Fluorine in PDB 6yxv: Focal Adhesion Kinase Catalytic Domain in Complex with N-Methyl-N-{3- [(2-Phenylamino-5-Trifluoromethyl-Pyrimidin-4-Ylamino)-Methyl]- Pyridin-2-Yl}-Methanesulfonamide

Enzymatic activity of Focal Adhesion Kinase Catalytic Domain in Complex with N-Methyl-N-{3- [(2-Phenylamino-5-Trifluoromethyl-Pyrimidin-4-Ylamino)-Methyl]- Pyridin-2-Yl}-Methanesulfonamide

All present enzymatic activity of Focal Adhesion Kinase Catalytic Domain in Complex with N-Methyl-N-{3- [(2-Phenylamino-5-Trifluoromethyl-Pyrimidin-4-Ylamino)-Methyl]- Pyridin-2-Yl}-Methanesulfonamide:
2.7.10.2;

Protein crystallography data

The structure of Focal Adhesion Kinase Catalytic Domain in Complex with N-Methyl-N-{3- [(2-Phenylamino-5-Trifluoromethyl-Pyrimidin-4-Ylamino)-Methyl]- Pyridin-2-Yl}-Methanesulfonamide, PDB code: 6yxv was solved by D.Musil, T.Heinrich, M.Amaral, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å) 171.52 / 2.30
Space group C 1 2 1
Cell size a, b, c (Å), α, β, γ (°) 118.05, 77.127, 174.934, 90, 101.34, 90
R / Rfree (%) 20.2 / 23.2

Fluorine Binding Sites:

Pages:

>>> Page 1 <<< Page 2, Binding sites: 11 - 12;

Binding sites:

The binding sites of Fluorine atom in the Focal Adhesion Kinase Catalytic Domain in Complex with N-Methyl-N-{3- [(2-Phenylamino-5-Trifluoromethyl-Pyrimidin-4-Ylamino)-Methyl]- Pyridin-2-Yl}-Methanesulfonamide (pdb code 6yxv). This binding sites where shown within 5.0 Angstroms radius around Fluorine atom.
In total 12 binding sites of Fluorine where determined in the Focal Adhesion Kinase Catalytic Domain in Complex with N-Methyl-N-{3- [(2-Phenylamino-5-Trifluoromethyl-Pyrimidin-4-Ylamino)-Methyl]- Pyridin-2-Yl}-Methanesulfonamide, PDB code: 6yxv:
Jump to Fluorine binding site number: 1; 2; 3; 4; 5; 6; 7; 8; 9; 10;

Fluorine binding site 1 out of 12 in 6yxv

Go back to Fluorine Binding Sites List in 6yxv
Fluorine binding site 1 out of 12 in the Focal Adhesion Kinase Catalytic Domain in Complex with N-Methyl-N-{3- [(2-Phenylamino-5-Trifluoromethyl-Pyrimidin-4-Ylamino)-Methyl]- Pyridin-2-Yl}-Methanesulfonamide


Mono view


Stereo pair view

A full contact list of Fluorine with other atoms in the F binding site number 1 of Focal Adhesion Kinase Catalytic Domain in Complex with N-Methyl-N-{3- [(2-Phenylamino-5-Trifluoromethyl-Pyrimidin-4-Ylamino)-Methyl]- Pyridin-2-Yl}-Methanesulfonamide within 5.0Å range:
probe atom residue distance (Å) B Occ
A:F701

b:47.1
occ:1.00
 F16 A:Q2H701 0.0 47.1 1.0
C15 A:Q2H701 1.4 46.2 1.0
F18 A:Q2H701 2.1 46.6 1.0
F17 A:Q2H701 2.2 46.0 1.0
C12 A:Q2H701 2.4 44.4 1.0
C11 A:Q2H701 2.7 43.3 1.0
CB A:MET499 3.5 51.2 1.0
CG2 A:VAL484 3.6 47.8 1.0
O A:GLU500 3.6 49.7 1.0
CB A:VAL484 3.7 47.5 1.0
C13 A:Q2H701 3.8 43.5 1.0
CG1 A:VAL484 3.8 47.7 1.0
CG A:MET499 4.0 52.3 1.0
N10 A:Q2H701 4.0 42.6 1.0
CB A:ALA452 4.3 46.4 1.0
N8 A:Q2H701 4.4 43.8 1.0
CE A:MET499 4.4 50.6 1.0
CD1 A:LEU553 4.5 38.9 1.0
CB A:ASP564 4.5 48.0 1.0
N A:ASP564 4.6 47.6 1.0
N A:GLU500 4.7 49.1 1.0
C A:GLU500 4.8 48.9 1.0
CA A:MET499 4.8 50.7 1.0
N14 A:Q2H701 4.8 43.0 1.0
C9 A:Q2H701 4.9 42.1 1.0
C A:MET499 4.9 50.1 1.0

Fluorine binding site 2 out of 12 in 6yxv

Go back to Fluorine Binding Sites List in 6yxv
Fluorine binding site 2 out of 12 in the Focal Adhesion Kinase Catalytic Domain in Complex with N-Methyl-N-{3- [(2-Phenylamino-5-Trifluoromethyl-Pyrimidin-4-Ylamino)-Methyl]- Pyridin-2-Yl}-Methanesulfonamide


Mono view


Stereo pair view

A full contact list of Fluorine with other atoms in the F binding site number 2 of Focal Adhesion Kinase Catalytic Domain in Complex with N-Methyl-N-{3- [(2-Phenylamino-5-Trifluoromethyl-Pyrimidin-4-Ylamino)-Methyl]- Pyridin-2-Yl}-Methanesulfonamide within 5.0Å range:
probe atom residue distance (Å) B Occ
A:F701

b:46.0
occ:1.00
 F17 A:Q2H701 0.0 46.0 1.0
C15 A:Q2H701 1.4 46.2 1.0
F18 A:Q2H701 2.2 46.6 1.0
F16 A:Q2H701 2.2 47.1 1.0
C12 A:Q2H701 2.4 44.4 1.0
C13 A:Q2H701 3.1 43.5 1.0
N8 A:Q2H701 3.2 43.8 1.0
C11 A:Q2H701 3.4 43.3 1.0
CB A:ALA452 3.7 46.4 1.0
CD1 A:LEU567 3.7 61.9 1.0
CB A:MET499 3.9 51.2 1.0
CG A:MET499 4.0 52.3 1.0
CB A:ASP564 4.2 48.0 1.0
N14 A:Q2H701 4.4 43.0 1.0
CG1 A:VAL436 4.5 57.0 1.0
N10 A:Q2H701 4.6 42.6 1.0
C7 A:Q2H701 4.7 44.5 1.0
O30 A:Q2H701 4.7 46.8 1.0
CG A:LYS454 4.8 62.4 1.0
C9 A:Q2H701 4.9 42.1 1.0
O A:GLU500 5.0 49.7 1.0

Fluorine binding site 3 out of 12 in 6yxv

Go back to Fluorine Binding Sites List in 6yxv
Fluorine binding site 3 out of 12 in the Focal Adhesion Kinase Catalytic Domain in Complex with N-Methyl-N-{3- [(2-Phenylamino-5-Trifluoromethyl-Pyrimidin-4-Ylamino)-Methyl]- Pyridin-2-Yl}-Methanesulfonamide


Mono view


Stereo pair view

A full contact list of Fluorine with other atoms in the F binding site number 3 of Focal Adhesion Kinase Catalytic Domain in Complex with N-Methyl-N-{3- [(2-Phenylamino-5-Trifluoromethyl-Pyrimidin-4-Ylamino)-Methyl]- Pyridin-2-Yl}-Methanesulfonamide within 5.0Å range:
probe atom residue distance (Å) B Occ
A:F701

b:46.6
occ:1.00
 F18 A:Q2H701 0.0 46.6 1.0
C15 A:Q2H701 1.4 46.2 1.0
F16 A:Q2H701 2.1 47.1 1.0
F17 A:Q2H701 2.2 46.0 1.0
C12 A:Q2H701 2.4 44.4 1.0
N8 A:Q2H701 3.1 43.8 1.0
C13 A:Q2H701 3.1 43.5 1.0
N A:ASP564 3.3 47.6 1.0
O30 A:Q2H701 3.3 46.8 1.0
CB A:ASP564 3.3 48.0 1.0
C11 A:Q2H701 3.5 43.3 1.0
CD1 A:LEU553 3.8 38.9 1.0
CA A:ASP564 3.9 48.5 1.0
CD1 A:LEU567 4.0 61.9 1.0
CG2 A:VAL484 4.1 47.8 1.0
C A:GLY563 4.3 47.5 1.0
C7 A:Q2H701 4.3 44.5 1.0
S28 A:Q2H701 4.3 46.9 1.0
CA A:GLY563 4.3 46.5 1.0
N14 A:Q2H701 4.4 43.0 1.0
O29 A:Q2H701 4.4 47.3 1.0
CG1 A:VAL484 4.5 47.7 1.0
CG A:ASP564 4.6 48.6 1.0
N10 A:Q2H701 4.7 42.6 1.0
CB A:VAL484 4.7 47.5 1.0
C1 A:Q2H701 4.9 44.7 1.0
C9 A:Q2H701 5.0 42.1 1.0

Fluorine binding site 4 out of 12 in 6yxv

Go back to Fluorine Binding Sites List in 6yxv
Fluorine binding site 4 out of 12 in the Focal Adhesion Kinase Catalytic Domain in Complex with N-Methyl-N-{3- [(2-Phenylamino-5-Trifluoromethyl-Pyrimidin-4-Ylamino)-Methyl]- Pyridin-2-Yl}-Methanesulfonamide


Mono view


Stereo pair view

A full contact list of Fluorine with other atoms in the F binding site number 4 of Focal Adhesion Kinase Catalytic Domain in Complex with N-Methyl-N-{3- [(2-Phenylamino-5-Trifluoromethyl-Pyrimidin-4-Ylamino)-Methyl]- Pyridin-2-Yl}-Methanesulfonamide within 5.0Å range:
probe atom residue distance (Å) B Occ
B:F701

b:45.2
occ:1.00
 F16 B:Q2H701 0.0 45.2 1.0
C15 B:Q2H701 1.4 43.8 1.0
F18 B:Q2H701 2.1 43.5 1.0
F17 B:Q2H701 2.2 44.7 1.0
C12 B:Q2H701 2.4 41.3 1.0
C11 B:Q2H701 2.7 40.0 1.0
CB B:MET499 3.2 42.2 1.0
O B:GLU500 3.4 36.5 1.0
C13 B:Q2H701 3.7 40.4 1.0
CG B:MET499 3.7 44.8 1.0
CB B:ALA452 3.8 37.0 1.0
CG2 B:VAL484 4.0 40.4 1.0
N10 B:Q2H701 4.0 39.3 1.0
CB B:VAL484 4.1 40.6 1.0
CG1 B:VAL484 4.2 41.5 1.0
N8 B:Q2H701 4.3 40.8 1.0
CA B:MET499 4.5 41.2 1.0
C B:GLU500 4.6 37.1 1.0
CE B:MET499 4.6 43.3 1.0
CB B:ASP564 4.6 46.4 1.0
C B:MET499 4.7 40.4 1.0
N B:GLU500 4.7 40.0 1.0
N14 B:Q2H701 4.8 39.6 1.0
C9 B:Q2H701 4.8 39.2 1.0
CD1 B:LEU553 4.9 36.2 1.0

Fluorine binding site 5 out of 12 in 6yxv

Go back to Fluorine Binding Sites List in 6yxv
Fluorine binding site 5 out of 12 in the Focal Adhesion Kinase Catalytic Domain in Complex with N-Methyl-N-{3- [(2-Phenylamino-5-Trifluoromethyl-Pyrimidin-4-Ylamino)-Methyl]- Pyridin-2-Yl}-Methanesulfonamide


Mono view


Stereo pair view

A full contact list of Fluorine with other atoms in the F binding site number 5 of Focal Adhesion Kinase Catalytic Domain in Complex with N-Methyl-N-{3- [(2-Phenylamino-5-Trifluoromethyl-Pyrimidin-4-Ylamino)-Methyl]- Pyridin-2-Yl}-Methanesulfonamide within 5.0Å range:
probe atom residue distance (Å) B Occ
B:F701

b:44.7
occ:1.00
 F17 B:Q2H701 0.0 44.7 1.0
C15 B:Q2H701 1.4 43.8 1.0
F16 B:Q2H701 2.2 45.2 1.0
F18 B:Q2H701 2.2 43.5 1.0
C12 B:Q2H701 2.4 41.3 1.0
N8 B:Q2H701 2.9 40.8 1.0
C13 B:Q2H701 3.0 40.4 1.0
CD1 B:LEU567 3.3 58.4 1.0
C11 B:Q2H701 3.6 40.0 1.0
O30 B:Q2H701 3.9 46.1 1.0
CB B:ASP564 3.9 46.4 1.0
CB B:ALA452 4.1 37.0 1.0
C7 B:Q2H701 4.3 42.3 1.0
N14 B:Q2H701 4.3 39.6 1.0
CG B:MET499 4.4 44.8 1.0
CB B:MET499 4.4 42.2 1.0
CG1 B:VAL436 4.6 48.9 1.0
CG B:LEU567 4.7 57.9 1.0
N10 B:Q2H701 4.7 39.3 1.0
CG B:ASP564 4.7 49.4 1.0
C1 B:Q2H701 4.8 44.2 1.0
N B:ASP564 4.9 44.5 1.0
CG B:LYS454 4.9 54.1 1.0
C9 B:Q2H701 4.9 39.2 1.0

Fluorine binding site 6 out of 12 in 6yxv

Go back to Fluorine Binding Sites List in 6yxv
Fluorine binding site 6 out of 12 in the Focal Adhesion Kinase Catalytic Domain in Complex with N-Methyl-N-{3- [(2-Phenylamino-5-Trifluoromethyl-Pyrimidin-4-Ylamino)-Methyl]- Pyridin-2-Yl}-Methanesulfonamide


Mono view


Stereo pair view

A full contact list of Fluorine with other atoms in the F binding site number 6 of Focal Adhesion Kinase Catalytic Domain in Complex with N-Methyl-N-{3- [(2-Phenylamino-5-Trifluoromethyl-Pyrimidin-4-Ylamino)-Methyl]- Pyridin-2-Yl}-Methanesulfonamide within 5.0Å range:
probe atom residue distance (Å) B Occ
B:F701

b:43.5
occ:1.00
 F18 B:Q2H701 0.0 43.5 1.0
C15 B:Q2H701 1.3 43.8 1.0
F16 B:Q2H701 2.1 45.2 1.0
F17 B:Q2H701 2.2 44.7 1.0
C12 B:Q2H701 2.4 41.3 1.0
O30 B:Q2H701 3.2 46.1 1.0
C11 B:Q2H701 3.3 40.0 1.0
C13 B:Q2H701 3.3 40.4 1.0
N B:ASP564 3.3 44.5 1.0
N8 B:Q2H701 3.5 40.8 1.0
CD1 B:LEU553 3.5 36.2 1.0
CB B:ASP564 3.5 46.4 1.0
CG2 B:VAL484 3.7 40.4 1.0
CG1 B:VAL484 3.9 41.5 1.0
CA B:ASP564 4.0 44.7 1.0
CB B:VAL484 4.2 40.6 1.0
CA B:GLY563 4.2 42.9 1.0
C B:GLY563 4.2 44.1 1.0
S28 B:Q2H701 4.3 46.3 1.0
N10 B:Q2H701 4.5 39.3 1.0
N14 B:Q2H701 4.5 39.6 1.0
O29 B:Q2H701 4.5 45.9 1.0
CD1 B:LEU567 4.5 58.4 1.0
CG B:ASP564 4.8 49.4 1.0
C7 B:Q2H701 4.8 42.3 1.0
C9 B:Q2H701 4.9 39.2 1.0
CG B:LEU553 4.9 36.3 1.0

Fluorine binding site 7 out of 12 in 6yxv

Go back to Fluorine Binding Sites List in 6yxv
Fluorine binding site 7 out of 12 in the Focal Adhesion Kinase Catalytic Domain in Complex with N-Methyl-N-{3- [(2-Phenylamino-5-Trifluoromethyl-Pyrimidin-4-Ylamino)-Methyl]- Pyridin-2-Yl}-Methanesulfonamide


Mono view


Stereo pair view

A full contact list of Fluorine with other atoms in the F binding site number 7 of Focal Adhesion Kinase Catalytic Domain in Complex with N-Methyl-N-{3- [(2-Phenylamino-5-Trifluoromethyl-Pyrimidin-4-Ylamino)-Methyl]- Pyridin-2-Yl}-Methanesulfonamide within 5.0Å range:
probe atom residue distance (Å) B Occ
C:F701

b:41.6
occ:1.00
 F16 C:Q2H701 0.0 41.6 1.0
C15 C:Q2H701 1.4 42.0 1.0
F18 C:Q2H701 2.2 42.6 1.0
F17 C:Q2H701 2.2 43.4 1.0
C12 C:Q2H701 2.4 40.4 1.0
C11 C:Q2H701 2.7 39.3 1.0
O C:GLU500 3.3 43.7 1.0
CB C:MET499 3.4 44.9 1.0
C13 C:Q2H701 3.8 39.8 1.0
CG2 C:VAL484 3.9 47.2 1.0
CB C:VAL484 3.9 46.7 1.0
CG1 C:VAL484 3.9 46.9 1.0
CG C:MET499 4.0 47.0 1.0
CB C:ALA452 4.0 42.7 1.0
N10 C:Q2H701 4.1 38.6 1.0
CE C:MET499 4.3 42.6 1.0
N8 C:Q2H701 4.3 40.7 1.0
C C:GLU500 4.5 43.2 1.0
N C:GLU500 4.5 44.8 1.0
CD1 C:LEU553 4.6 34.6 1.0
CA C:MET499 4.6 44.7 1.0
C C:MET499 4.7 45.0 1.0
CB C:ASP564 4.7 45.3 1.0
N14 C:Q2H701 4.8 38.7 1.0
C9 C:Q2H701 4.9 37.9 1.0
N C:ASP564 5.0 43.0 1.0

Fluorine binding site 8 out of 12 in 6yxv

Go back to Fluorine Binding Sites List in 6yxv
Fluorine binding site 8 out of 12 in the Focal Adhesion Kinase Catalytic Domain in Complex with N-Methyl-N-{3- [(2-Phenylamino-5-Trifluoromethyl-Pyrimidin-4-Ylamino)-Methyl]- Pyridin-2-Yl}-Methanesulfonamide


Mono view


Stereo pair view

A full contact list of Fluorine with other atoms in the F binding site number 8 of Focal Adhesion Kinase Catalytic Domain in Complex with N-Methyl-N-{3- [(2-Phenylamino-5-Trifluoromethyl-Pyrimidin-4-Ylamino)-Methyl]- Pyridin-2-Yl}-Methanesulfonamide within 5.0Å range:
probe atom residue distance (Å) B Occ
C:F701

b:43.4
occ:1.00
 F17 C:Q2H701 0.0 43.4 1.0
C15 C:Q2H701 1.3 42.0 1.0
F18 C:Q2H701 2.1 42.6 1.0
F16 C:Q2H701 2.2 41.6 1.0
C12 C:Q2H701 2.4 40.4 1.0
N8 C:Q2H701 2.9 40.7 1.0
C13 C:Q2H701 3.0 39.8 1.0
CD1 C:LEU567 3.4 54.5 1.0
C11 C:Q2H701 3.6 39.3 1.0
CB C:ASP564 4.0 45.3 1.0
O30 C:Q2H701 4.2 45.6 1.0
CB C:ALA452 4.2 42.7 1.0
N14 C:Q2H701 4.3 38.7 1.0
C7 C:Q2H701 4.3 41.7 1.0
CB C:MET499 4.3 44.9 1.0
CG C:MET499 4.4 47.0 1.0
CG1 C:VAL436 4.6 43.3 1.0
N10 C:Q2H701 4.7 38.6 1.0
CG C:ASP564 4.8 49.2 1.0
CG C:LEU567 4.8 54.2 1.0
C1 C:Q2H701 4.8 43.0 1.0
N C:ASP564 4.9 43.0 1.0
CG C:LYS454 4.9 48.7 1.0
C9 C:Q2H701 4.9 37.9 1.0

Fluorine binding site 9 out of 12 in 6yxv

Go back to Fluorine Binding Sites List in 6yxv
Fluorine binding site 9 out of 12 in the Focal Adhesion Kinase Catalytic Domain in Complex with N-Methyl-N-{3- [(2-Phenylamino-5-Trifluoromethyl-Pyrimidin-4-Ylamino)-Methyl]- Pyridin-2-Yl}-Methanesulfonamide


Mono view


Stereo pair view

A full contact list of Fluorine with other atoms in the F binding site number 9 of Focal Adhesion Kinase Catalytic Domain in Complex with N-Methyl-N-{3- [(2-Phenylamino-5-Trifluoromethyl-Pyrimidin-4-Ylamino)-Methyl]- Pyridin-2-Yl}-Methanesulfonamide within 5.0Å range:
probe atom residue distance (Å) B Occ
C:F701

b:42.6
occ:1.00
 F18 C:Q2H701 0.0 42.6 1.0
C15 C:Q2H701 1.3 42.0 1.0
F17 C:Q2H701 2.1 43.4 1.0
F16 C:Q2H701 2.2 41.6 1.0
C12 C:Q2H701 2.4 40.4 1.0
C13 C:Q2H701 3.2 39.8 1.0
N8 C:Q2H701 3.3 40.7 1.0
C11 C:Q2H701 3.3 39.3 1.0
N C:ASP564 3.3 43.0 1.0
CD1 C:LEU553 3.4 34.6 1.0
O30 C:Q2H701 3.4 45.6 1.0
CB C:ASP564 3.6 45.3 1.0
CG2 C:VAL484 3.9 47.2 1.0
CG1 C:VAL484 4.0 46.9 1.0
CA C:ASP564 4.0 43.5 1.0
CA C:GLY563 4.2 41.5 1.0
C C:GLY563 4.2 43.0 1.0
CB C:VAL484 4.3 46.7 1.0
S28 C:Q2H701 4.4 45.4 1.0
CD1 C:LEU567 4.4 54.5 1.0
N14 C:Q2H701 4.4 38.7 1.0
O29 C:Q2H701 4.4 44.7 1.0
N10 C:Q2H701 4.5 38.6 1.0
C7 C:Q2H701 4.5 41.7 1.0
CG C:LEU553 4.7 34.8 1.0
CG C:ASP564 4.8 49.2 1.0
C9 C:Q2H701 4.9 37.9 1.0

Fluorine binding site 10 out of 12 in 6yxv

Go back to Fluorine Binding Sites List in 6yxv
Fluorine binding site 10 out of 12 in the Focal Adhesion Kinase Catalytic Domain in Complex with N-Methyl-N-{3- [(2-Phenylamino-5-Trifluoromethyl-Pyrimidin-4-Ylamino)-Methyl]- Pyridin-2-Yl}-Methanesulfonamide


Mono view


Stereo pair view

A full contact list of Fluorine with other atoms in the F binding site number 10 of Focal Adhesion Kinase Catalytic Domain in Complex with N-Methyl-N-{3- [(2-Phenylamino-5-Trifluoromethyl-Pyrimidin-4-Ylamino)-Methyl]- Pyridin-2-Yl}-Methanesulfonamide within 5.0Å range:
probe atom residue distance (Å) B Occ
D:F701

b:55.2
occ:1.00
 F16 D:Q2H701 0.0 55.2 1.0
C15 D:Q2H701 1.4 55.3 1.0
F17 D:Q2H701 2.1 56.2 1.0
F18 D:Q2H701 2.1 55.6 1.0
C12 D:Q2H701 2.4 53.8 1.0
C11 D:Q2H701 2.8 52.4 1.0
O D:GLU500 3.3 48.5 1.0
CB D:MET499 3.4 48.7 1.0
C13 D:Q2H701 3.8 54.4 1.0
CG2 D:VAL484 4.0 47.0 1.0
CB D:ALA452 4.0 55.0 1.0
CB D:VAL484 4.0 46.7 1.0
N10 D:Q2H701 4.1 52.3 1.0
CG1 D:VAL484 4.1 47.1 1.0
CG D:MET499 4.1 51.6 1.0
CE D:MET499 4.3 43.2 1.0
N8 D:Q2H701 4.4 56.5 1.0
C D:GLU500 4.4 48.4 1.0
C D:MET499 4.7 47.1 1.0
N D:GLU500 4.7 46.4 1.0
CA D:MET499 4.7 47.9 1.0
CB D:ASP564 4.7 54.5 1.0
CD1 D:LEU553 4.7 47.0 1.0
N14 D:Q2H701 4.8 53.5 1.0
C9 D:Q2H701 4.9 53.0 1.0
N D:ASP564 5.0 51.8 1.0

Reference:

B.T.Berger, M.Amaral, D.B.Kokh, A.Nunes-Alves, D.Musil, T.Heinrich, M.Schroder, R.Neil, J.Wang, I.Navratilova, J.Bomke, J.M.Elkins, S.Muller, M.Frech, R.C.Wade, S.Knapp. Structure-Kinetic Relationship Reveals the Mechanism of Selectivity of Fak Inhibitors Over PYK2. Cell Chem Biol 2021.
ISSN: ESSN 2451-9456
PubMed: 33497606
DOI: 10.1016/J.CHEMBIOL.2021.01.003
Page generated: Wed Mar 3 13:30:13 2021

Last articles

Zn in 8WB0
Zn in 8WAX
Zn in 8WAU
Zn in 8WAZ
Zn in 8WAY
Zn in 8WAV
Zn in 8WAW
Zn in 8WAT
Zn in 8W7M
Zn in 8WD3
© Copyright 2008-2020 by atomistry.com
Home   |    Site Map   |    Copyright   |    Contact us   |    Privacy