Atomistry » Fluorine » PDB 7adv-7aym » 7axs
Atomistry »
  Fluorine »
    PDB 7adv-7aym »
      7axs »

Fluorine in PDB 7axs: Structural Characterisation of WDR5:Cs-VIP8 Interaction in Cis State 1

Protein crystallography data

The structure of Structural Characterisation of WDR5:Cs-VIP8 Interaction in Cis State 1, PDB code: 7axs was solved by L.Werel, L.-O.Essen, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å) 44.47 / 1.88
Space group P 21 21 21
Cell size a, b, c (Å), α, β, γ (°) 47.022, 47.163, 133.46, 90, 90, 90
R / Rfree (%) 20 / 23.5

Fluorine Binding Sites:

The binding sites of Fluorine atom in the Structural Characterisation of WDR5:Cs-VIP8 Interaction in Cis State 1 (pdb code 7axs). This binding sites where shown within 5.0 Angstroms radius around Fluorine atom.
In total 4 binding sites of Fluorine where determined in the Structural Characterisation of WDR5:Cs-VIP8 Interaction in Cis State 1, PDB code: 7axs:
Jump to Fluorine binding site number: 1; 2; 3; 4;

Fluorine binding site 1 out of 4 in 7axs

Go back to Fluorine Binding Sites List in 7axs
Fluorine binding site 1 out of 4 in the Structural Characterisation of WDR5:Cs-VIP8 Interaction in Cis State 1


Mono view


Stereo pair view

A full contact list of Fluorine with other atoms in the F binding site number 1 of Structural Characterisation of WDR5:Cs-VIP8 Interaction in Cis State 1 within 5.0Å range:
probe atom residue distance (Å) B Occ
B:F7

b:39.7
occ:1.00
FA2 B:S7Z7 0.0 39.7 1.0
CA2 B:S7Z7 1.4 38.7 1.0
CA1 B:S7Z7 2.4 39.7 1.0
CA3 B:S7Z7 2.4 38.0 1.0
NA1 B:S7Z7 2.9 41.1 1.0
CA6 B:S7Z7 3.6 39.0 1.0
CA4 B:S7Z7 3.7 35.9 1.0
FB2 B:S7Z7 3.7 41.4 1.0
NB1 B:S7Z7 3.8 40.2 1.0
CA5 B:S7Z7 4.1 37.5 1.0
CB2 B:S7Z7 4.5 40.8 1.0
CB1 B:S7Z7 4.6 41.2 1.0
FA6 B:S7Z7 4.7 40.9 1.0
O B:HOH104 4.9 28.5 1.0
CA B:S7Z7 4.9 31.9 1.0

Fluorine binding site 2 out of 4 in 7axs

Go back to Fluorine Binding Sites List in 7axs
Fluorine binding site 2 out of 4 in the Structural Characterisation of WDR5:Cs-VIP8 Interaction in Cis State 1


Mono view


Stereo pair view

A full contact list of Fluorine with other atoms in the F binding site number 2 of Structural Characterisation of WDR5:Cs-VIP8 Interaction in Cis State 1 within 5.0Å range:
probe atom residue distance (Å) B Occ
B:F7

b:40.9
occ:1.00
FA6 B:S7Z7 0.0 40.9 1.0
CA6 B:S7Z7 1.4 39.0 1.0
CA1 B:S7Z7 2.3 39.7 1.0
CA5 B:S7Z7 2.4 37.5 1.0
NA1 B:S7Z7 2.7 41.1 1.0
FB6 B:S7Z7 3.2 41.4 1.0
NB1 B:S7Z7 3.2 40.2 1.0
CB6 B:S7Z7 3.2 41.5 1.0
CB1 B:S7Z7 3.2 41.2 1.0
CE1 B:DPN5 3.3 26.5 1.0
CD1 B:DPN5 3.5 27.4 1.0
CA2 B:S7Z7 3.6 38.7 1.0
CA4 B:S7Z7 3.6 35.9 1.0
NZ A:LYS259 3.7 40.0 1.0
CB5 B:S7Z7 4.1 40.8 1.0
CA3 B:S7Z7 4.1 38.0 1.0
CB2 B:S7Z7 4.1 40.8 1.0
CZ B:DPN5 4.2 26.2 1.0
CG B:DPN5 4.4 27.7 1.0
CE A:LYS259 4.6 38.5 1.0
FA2 B:S7Z7 4.7 39.7 1.0
FB2 B:S7Z7 4.8 41.4 1.0
CB4 B:S7Z7 4.8 41.0 1.0
CB3 B:S7Z7 4.8 40.9 1.0
CA B:S7Z7 4.9 31.9 1.0
CE2 B:DPN5 4.9 26.4 1.0

Fluorine binding site 3 out of 4 in 7axs

Go back to Fluorine Binding Sites List in 7axs
Fluorine binding site 3 out of 4 in the Structural Characterisation of WDR5:Cs-VIP8 Interaction in Cis State 1


Mono view


Stereo pair view

A full contact list of Fluorine with other atoms in the F binding site number 3 of Structural Characterisation of WDR5:Cs-VIP8 Interaction in Cis State 1 within 5.0Å range:
probe atom residue distance (Å) B Occ
B:F7

b:41.4
occ:1.00
FB2 B:S7Z7 0.0 41.4 1.0
CB2 B:S7Z7 1.4 40.8 1.0
CB3 B:S7Z7 2.4 40.9 1.0
CB1 B:S7Z7 2.4 41.2 1.0
NB1 B:S7Z7 2.8 40.2 1.0
NA1 B:S7Z7 3.5 41.1 1.0
CA1 B:S7Z7 3.6 39.7 1.0
CB6 B:S7Z7 3.6 41.5 1.0
CB4 B:S7Z7 3.6 41.0 1.0
CA2 B:S7Z7 3.7 38.7 1.0
FA2 B:S7Z7 3.7 39.7 1.0
O B:HOH110 3.8 41.0 1.0
CB5 B:S7Z7 4.1 40.8 1.0
CA6 B:S7Z7 4.3 39.0 1.0
CA3 B:S7Z7 4.5 38.0 1.0
FA6 B:S7Z7 4.8 40.9 1.0
FB6 B:S7Z7 4.8 41.4 1.0
O B:HOH104 5.0 28.5 1.0

Fluorine binding site 4 out of 4 in 7axs

Go back to Fluorine Binding Sites List in 7axs
Fluorine binding site 4 out of 4 in the Structural Characterisation of WDR5:Cs-VIP8 Interaction in Cis State 1


Mono view


Stereo pair view

A full contact list of Fluorine with other atoms in the F binding site number 4 of Structural Characterisation of WDR5:Cs-VIP8 Interaction in Cis State 1 within 5.0Å range:
probe atom residue distance (Å) B Occ
B:F7

b:41.4
occ:1.00
FB6 B:S7Z7 0.0 41.4 1.0
CB6 B:S7Z7 1.4 41.5 1.0
CB5 B:S7Z7 2.4 40.8 1.0
CB1 B:S7Z7 2.4 41.2 1.0
NB1 B:S7Z7 2.8 40.2 1.0
FA6 B:S7Z7 3.2 40.9 1.0
O B:HOH111 3.4 55.9 1.0
CB2 B:S7Z7 3.7 40.8 1.0
NA1 B:S7Z7 3.7 41.1 1.0
CB4 B:S7Z7 3.7 41.0 1.0
CB3 B:S7Z7 4.2 40.9 1.0
CA6 B:S7Z7 4.2 39.0 1.0
CA1 B:S7Z7 4.4 39.7 1.0
NZ A:LYS259 4.8 40.0 1.0
FB2 B:S7Z7 4.8 41.4 1.0
CB B:S7Z7 4.9 41.1 1.0
OB B:S7Z7 4.9 40.6 1.0
CE1 B:DPN5 4.9 26.5 1.0
CD1 B:DPN5 5.0 27.4 1.0

Reference:

L.Albert, J.Nagpal, W.Steinchen, L.Zhang, L.Werel, N.Djokovic, D.Ruzic, M.Hoffarth, J.Xu, J.Kaspareit, F.Abendroth, A.Royant, G.Bange, K.Nikolic, S.Ryu, Y.Dou, L.-O.Essen, O.Vazquez. Bistable Photoswitch Allows in Vivo Control of Hematopoiesis To Be Published.
Page generated: Tue Jul 15 18:40:22 2025

Last articles

Fe in 2YXO
Fe in 2YRS
Fe in 2YXC
Fe in 2YNM
Fe in 2YVJ
Fe in 2YP1
Fe in 2YU2
Fe in 2YU1
Fe in 2YQB
Fe in 2YOO
© Copyright 2008-2020 by atomistry.com
Home   |    Site Map   |    Copyright   |    Contact us   |    Privacy