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Fluorine in PDB 7auz: LTA4 Hydrolase in Complex with Compound LYS006Enzymatic activity of LTA4 Hydrolase in Complex with Compound LYS006
All present enzymatic activity of LTA4 Hydrolase in Complex with Compound LYS006:
3.3.2.6; Protein crystallography data
The structure of LTA4 Hydrolase in Complex with Compound LYS006, PDB code: 7auz
was solved by
H.Srinivas,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Other elements in 7auz:
The structure of LTA4 Hydrolase in Complex with Compound LYS006 also contains other interesting chemical elements:
Fluorine Binding Sites:
The binding sites of Fluorine atom in the LTA4 Hydrolase in Complex with Compound LYS006
(pdb code 7auz). This binding sites where shown within
5.0 Angstroms radius around Fluorine atom.
In total only one binding site of Fluorine was determined in the LTA4 Hydrolase in Complex with Compound LYS006, PDB code: 7auz: Fluorine binding site 1 out of 1 in 7auzGo back to![]() ![]()
Fluorine binding site 1 out
of 1 in the LTA4 Hydrolase in Complex with Compound LYS006
![]() Mono view ![]() Stereo pair view
Reference:
C.Markert,
G.Thoma,
H.Srinivas,
B.Bollbuck,
R.M.Luond,
W.Miltz,
R.Wal̈Chli,
R.Wolf,
J.Hinrichs,
C.Bergsdorf,
K.Azzaoui,
C.A.Penno,
K.Klein,
N.Wack,
P.Jag̈Er,
F.Hasler,
C.Beerli,
P.Loetscher,
J.Dawson,
G.Wieczorek,
S.Numao,
A.Littlewood-Evans,
T.A.Rohn.
Discovery of LYS006, A Potent and Highly Selective Inhibitor of Leukotriene A4 Hydrolase. J.Med.Chem. 2021.
Page generated: Wed Mar 3 13:32:45 2021
ISSN: ISSN 0022-2623 |
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