Atomistry » Fluorine » PDB 6wqn-6xdm » 6x2h
Atomistry »
  Fluorine »
    PDB 6wqn-6xdm »
      6x2h »

Fluorine in PDB 6x2h: Crystal Structure of PT2863 Bound to HIF2A-B*:Arnt-B* Complex

Protein crystallography data

The structure of Crystal Structure of PT2863 Bound to HIF2A-B*:Arnt-B* Complex, PDB code: 6x2h was solved by X.Du, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å) 29.04 / 2.00
Space group C 1 2 1
Cell size a, b, c (Å), α, β, γ (°) 73.045, 84.443, 41.473, 90, 106.73, 90
R / Rfree (%) 20 / 25.8

Fluorine Binding Sites:

The binding sites of Fluorine atom in the Crystal Structure of PT2863 Bound to HIF2A-B*:Arnt-B* Complex (pdb code 6x2h). This binding sites where shown within 5.0 Angstroms radius around Fluorine atom.
In total 5 binding sites of Fluorine where determined in the Crystal Structure of PT2863 Bound to HIF2A-B*:Arnt-B* Complex, PDB code: 6x2h:
Jump to Fluorine binding site number: 1; 2; 3; 4; 5;

Fluorine binding site 1 out of 5 in 6x2h

Go back to Fluorine Binding Sites List in 6x2h
Fluorine binding site 1 out of 5 in the Crystal Structure of PT2863 Bound to HIF2A-B*:Arnt-B* Complex


Mono view


Stereo pair view

A full contact list of Fluorine with other atoms in the F binding site number 1 of Crystal Structure of PT2863 Bound to HIF2A-B*:Arnt-B* Complex within 5.0Å range:
probe atom residue distance (Å) B Occ
A:F401

b:24.9
occ:1.00
 F2 A:ULD401 0.0 24.9 1.0
C5 A:ULD401 1.3 28.2 1.0
F1 A:ULD401 2.1 28.9 1.0
C9 A:ULD401 2.4 24.7 1.0
C6 A:ULD401 2.4 25.9 1.0
O1 A:ULD401 2.6 29.8 1.0
CD1 A:ILE337 3.5 22.1 1.0
CA A:MET252 3.5 26.3 1.0
C8 A:ULD401 3.5 23.8 1.0
CG A:MET252 3.6 31.7 1.0
C7 A:ULD401 3.6 26.6 1.0
CE1 A:HIS293 3.7 27.1 1.0
ND1 A:HIS293 3.8 28.9 1.0
CB A:HIS248 3.8 17.3 1.0
CB A:MET252 3.8 28.0 1.0
CG A:HIS248 4.1 19.6 1.0
N A:MET252 4.2 25.6 1.0
O A:SER249 4.4 20.4 1.0
C A:MET252 4.5 22.9 1.0
CE A:MET252 4.5 35.1 1.0
ND1 A:HIS248 4.5 16.8 1.0
CG2 A:ILE337 4.6 20.1 1.0
O A:MET252 4.6 23.6 1.0
CG1 A:ILE337 4.6 24.4 1.0
CB A:ILE337 4.6 22.4 1.0
CD2 A:HIS248 4.8 17.4 1.0
C2 A:ULD401 4.8 21.2 1.0
SD A:MET252 4.9 38.1 1.0
C1 A:ULD401 5.0 28.1 1.0

Fluorine binding site 2 out of 5 in 6x2h

Go back to Fluorine Binding Sites List in 6x2h
Fluorine binding site 2 out of 5 in the Crystal Structure of PT2863 Bound to HIF2A-B*:Arnt-B* Complex


Mono view


Stereo pair view

A full contact list of Fluorine with other atoms in the F binding site number 2 of Crystal Structure of PT2863 Bound to HIF2A-B*:Arnt-B* Complex within 5.0Å range:
probe atom residue distance (Å) B Occ
A:F401

b:28.9
occ:1.00
 F1 A:ULD401 0.0 28.9 1.0
C5 A:ULD401 1.3 28.2 1.0
F2 A:ULD401 2.1 24.9 1.0
C6 A:ULD401 2.3 25.9 1.0
C9 A:ULD401 2.4 24.7 1.0
C8 A:ULD401 3.0 23.8 1.0
CG2 A:ILE337 3.0 20.1 1.0
C7 A:ULD401 3.1 26.6 1.0
SG A:CYS339 3.2 22.4 1.0
O1 A:ULD401 3.4 29.8 1.0
CB A:ILE337 3.6 22.4 1.0
CD1 A:ILE337 3.6 22.1 1.0
CG A:HIS248 3.8 19.6 1.0
CB A:HIS248 3.8 17.3 1.0
CD2 A:HIS248 3.8 17.4 1.0
F3 A:ULD401 4.1 32.0 1.0
C2 A:ULD401 4.2 21.2 1.0
CG1 A:ILE337 4.2 24.4 1.0
C1 A:ULD401 4.3 28.1 1.0
ND1 A:HIS248 4.6 16.8 1.0
CD2 A:LEU296 4.6 29.9 1.0
NE2 A:HIS248 4.6 17.7 1.0
O4 A:ULD401 4.7 19.5 1.0
O A:ILE337 4.9 21.2 1.0
CA A:ILE337 4.9 20.8 1.0
O3 A:ULD401 5.0 29.8 1.0
CB A:CYS339 5.0 19.1 1.0

Fluorine binding site 3 out of 5 in 6x2h

Go back to Fluorine Binding Sites List in 6x2h
Fluorine binding site 3 out of 5 in the Crystal Structure of PT2863 Bound to HIF2A-B*:Arnt-B* Complex


Mono view


Stereo pair view

A full contact list of Fluorine with other atoms in the F binding site number 3 of Crystal Structure of PT2863 Bound to HIF2A-B*:Arnt-B* Complex within 5.0Å range:
probe atom residue distance (Å) B Occ
A:F401

b:32.0
occ:1.00
 F3 A:ULD401 0.0 32.0 1.0
C10 A:ULD401 1.3 33.3 1.0
F4 A:ULD401 2.1 41.4 1.0
F5 A:ULD401 2.2 31.1 1.0
S1 A:ULD401 2.4 31.6 1.0
C1 A:ULD401 2.8 28.1 1.0
O3 A:ULD401 2.9 29.8 1.0
C7 A:ULD401 3.2 26.6 1.0
CD2 A:LEU296 3.2 29.9 1.0
C6 A:ULD401 3.4 25.9 1.0
CA A:GLY323 3.4 21.2 1.0
O2 A:ULD401 3.6 32.6 1.0
C4 A:ULD401 3.8 23.5 1.0
N A:GLY323 4.0 20.5 1.0
F1 A:ULD401 4.1 28.9 1.0
CG A:LEU296 4.2 28.8 1.0
SG A:CYS339 4.3 22.4 1.0
CD1 A:LEU296 4.3 28.1 1.0
C8 A:ULD401 4.4 23.8 1.0
O1 A:ULD401 4.4 29.8 1.0
C5 A:ULD401 4.4 28.2 1.0
CG2 A:THR321 4.5 22.6 1.0
C A:GLY323 4.5 24.4 1.0
CG2 A:ILE337 4.6 20.1 1.0
CB A:LEU296 4.6 30.8 1.0
O A:VAL302 4.8 36.0 1.0
C3 A:ULD401 4.8 21.5 1.0
C A:GLN322 4.8 25.0 1.0

Fluorine binding site 4 out of 5 in 6x2h

Go back to Fluorine Binding Sites List in 6x2h
Fluorine binding site 4 out of 5 in the Crystal Structure of PT2863 Bound to HIF2A-B*:Arnt-B* Complex


Mono view


Stereo pair view

A full contact list of Fluorine with other atoms in the F binding site number 4 of Crystal Structure of PT2863 Bound to HIF2A-B*:Arnt-B* Complex within 5.0Å range:
probe atom residue distance (Å) B Occ
A:F401

b:41.4
occ:1.00
 F4 A:ULD401 0.0 41.4 1.0
C10 A:ULD401 1.3 33.3 1.0
F3 A:ULD401 2.1 32.0 1.0
F5 A:ULD401 2.2 31.1 1.0
S1 A:ULD401 2.5 31.6 1.0
O2 A:ULD401 3.0 32.6 1.0
O3 A:ULD401 3.0 29.8 1.0
CG1 A:VAL302 3.1 39.2 1.0
O A:VAL302 3.6 36.0 1.0
CB A:VAL302 3.7 36.1 1.0
C1 A:ULD401 3.9 28.1 1.0
CD2 A:LEU296 3.9 29.9 1.0
CB A:LEU296 4.0 30.8 1.0
C A:VAL302 4.0 36.2 1.0
CD1 A:LEU296 4.0 28.1 1.0
O A:SER292 4.2 33.6 1.0
CA A:GLY323 4.2 21.2 1.0
CG A:LEU296 4.2 28.8 1.0
N A:GLY323 4.2 20.5 1.0
CA A:VAL302 4.4 33.8 1.0
N A:SER304 4.4 30.6 1.0
C A:SER292 4.6 33.4 1.0
C4 A:ULD401 4.7 23.5 1.0
CA A:SER304 4.7 29.4 1.0
CB A:SER292 4.7 32.4 1.0
C7 A:ULD401 4.8 26.6 1.0
N A:VAL303 4.8 31.8 1.0
N A:VAL302 4.8 36.0 1.0
C A:VAL303 4.8 37.0 1.0
CB A:SER304 4.9 24.5 1.0
C6 A:ULD401 5.0 25.9 1.0

Fluorine binding site 5 out of 5 in 6x2h

Go back to Fluorine Binding Sites List in 6x2h
Fluorine binding site 5 out of 5 in the Crystal Structure of PT2863 Bound to HIF2A-B*:Arnt-B* Complex


Mono view


Stereo pair view

A full contact list of Fluorine with other atoms in the F binding site number 5 of Crystal Structure of PT2863 Bound to HIF2A-B*:Arnt-B* Complex within 5.0Å range:
probe atom residue distance (Å) B Occ
A:F401

b:31.1
occ:1.00
 F5 A:ULD401 0.0 31.1 1.0
C10 A:ULD401 1.3 33.3 1.0
F3 A:ULD401 2.2 32.0 1.0
F4 A:ULD401 2.2 41.4 1.0
S1 A:ULD401 2.5 31.6 1.0
O2 A:ULD401 2.8 32.6 1.0
C1 A:ULD401 3.1 28.1 1.0
C4 A:ULD401 3.3 23.5 1.0
CG2 A:THR321 3.4 22.6 1.0
O A:THR321 3.5 30.7 1.0
N A:GLY323 3.6 20.5 1.0
O3 A:ULD401 3.7 29.8 1.0
CB A:SER304 3.8 24.5 1.0
CB A:THR321 3.8 22.4 1.0
N A:SER304 3.9 30.6 1.0
CA A:GLY323 3.9 21.2 1.0
O A:VAL302 3.9 36.0 1.0
C A:THR321 4.0 25.4 1.0
C7 A:ULD401 4.1 26.6 1.0
CA A:SER304 4.2 29.4 1.0
C A:GLN322 4.2 25.0 1.0
C3 A:ULD401 4.5 21.5 1.0
CA A:GLN322 4.6 27.8 1.0
CA A:THR321 4.6 22.2 1.0
N A:GLN322 4.6 27.0 1.0
OG A:SER304 4.7 20.3 1.0
CG1 A:VAL302 4.7 39.2 1.0
C A:VAL302 4.7 36.2 1.0
C A:VAL303 4.8 37.0 1.0
C6 A:ULD401 4.9 25.9 1.0
O A:GLN322 4.9 22.5 1.0

Reference:

X.Du, X.Du. N/A N/A.
Page generated: Sat Jul 10 13:52:53 2021

Last articles

Zn in 7VD8
Zn in 7V1R
Zn in 7V1Q
Zn in 7VPF
Zn in 7T85
Zn in 7T5F
Zn in 7NF9
Zn in 7M4M
Zn in 7M4O
Zn in 7M4N
© Copyright 2008-2020 by atomistry.com
Home   |    Site Map   |    Copyright   |    Contact us   |    Privacy