Fluorine in PDB 7aym: Structure of DDR2 Kinase Domain in Complex with IBZ3

All present enzymatic activity of Structure of DDR2 Kinase Domain in Complex with IBZ3:
2.7.10.1;

The structure of Structure of DDR2 Kinase Domain in Complex with IBZ3, PDB code: 7aym was solved by A.Nawrotek, A.Talagas, L.M.Vuillard, L.Miallau, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	61.78 / 2.12
Space group	P 21 21 21
Cell size a, b, c (Å), α, β, γ (°)	41.750, 85.355, 89.541, 90.00, 90.00, 90.00
R / Rfree (%)	23.6 / 28.9

The binding sites of Fluorine atom in the Structure of DDR2 Kinase Domain in Complex with IBZ3 (pdb code 7aym). This binding sites where shown within 5.0 Angstroms radius around Fluorine atom.
In total only one binding site of Fluorine was determined in the Structure of DDR2 Kinase Domain in Complex with IBZ3, PDB code: 7aym:

Fluorine binding site 1 out of 1 in the Structure of DDR2 Kinase Domain in Complex with IBZ3


Mono view


Stereo pair view

A full contact list of Fluorine with other atoms in the F binding site number 1 of Structure of DDR2 Kinase Domain in Complex with IBZ3 within 5.0Å range: probe atom residue distance (Å) B Occ A:F901 b:47.4 occ:1.00 F16 A:4VD901 0.0 47.4 1.0 C15 A:4VD901 1.4 51.0 1.0 C17 A:4VD901 2.3 54.4 1.0 C14 A:4VD901 2.3 54.4 1.0 H44 A:4VD901 2.5 54.5 1.0 H43 A:4VD901 2.6 54.5 1.0 C13 A:4VD901 3.6 54.4 1.0 C11 A:4VD901 3.6 54.0 1.0 CD2 A:HIS717 3.6 22.0 1.0 CD1 A:LEU710 3.9 20.5 1.0 O A:ILE735 3.9 14.9 1.0 NE2 A:HIS717 3.9 21.6 1.0 CD2 A:LEU710 4.0 24.9 1.0 CD1 A:ILE637 4.0 19.1 1.0 C12 A:4VD901 4.1 54.4 1.0 C A:ILE735 4.3 13.5 1.0 CG2 A:ILE637 4.3 15.2 1.0 O A:ALA736 4.4 13.2 1.0 CG2 A:ILE735 4.4 12.9 1.0 CG A:LEU710 4.5 21.0 1.0 H42 A:4VD901 4.5 54.5 1.0 C A:ALA736 4.5 13.9 1.0 CA A:ALA736 4.6 7.3 1.0 N A:ALA736 4.6 7.9 1.0 CB A:ILE735 4.6 14.1 1.0 H40 A:4VD901 4.6 54.5 1.0 N10 A:4VD901 4.7 54.4 1.0 CG A:HIS717 4.8 20.4 1.0 CD2 A:LEU632 4.9 23.9 1.0 CD1 A:LEU632 4.9 21.7 1.0

A.Nawrotek, A.Talagas, L.M.Vuillard, L.Miallau. Structure of DDR2 Kinase Domain in Complex with IBZ3 To Be Published.