Fluorine in PDB 6yuf: Cohesin Complex with Loader Gripping Dna

The binding sites of Fluorine atom in the Cohesin Complex with Loader Gripping Dna (pdb code 6yuf). This binding sites where shown within 5.0 Angstroms radius around Fluorine atom.
In total 6 binding sites of Fluorine where determined in the Cohesin Complex with Loader Gripping Dna, PDB code: 6yuf:
Jump to Fluorine binding site number: 1; 2; 3; 4; 5; 6;

Fluorine binding site 1 out of 6 in the Cohesin Complex with Loader Gripping Dna


Mono view


Stereo pair view

A full contact list of Fluorine with other atoms in the F binding site number 1 of Cohesin Complex with Loader Gripping Dna within 5.0Å range: probe atom residue distance (Å) B Occ A:F1301 b:99.1 occ:1.00 F1 A:BEF1301 0.0 99.1 1.0 BE A:BEF1301 1.5 99.1 1.0 O1B A:ADP1302 2.3 88.1 1.0 F3 A:BEF1301 2.5 99.1 1.0 F2 A:BEF1301 2.6 99.1 1.0 OG A:SER39 2.6 87.9 1.0 O2B A:ADP1302 2.7 88.1 1.0 PB A:ADP1302 2.8 88.1 1.0 NH1 A:ARG57 3.2 94.6 1.0 CB A:SER39 3.4 87.9 1.0 OE1 A:GLN147 3.5 98.7 1.0 CZ A:ARG57 3.7 94.6 1.0 NE2 A:GLN147 3.7 98.7 1.0 CD A:GLN147 3.9 98.7 1.0 NH2 A:ARG57 3.9 94.6 1.0 O3A A:ADP1302 4.0 88.1 1.0 O2A A:ADP1302 4.2 88.1 1.0 O3B A:ADP1302 4.2 88.1 1.0 PA A:ADP1302 4.2 88.1 1.0 NE A:ARG57 4.5 94.6 1.0 CA A:SER39 4.6 87.9 1.0 N C:GLY1099 4.6 97.1 1.0 N A:SER39 4.7 87.9 1.0 NZ A:LYS38 4.8 89.9 1.0 CA C:SER1098 4.8 98.5 1.0 O1A A:ADP1302 4.8 88.1 1.0 OD2 A:ASP1160 4.9 0.3 1.0 CD A:ARG57 5.0 94.6 1.0

Fluorine binding site 2 out of 6 in the Cohesin Complex with Loader Gripping Dna


Mono view


Stereo pair view

A full contact list of Fluorine with other atoms in the F binding site number 2 of Cohesin Complex with Loader Gripping Dna within 5.0Å range: probe atom residue distance (Å) B Occ A:F1301 b:99.1 occ:1.00 F2 A:BEF1301 0.0 99.1 1.0 BE A:BEF1301 1.6 99.1 1.0 NZ A:LYS38 2.3 89.9 1.0 O2B A:ADP1302 2.3 88.1 1.0 F3 A:BEF1301 2.3 99.1 1.0 PB A:ADP1302 2.3 88.1 1.0 O1B A:ADP1302 2.3 88.1 1.0 F1 A:BEF1301 2.6 99.1 1.0 O3B A:ADP1302 2.8 88.1 1.0 CE A:LYS38 3.2 89.9 1.0 OE1 A:GLN147 3.2 98.7 1.0 CD A:LYS38 3.4 89.9 1.0 OG A:SER39 4.0 87.9 1.0 O3A A:ADP1302 4.1 88.1 1.0 CD A:GLN147 4.1 98.7 1.0 NE2 A:GLN147 4.2 98.7 1.0 CB A:SER39 4.2 87.9 1.0 N A:SER39 4.4 87.9 1.0 C A:LYS38 4.5 89.9 1.0 O A:LYS38 4.6 89.9 1.0 O A:GLY37 4.6 90.3 1.0 CG A:LYS38 4.7 89.9 1.0 CB A:LYS38 4.8 89.9 1.0 PA A:ADP1302 4.9 88.1 1.0 CA A:SER39 4.9 87.9 1.0

Fluorine binding site 3 out of 6 in the Cohesin Complex with Loader Gripping Dna


Mono view


Stereo pair view

A full contact list of Fluorine with other atoms in the F binding site number 3 of Cohesin Complex with Loader Gripping Dna within 5.0Å range: probe atom residue distance (Å) B Occ A:F1301 b:99.1 occ:1.00 F3 A:BEF1301 0.0 99.1 1.0 BE A:BEF1301 1.5 99.1 1.0 F2 A:BEF1301 2.3 99.1 1.0 F1 A:BEF1301 2.5 99.1 1.0 OE1 A:GLN147 2.6 98.7 1.0 CB A:SER39 3.0 87.9 1.0 O1B A:ADP1302 3.1 88.1 1.0 OD1 A:ASP1160 3.3 0.3 1.0 OG A:SER39 3.4 87.9 1.0 OD2 A:ASP1160 3.5 0.3 1.0 CD A:GLN147 3.6 98.7 1.0 CG A:ASP1160 3.8 0.3 1.0 NZ A:LYS38 3.9 89.9 1.0 PB A:ADP1302 4.0 88.1 1.0 O A:LYS38 4.1 89.9 1.0 CA A:SER39 4.1 87.9 1.0 O2B A:ADP1302 4.1 88.1 1.0 CD A:LYS38 4.2 89.9 1.0 NE2 A:GLN147 4.2 98.7 1.0 N A:SER39 4.3 87.9 1.0 C A:LYS38 4.5 89.9 1.0 CG A:GLN147 4.6 98.7 1.0 CD1 A:ILE1191 4.7 98.3 1.0 CE A:LYS38 4.7 89.9 1.0 CG2 A:ILE1191 4.7 98.3 1.0 O3B A:ADP1302 4.7 88.1 1.0 CB A:GLN147 4.8 98.7 1.0 NH1 A:ARG57 4.9 94.6 1.0

Fluorine binding site 4 out of 6 in the Cohesin Complex with Loader Gripping Dna


Mono view


Stereo pair view

A full contact list of Fluorine with other atoms in the F binding site number 4 of Cohesin Complex with Loader Gripping Dna within 5.0Å range: probe atom residue distance (Å) B Occ C:F1201 b:93.3 occ:1.00 F1 C:BEF1201 0.0 93.3 1.0 BE C:BEF1201 1.5 93.3 1.0 O2B C:ADP1202 2.3 92.8 1.0 F3 C:BEF1201 2.5 93.3 1.0 F2 C:BEF1201 2.6 93.3 1.0 OG C:SER39 2.6 92.5 1.0 O1B C:ADP1202 2.7 92.8 1.0 PB C:ADP1202 2.8 92.8 1.0 OE1 C:GLN141 3.2 93.5 1.0 CD C:GLN141 3.8 93.5 1.0 CB C:SER39 3.9 92.5 1.0 N A:GLY1134 3.9 92.7 1.0 O3A C:ADP1202 4.0 92.8 1.0 O1A C:ADP1202 4.2 92.8 1.0 O3B C:ADP1202 4.2 92.8 1.0 PA C:ADP1202 4.2 92.8 1.0 CG C:GLN141 4.2 93.5 1.0 CB A:SER1133 4.3 93.0 1.0 CA A:GLY1134 4.5 92.7 1.0 CB C:GLN141 4.6 93.5 1.0 NE2 C:GLN141 4.6 93.5 1.0 CA A:SER1133 4.8 93.0 1.0 O2A C:ADP1202 4.8 92.8 1.0 C A:SER1133 4.8 93.0 1.0 OG A:SER1133 5.0 93.0 1.0 CA C:SER39 5.0 92.5 1.0

Fluorine binding site 5 out of 6 in the Cohesin Complex with Loader Gripping Dna


Mono view


Stereo pair view

A full contact list of Fluorine with other atoms in the F binding site number 5 of Cohesin Complex with Loader Gripping Dna within 5.0Å range: probe atom residue distance (Å) B Occ C:F1201 b:93.3 occ:1.00 F2 C:BEF1201 0.0 93.3 1.0 BE C:BEF1201 1.6 93.3 1.0 O1B C:ADP1202 2.3 92.8 1.0 F3 C:BEF1201 2.3 93.3 1.0 PB C:ADP1202 2.3 92.8 1.0 O2B C:ADP1202 2.3 92.8 1.0 F1 C:BEF1201 2.6 93.3 1.0 O3B C:ADP1202 2.8 92.8 1.0 O C:ASN34 3.7 92.4 1.0 OE2 C:GLU1126 3.9 0.5 1.0 OE1 C:GLN141 4.0 93.5 1.0 O3A C:ADP1202 4.1 92.8 1.0 OG C:SER39 4.2 92.5 1.0 CD C:LYS38 4.5 87.4 1.0 CD C:GLU1126 4.8 0.5 1.0 C C:ASN34 4.8 92.4 1.0 CD C:GLN141 4.8 93.5 1.0 PA C:ADP1202 4.9 92.8 1.0

Fluorine binding site 6 out of 6 in the Cohesin Complex with Loader Gripping Dna


Mono view


Stereo pair view

A full contact list of Fluorine with other atoms in the F binding site number 6 of Cohesin Complex with Loader Gripping Dna within 5.0Å range: probe atom residue distance (Å) B Occ C:F1201 b:93.3 occ:1.00 F3 C:BEF1201 0.0 93.3 1.0 BE C:BEF1201 1.5 93.3 1.0 OE1 C:GLN141 2.0 93.5 1.0 F2 C:BEF1201 2.3 93.3 1.0 F1 C:BEF1201 2.5 93.3 1.0 CD C:GLN141 3.1 93.5 1.0 O2B C:ADP1202 3.1 92.8 1.0 OG C:SER39 3.4 92.5 1.0 OE2 C:GLU1126 3.6 0.5 1.0 OD2 C:ASP1125 3.7 95.9 1.0 NE2 C:GLN141 3.8 93.5 1.0 CD C:GLU1126 4.0 0.5 1.0 PB C:ADP1202 4.0 92.8 1.0 O1B C:ADP1202 4.1 92.8 1.0 CG C:GLN141 4.2 93.5 1.0 CG C:ASP1125 4.3 95.9 1.0 OD1 C:ASP1125 4.3 95.9 1.0 CG C:GLU1126 4.4 0.5 1.0 CB C:GLN141 4.5 93.5 1.0 OE1 C:GLU1126 4.6 0.5 1.0 O3B C:ADP1202 4.7 92.8 1.0 CB C:SER39 4.8 92.5 1.0

T.L.Higashi, P.Eickhoff, J.S.Sousa, J.Locke, A.Nans, H.R.Flynn, A.P.Snijders, G.Papageorgiou, N.O'reilly, Z.A.Chen, F.J.O'reilly, J.Rappsilber, A.Costa, F.Uhlmann. A Structure-Based Mechanism For Dna Entry Into the Cohesin Ring. Mol.Cell V. 79 917 2020.
ISSN: ISSN 1097-2765
PubMed: 32755595
DOI: 10.1016/J.MOLCEL.2020.07.013