Fluorine in PDB 6x3u: Human Gabaa Receptor ALPHA1-BETA2-GAMMA2 Subtype in Complex with Gaba Plus Flumazenil

The binding sites of Fluorine atom in the Human Gabaa Receptor ALPHA1-BETA2-GAMMA2 Subtype in Complex with Gaba Plus Flumazenil (pdb code 6x3u). This binding sites where shown within 5.0 Angstroms radius around Fluorine atom.
In total only one binding site of Fluorine was determined in the Human Gabaa Receptor ALPHA1-BETA2-GAMMA2 Subtype in Complex with Gaba Plus Flumazenil, PDB code: 6x3u:

Fluorine binding site 1 out of 1 in the Human Gabaa Receptor ALPHA1-BETA2-GAMMA2 Subtype in Complex with Gaba Plus Flumazenil


Mono view


Stereo pair view

A full contact list of Fluorine with other atoms in the F binding site number 1 of Human Gabaa Receptor ALPHA1-BETA2-GAMMA2 Subtype in Complex with Gaba Plus Flumazenil within 5.0Å range: probe atom residue distance (Å) B Occ D:F402 b:12.5 occ:1.00 F21 D:FYP402 0.0 12.5 1.0 C19 D:FYP402 1.3 12.5 1.0 C20 D:FYP402 2.4 12.5 1.0 C18 D:FYP402 2.4 12.5 1.0 NE2 D:HIS102 2.4 18.7 1.0 CD2 D:HIS102 3.4 18.7 1.0 CE1 D:HIS102 3.4 18.7 1.0 C17 D:FYP402 3.6 12.5 1.0 C12 D:FYP402 3.6 12.5 1.0 CG2 D:VAL203 3.8 7.1 1.0 CB D:TYR210 3.8 5.4 1.0 CG D:TYR210 4.0 5.4 1.0 C13 D:FYP402 4.1 12.5 1.0 CD1 D:TYR210 4.2 5.4 1.0 CG2 D:VAL212 4.3 6.9 1.0 CZ D:PHE100 4.5 18.7 1.0 ND1 D:HIS102 4.5 18.7 1.0 CG D:HIS102 4.5 18.7 1.0 CE1 D:PHE100 4.6 18.7 1.0 CD2 D:TYR210 4.6 5.4 1.0 O D:SER159 4.7 9.6 1.0 C10 D:FYP402 4.8 12.5 1.0 O11 D:FYP402 4.9 12.5 1.0 CE1 D:TYR210 5.0 5.4 1.0

J.J.Kim, A.Gharpure, J.Teng, Y.Zhuang, R.J.Howard, S.Zhu, C.M.Noviello, R.M.Walsh Jr., E.Lindahl, R.E.Hibbs. Shared Structural Mechanisms of General Anaesthetics and Benzodiazepines. Nature V. 585 303 2020.
ISSN: ESSN 1476-4687
PubMed: 32879488
DOI: 10.1038/S41586-020-2654-5