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Atomistry » Fluorine » PDB 6x3d-6xk9 » 6xdm » |
Fluorine in PDB 6xdm: Structure of Human HDAC2 in Complex with An Aryl Ketone InhibitorEnzymatic activity of Structure of Human HDAC2 in Complex with An Aryl Ketone Inhibitor
All present enzymatic activity of Structure of Human HDAC2 in Complex with An Aryl Ketone Inhibitor:
3.5.1.98; Protein crystallography data
The structure of Structure of Human HDAC2 in Complex with An Aryl Ketone Inhibitor, PDB code: 6xdm
was solved by
D.J.Klein,
J.Liu,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Other elements in 6xdm:
The structure of Structure of Human HDAC2 in Complex with An Aryl Ketone Inhibitor also contains other interesting chemical elements:
Fluorine Binding Sites:
The binding sites of Fluorine atom in the Structure of Human HDAC2 in Complex with An Aryl Ketone Inhibitor
(pdb code 6xdm). This binding sites where shown within
5.0 Angstroms radius around Fluorine atom.
In total 3 binding sites of Fluorine where determined in the Structure of Human HDAC2 in Complex with An Aryl Ketone Inhibitor, PDB code: 6xdm: Jump to Fluorine binding site number: 1; 2; 3; Fluorine binding site 1 out of 3 in 6xdmGo back to![]() ![]()
Fluorine binding site 1 out
of 3 in the Structure of Human HDAC2 in Complex with An Aryl Ketone Inhibitor
![]() Mono view ![]() Stereo pair view
Fluorine binding site 2 out of 3 in 6xdmGo back to![]() ![]()
Fluorine binding site 2 out
of 3 in the Structure of Human HDAC2 in Complex with An Aryl Ketone Inhibitor
![]() Mono view ![]() Stereo pair view
Fluorine binding site 3 out of 3 in 6xdmGo back to![]() ![]()
Fluorine binding site 3 out
of 3 in the Structure of Human HDAC2 in Complex with An Aryl Ketone Inhibitor
![]() Mono view ![]() Stereo pair view
Reference:
J.Liu,
J.Kelly,
W.Yu,
D.Clausen,
Y.Yu,
H.Kim,
J.L.Duffy,
C.C.Chung,
R.W.Myers,
S.Carroll,
D.J.Klein,
J.Fells,
M.K.Holloway,
J.Wu,
G.Wu,
B.J.Howell,
R.J.O.Barnard,
J.A.Kozlowski.
Selective Class I Hdac Inhibitors Based on Aryl Ketone Zinc Binding Induce Hiv-1 Protein For Clearance. Acs Med.Chem.Lett. V. 11 1476 2020.
Page generated: Tue Jul 15 17:22:33 2025
ISSN: ISSN 1948-5875 PubMed: 32676157 DOI: 10.1021/ACSMEDCHEMLETT.0C00302 |
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