Fluorine in PDB 6x1a: Non Peptide Agonist Pf-06882961, Bound to Glucagon-Like Peptide-1 (Glp-1) Receptor

The binding sites of Fluorine atom in the Non Peptide Agonist Pf-06882961, Bound to Glucagon-Like Peptide-1 (Glp-1) Receptor (pdb code 6x1a). This binding sites where shown within 5.0 Angstroms radius around Fluorine atom.
In total only one binding site of Fluorine was determined in the Non Peptide Agonist Pf-06882961, Bound to Glucagon-Like Peptide-1 (Glp-1) Receptor, PDB code: 6x1a:

Fluorine binding site 1 out of 1 in the Non Peptide Agonist Pf-06882961, Bound to Glucagon-Like Peptide-1 (Glp-1) Receptor


Mono view


Stereo pair view

A full contact list of Fluorine with other atoms in the F binding site number 1 of Non Peptide Agonist Pf-06882961, Bound to Glucagon-Like Peptide-1 (Glp-1) Receptor within 5.0Å range: probe atom residue distance (Å) B Occ R:F501 b:25.2 occ:1.00 F01 R:UK4501 0.0 25.2 1.0 C02 R:UK4501 1.4 25.2 1.0 C41 R:UK4501 2.4 25.2 1.0 C03 R:UK4501 2.4 25.2 1.0 C04 R:UK4501 2.8 25.2 1.0 CB R:TRP203 3.3 28.9 1.0 C38 R:UK4501 3.6 25.2 1.0 C36 R:UK4501 3.6 25.2 1.0 CA R:TRP203 3.8 28.9 1.0 CD2 R:LEU217 3.9 36.2 1.0 C32 R:UK4501 4.0 25.2 1.0 N07 R:UK4501 4.0 25.2 1.0 O05 R:UK4501 4.1 25.2 1.0 C37 R:UK4501 4.1 25.2 1.0 CB R:SER206 4.3 36.8 1.0 C06 R:UK4501 4.5 25.2 1.0 CD1 R:LEU217 4.5 36.2 1.0 C31 R:UK4501 4.6 25.2 1.0 CG R:TRP203 4.7 28.9 1.0 CG R:LEU217 4.7 36.2 1.0 O R:TRP203 4.7 28.9 1.0 N R:TRP203 4.8 28.9 1.0 C R:TRP203 4.8 28.9 1.0 C08 R:UK4501 4.9 25.2 1.0 C39 R:UK4501 4.9 25.2 1.0 OG R:SER206 5.0 36.8 1.0

X.Zhang, M.J.Belousoff, P.Zhao, A.J.Kooistra, T.T.Truong, S.Y.Ang, C.R.Underwood, T.Egebjerg, P.Senel, G.D.Stewart, Y.L.Liang, A.Glukhova, H.Venugopal, A.Christopoulos, S.G.B.Furness, L.J.Miller, S.Reedtz-Runge, C.J.Langmead, D.E.Gloriam, R.Danev, P.M.Sexton, D.Wootten. Differential Glp-1R Binding and Activation By Peptide and Non-Peptide Agonists. Mol.Cell V. 80 485 2020.
ISSN: ISSN 1097-2765
PubMed: 33027691
DOI: 10.1016/J.MOLCEL.2020.09.020