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Fluorine in PDB 6yaa: Structure of the (Sr) CA2+-Atpase Bound to the Inhibitor Compound CAD204520 and Tnp-AtpEnzymatic activity of Structure of the (Sr) CA2+-Atpase Bound to the Inhibitor Compound CAD204520 and Tnp-Atp
All present enzymatic activity of Structure of the (Sr) CA2+-Atpase Bound to the Inhibitor Compound CAD204520 and Tnp-Atp:
7.2.2.10; Protein crystallography data
The structure of Structure of the (Sr) CA2+-Atpase Bound to the Inhibitor Compound CAD204520 and Tnp-Atp, PDB code: 6yaa
was solved by
S.Heit,
M.Marchesini,
A.Gherli,
A.Montanaro,
L.Patrizi,
C.Sorrentino,
L.Pagliaro,
C.Rompietti,
S.Kitara,
C.E.Olesen,
J.V.Moller,
M.Savi,
L.Bocchi,
R.Vilella,
F.Rizzi,
M.Baglione,
G.Rastelli,
C.Loiacona,
R.Lastarza,
C.Mecucci,
K.Stegmair,
F.Aversa,
D.Stilli,
A.M.Lund Winther,
P.Sportoletti,
W.Dalby-Brown,
G.Roti,
M.Bublitz,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Other elements in 6yaa:
The structure of Structure of the (Sr) CA2+-Atpase Bound to the Inhibitor Compound CAD204520 and Tnp-Atp also contains other interesting chemical elements:
Fluorine Binding Sites:
The binding sites of Fluorine atom in the Structure of the (Sr) CA2+-Atpase Bound to the Inhibitor Compound CAD204520 and Tnp-Atp
(pdb code 6yaa). This binding sites where shown within
5.0 Angstroms radius around Fluorine atom.
In total 3 binding sites of Fluorine where determined in the Structure of the (Sr) CA2+-Atpase Bound to the Inhibitor Compound CAD204520 and Tnp-Atp, PDB code: 6yaa: Jump to Fluorine binding site number: 1; 2; 3; Fluorine binding site 1 out of 3 in 6yaaGo back to Fluorine Binding Sites List in 6yaa
Fluorine binding site 1 out
of 3 in the Structure of the (Sr) CA2+-Atpase Bound to the Inhibitor Compound CAD204520 and Tnp-Atp
Mono view Stereo pair view
Fluorine binding site 2 out of 3 in 6yaaGo back to Fluorine Binding Sites List in 6yaa
Fluorine binding site 2 out
of 3 in the Structure of the (Sr) CA2+-Atpase Bound to the Inhibitor Compound CAD204520 and Tnp-Atp
Mono view Stereo pair view
Fluorine binding site 3 out of 3 in 6yaaGo back to Fluorine Binding Sites List in 6yaa
Fluorine binding site 3 out
of 3 in the Structure of the (Sr) CA2+-Atpase Bound to the Inhibitor Compound CAD204520 and Tnp-Atp
Mono view Stereo pair view
Reference:
M.Marchesini,
A.Gherli,
A.Montanaro,
L.Patrizi,
C.Sorrentino,
L.Pagliaro,
C.Rompietti,
S.Kitara,
S.Heit,
C.E.Olesen,
J.V.Moller,
M.Savi,
L.Bocchi,
R.Vilella,
F.Rizzi,
M.Baglione,
G.Rastelli,
C.Loiacono,
R.La Starza,
C.Mecucci,
K.Stegmaier,
F.Aversa,
D.Stilli,
A.M.Lund Winther,
P.Sportoletti,
M.Bublitz,
W.Dalby-Brown,
G.Roti.
Blockade of Oncogenic NOTCH1 with the Serca Inhibitor CAD204520 in T Cell Acute Lymphoblastic Leukemia. Cell Chem Biol 2020.
Page generated: Sun Dec 13 13:41:07 2020
ISSN: ESSN 2451-9456 PubMed: 32386594 DOI: 10.1016/J.CHEMBIOL.2020.04.002 |
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