|
C:LEU387
|
4.5
|
42.9
|
1.0
|
C10
|
C:7O9501
|
4.5
|
52.0
|
1.0
|
CA
|
C:ALA360
|
4.9
|
39.4
|
1.0
|
C9
|
C:7O9501
|
4.9
|
52.0
|
1.0
|
CZ
|
C:TYR383
|
5.0
|
44.6
|
1.0
|
|
Reference:
X.Wang,
O.Boudker.
Large Domain Movements Through the Lipid Bilayer Mediate Substrate Release and Inhibition of Glutamate Transporters. Elife V. 9 2020.
ISSN: ESSN 2050-084X
PubMed: 33155546
DOI: 10.7554/ELIFE.58417
Page generated: Fri Aug 2 03:55:01 2024
|