Atomistry » Fluorine » PDB 6wkd-6x37 » 6x2h
Atomistry »
  Fluorine »
    PDB 6wkd-6x37 »
      6x2h »

Fluorine in PDB 6x2h: Crystal Structure of PT2863 Bound to HIF2A-B*:Arnt-B* Complex

Protein crystallography data

The structure of Crystal Structure of PT2863 Bound to HIF2A-B*:Arnt-B* Complex, PDB code: 6x2h was solved by X.Du, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å) 29.04 / 2.00
Space group C 1 2 1
Cell size a, b, c (Å), α, β, γ (°) 73.045, 84.443, 41.473, 90, 106.73, 90
R / Rfree (%) 20 / 25.8

Fluorine Binding Sites:

The binding sites of Fluorine atom in the Crystal Structure of PT2863 Bound to HIF2A-B*:Arnt-B* Complex (pdb code 6x2h). This binding sites where shown within 5.0 Angstroms radius around Fluorine atom.
In total 5 binding sites of Fluorine where determined in the Crystal Structure of PT2863 Bound to HIF2A-B*:Arnt-B* Complex, PDB code: 6x2h:
Jump to Fluorine binding site number: 1; 2; 3; 4; 5;

Fluorine binding site 1 out of 5 in 6x2h

Go back to Fluorine Binding Sites List in 6x2h
Fluorine binding site 1 out of 5 in the Crystal Structure of PT2863 Bound to HIF2A-B*:Arnt-B* Complex


Mono view


Stereo pair view

A full contact list of Fluorine with other atoms in the F binding site number 1 of Crystal Structure of PT2863 Bound to HIF2A-B*:Arnt-B* Complex within 5.0Å range:
probe atom residue distance (Å) B Occ
A:F401

b:24.9
occ:1.00
 F2 A:ULD401 0.0 24.9 1.0
C5 A:ULD401 1.3 28.2 1.0
F1 A:ULD401 2.1 28.9 1.0
C9 A:ULD401 2.4 24.7 1.0
C6 A:ULD401 2.4 25.9 1.0
O1 A:ULD401 2.6 29.8 1.0
CD1 A:ILE337 3.5 22.1 1.0
CA A:MET252 3.5 26.3 1.0
C8 A:ULD401 3.5 23.8 1.0
CG A:MET252 3.6 31.7 1.0
C7 A:ULD401 3.6 26.6 1.0
CE1 A:HIS293 3.7 27.1 1.0
ND1 A:HIS293 3.8 28.9 1.0
CB A:HIS248 3.8 17.3 1.0
CB A:MET252 3.8 28.0 1.0
CG A:HIS248 4.1 19.6 1.0
N A:MET252 4.2 25.6 1.0
O A:SER249 4.4 20.4 1.0
C A:MET252 4.5 22.9 1.0
CE A:MET252 4.5 35.1 1.0
ND1 A:HIS248 4.5 16.8 1.0
CG2 A:ILE337 4.6 20.1 1.0
O A:MET252 4.6 23.6 1.0
CG1 A:ILE337 4.6 24.4 1.0
CB A:ILE337 4.6 22.4 1.0
CD2 A:HIS248 4.8 17.4 1.0
C2 A:ULD401 4.8 21.2 1.0
SD A:MET252 4.9 38.1 1.0
C1 A:ULD401 5.0 28.1 1.0

Fluorine binding site 2 out of 5 in 6x2h

Go back to Fluorine Binding Sites List in 6x2h
Fluorine binding site 2 out of 5 in the Crystal Structure of PT2863 Bound to HIF2A-B*:Arnt-B* Complex


Mono view


Stereo pair view

A full contact list of Fluorine with other atoms in the F binding site number 2 of Crystal Structure of PT2863 Bound to HIF2A-B*:Arnt-B* Complex within 5.0Å range:
probe atom residue distance (Å) B Occ
A:F401

b:28.9
occ:1.00
 F1 A:ULD401 0.0 28.9 1.0
C5 A:ULD401 1.3 28.2 1.0
F2 A:ULD401 2.1 24.9 1.0
C6 A:ULD401 2.3 25.9 1.0
C9 A:ULD401 2.4 24.7 1.0
C8 A:ULD401 3.0 23.8 1.0
CG2 A:ILE337 3.0 20.1 1.0
C7 A:ULD401 3.1 26.6 1.0
SG A:CYS339 3.2 22.4 1.0
O1 A:ULD401 3.4 29.8 1.0
CB A:ILE337 3.6 22.4 1.0
CD1 A:ILE337 3.6 22.1 1.0
CG A:HIS248 3.8 19.6 1.0
CB A:HIS248 3.8 17.3 1.0
CD2 A:HIS248 3.8 17.4 1.0
F3 A:ULD401 4.1 32.0 1.0
C2 A:ULD401 4.2 21.2 1.0
CG1 A:ILE337 4.2 24.4 1.0
C1 A:ULD401 4.3 28.1 1.0
ND1 A:HIS248 4.6 16.8 1.0
CD2 A:LEU296 4.6 29.9 1.0
NE2 A:HIS248 4.6 17.7 1.0
O4 A:ULD401 4.7 19.5 1.0
O A:ILE337 4.9 21.2 1.0
CA A:ILE337 4.9 20.8 1.0
O3 A:ULD401 5.0 29.8 1.0
CB A:CYS339 5.0 19.1 1.0

Fluorine binding site 3 out of 5 in 6x2h

Go back to Fluorine Binding Sites List in 6x2h
Fluorine binding site 3 out of 5 in the Crystal Structure of PT2863 Bound to HIF2A-B*:Arnt-B* Complex


Mono view


Stereo pair view

A full contact list of Fluorine with other atoms in the F binding site number 3 of Crystal Structure of PT2863 Bound to HIF2A-B*:Arnt-B* Complex within 5.0Å range:
probe atom residue distance (Å) B Occ
A:F401

b:32.0
occ:1.00
 F3 A:ULD401 0.0 32.0 1.0
C10 A:ULD401 1.3 33.3 1.0
F4 A:ULD401 2.1 41.4 1.0
F5 A:ULD401 2.2 31.1 1.0
S1 A:ULD401 2.4 31.6 1.0
C1 A:ULD401 2.8 28.1 1.0
O3 A:ULD401 2.9 29.8 1.0
C7 A:ULD401 3.2 26.6 1.0
CD2 A:LEU296 3.2 29.9 1.0
C6 A:ULD401 3.4 25.9 1.0
CA A:GLY323 3.4 21.2 1.0
O2 A:ULD401 3.6 32.6 1.0
C4 A:ULD401 3.8 23.5 1.0
N A:GLY323 4.0 20.5 1.0
F1 A:ULD401 4.1 28.9 1.0
CG A:LEU296 4.2 28.8 1.0
SG A:CYS339 4.3 22.4 1.0
CD1 A:LEU296 4.3 28.1 1.0
C8 A:ULD401 4.4 23.8 1.0
O1 A:ULD401 4.4 29.8 1.0
C5 A:ULD401 4.4 28.2 1.0
CG2 A:THR321 4.5 22.6 1.0
C A:GLY323 4.5 24.4 1.0
CG2 A:ILE337 4.6 20.1 1.0
CB A:LEU296 4.6 30.8 1.0
O A:VAL302 4.8 36.0 1.0
C3 A:ULD401 4.8 21.5 1.0
C A:GLN322 4.8 25.0 1.0

Fluorine binding site 4 out of 5 in 6x2h

Go back to Fluorine Binding Sites List in 6x2h
Fluorine binding site 4 out of 5 in the Crystal Structure of PT2863 Bound to HIF2A-B*:Arnt-B* Complex


Mono view


Stereo pair view

A full contact list of Fluorine with other atoms in the F binding site number 4 of Crystal Structure of PT2863 Bound to HIF2A-B*:Arnt-B* Complex within 5.0Å range:
probe atom residue distance (Å) B Occ
A:F401

b:41.4
occ:1.00
 F4 A:ULD401 0.0 41.4 1.0
C10 A:ULD401 1.3 33.3 1.0
F3 A:ULD401 2.1 32.0 1.0
F5 A:ULD401 2.2 31.1 1.0
S1 A:ULD401 2.5 31.6 1.0
O2 A:ULD401 3.0 32.6 1.0
O3 A:ULD401 3.0 29.8 1.0
CG1 A:VAL302 3.1 39.2 1.0
O A:VAL302 3.6 36.0 1.0
CB A:VAL302 3.7 36.1 1.0
C1 A:ULD401 3.9 28.1 1.0
CD2 A:LEU296 3.9 29.9 1.0
CB A:LEU296 4.0 30.8 1.0
C A:VAL302 4.0 36.2 1.0
CD1 A:LEU296 4.0 28.1 1.0
O A:SER292 4.2 33.6 1.0
CA A:GLY323 4.2 21.2 1.0
CG A:LEU296 4.2 28.8 1.0
N A:GLY323 4.2 20.5 1.0
CA A:VAL302 4.4 33.8 1.0
N A:SER304 4.4 30.6 1.0
C A:SER292 4.6 33.4 1.0
C4 A:ULD401 4.7 23.5 1.0
CA A:SER304 4.7 29.4 1.0
CB A:SER292 4.7 32.4 1.0
C7 A:ULD401 4.8 26.6 1.0
N A:VAL303 4.8 31.8 1.0
N A:VAL302 4.8 36.0 1.0
C A:VAL303 4.8 37.0 1.0
CB A:SER304 4.9 24.5 1.0
C6 A:ULD401 5.0 25.9 1.0

Fluorine binding site 5 out of 5 in 6x2h

Go back to Fluorine Binding Sites List in 6x2h
Fluorine binding site 5 out of 5 in the Crystal Structure of PT2863 Bound to HIF2A-B*:Arnt-B* Complex


Mono view


Stereo pair view

A full contact list of Fluorine with other atoms in the F binding site number 5 of Crystal Structure of PT2863 Bound to HIF2A-B*:Arnt-B* Complex within 5.0Å range:
probe atom residue distance (Å) B Occ
A:F401

b:31.1
occ:1.00
 F5 A:ULD401 0.0 31.1 1.0
C10 A:ULD401 1.3 33.3 1.0
F3 A:ULD401 2.2 32.0 1.0
F4 A:ULD401 2.2 41.4 1.0
S1 A:ULD401 2.5 31.6 1.0
O2 A:ULD401 2.8 32.6 1.0
C1 A:ULD401 3.1 28.1 1.0
C4 A:ULD401 3.3 23.5 1.0
CG2 A:THR321 3.4 22.6 1.0
O A:THR321 3.5 30.7 1.0
N A:GLY323 3.6 20.5 1.0
O3 A:ULD401 3.7 29.8 1.0
CB A:SER304 3.8 24.5 1.0
CB A:THR321 3.8 22.4 1.0
N A:SER304 3.9 30.6 1.0
CA A:GLY323 3.9 21.2 1.0
O A:VAL302 3.9 36.0 1.0
C A:THR321 4.0 25.4 1.0
C7 A:ULD401 4.1 26.6 1.0
CA A:SER304 4.2 29.4 1.0
C A:GLN322 4.2 25.0 1.0
C3 A:ULD401 4.5 21.5 1.0
CA A:GLN322 4.6 27.8 1.0
CA A:THR321 4.6 22.2 1.0
N A:GLN322 4.6 27.0 1.0
OG A:SER304 4.7 20.3 1.0
CG1 A:VAL302 4.7 39.2 1.0
C A:VAL302 4.7 36.2 1.0
C A:VAL303 4.8 37.0 1.0
C6 A:ULD401 4.9 25.9 1.0
O A:GLN322 4.9 22.5 1.0

Reference:

X.Du, X.Du. N/A N/A.
Page generated: Fri Aug 2 03:55:45 2024

Last articles

Zn in 9JPJ
Zn in 9JP7
Zn in 9JPK
Zn in 9JPL
Zn in 9GN6
Zn in 9GN7
Zn in 9GKU
Zn in 9GKW
Zn in 9GKX
Zn in 9GL0
© Copyright 2008-2020 by atomistry.com
Home   |    Site Map   |    Copyright   |    Contact us   |    Privacy