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Atomistry » Fluorine » PDB 6x3d-6xk9 » 6xec | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Atomistry » Fluorine » PDB 6x3d-6xk9 » 6xec » |
Fluorine in PDB 6xec: Structure of Human HDAC2 in Complex with Ketone Inhibitor (Compound O)Enzymatic activity of Structure of Human HDAC2 in Complex with Ketone Inhibitor (Compound O)
All present enzymatic activity of Structure of Human HDAC2 in Complex with Ketone Inhibitor (Compound O):
3.5.1.98; Protein crystallography data
The structure of Structure of Human HDAC2 in Complex with Ketone Inhibitor (Compound O), PDB code: 6xec
was solved by
D.J.Klein,
D.Clausen,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Other elements in 6xec:
The structure of Structure of Human HDAC2 in Complex with Ketone Inhibitor (Compound O) also contains other interesting chemical elements:
Fluorine Binding Sites:
The binding sites of Fluorine atom in the Structure of Human HDAC2 in Complex with Ketone Inhibitor (Compound O)
(pdb code 6xec). This binding sites where shown within
5.0 Angstroms radius around Fluorine atom.
In total 3 binding sites of Fluorine where determined in the Structure of Human HDAC2 in Complex with Ketone Inhibitor (Compound O), PDB code: 6xec: Jump to Fluorine binding site number: 1; 2; 3; Fluorine binding site 1 out of 3 in 6xecGo back to![]() ![]()
Fluorine binding site 1 out
of 3 in the Structure of Human HDAC2 in Complex with Ketone Inhibitor (Compound O)
![]() Mono view ![]() Stereo pair view
Fluorine binding site 2 out of 3 in 6xecGo back to![]() ![]()
Fluorine binding site 2 out
of 3 in the Structure of Human HDAC2 in Complex with Ketone Inhibitor (Compound O)
![]() Mono view ![]() Stereo pair view
Fluorine binding site 3 out of 3 in 6xecGo back to![]() ![]()
Fluorine binding site 3 out
of 3 in the Structure of Human HDAC2 in Complex with Ketone Inhibitor (Compound O)
![]() Mono view ![]() Stereo pair view
Reference:
D.J.Clausen,
J.Liu,
W.Yu,
J.L.Duffy,
C.C.Chung,
R.W.Myers,
D.J.Klein,
J.Fells,
K.Holloway,
J.Wu,
G.Wu,
B.J.Howell,
R.J.O.Barnard,
J.Kozlowski.
Development of A Selective Hdac Inhibitor Aimed at Reactivating the Hiv Latent Reservoir. Bioorg.Med.Chem.Lett. V. 30 27367 2020.
Page generated: Tue Jul 15 17:23:12 2025
ISSN: ESSN 1464-3405 PubMed: 32738976 DOI: 10.1016/J.BMCL.2020.127367 |
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