Fluorine in PDB 7b41: Crystal Structure of C-Met Bound By Compound 7

All present enzymatic activity of Crystal Structure of C-Met Bound By Compound 7:
2.7.10.1;

The structure of Crystal Structure of C-Met Bound By Compound 7, PDB code: 7b41 was solved by G.W.Collie, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	47.31 / 1.97
Space group	C 1 2 1
Cell size a, b, c (Å), α, β, γ (°)	111.670, 42.620, 86.440, 90.00, 122.07, 90.00
R / Rfree (%)	19.6 / 23.3

The binding sites of Fluorine atom in the Crystal Structure of C-Met Bound By Compound 7 (pdb code 7b41). This binding sites where shown within 5.0 Angstroms radius around Fluorine atom.
In total only one binding site of Fluorine was determined in the Crystal Structure of C-Met Bound By Compound 7, PDB code: 7b41:

Fluorine binding site 1 out of 1 in the Crystal Structure of C-Met Bound By Compound 7


Mono view


Stereo pair view

A full contact list of Fluorine with other atoms in the F binding site number 1 of Crystal Structure of C-Met Bound By Compound 7 within 5.0Å range: probe atom residue distance (Å) B Occ A:F1401 b:56.9 occ:1.00 F A:SWK1401 0.0 56.9 1.0 C A:SWK1401 1.3 51.7 1.0 C1 A:SWK1401 2.3 49.9 1.0 C5 A:SWK1401 2.3 45.9 1.0 C6 A:SWK1401 2.9 40.7 1.0 CG2 A:VAL1092 3.5 45.1 1.0 CB A:VAL1092 3.5 45.2 1.0 C2 A:SWK1401 3.6 50.4 1.0 C4 A:SWK1401 3.6 47.7 1.0 CG1 A:VAL1092 3.6 45.2 1.0 C7 A:SWK1401 3.7 31.4 1.0 O A:PHE1089 3.8 57.9 1.0 CB A:PHE1089 3.8 56.8 1.0 C3 A:SWK1401 4.1 49.4 1.0 C8 A:SWK1401 4.3 27.6 1.0 CD2 A:PHE1089 4.4 58.2 1.0 CG A:PHE1089 4.5 56.9 1.0 O A:MET1229 4.5 53.0 1.0 C13 A:SWK1401 4.7 27.1 1.0 C A:PHE1089 4.7 59.1 1.0 CD A:LYS1110 4.8 68.3 1.0 CA A:PHE1089 4.9 56.2 1.0 CG A:MET1229 4.9 60.5 1.0

G.W.Collie, G.W.Collie. N/A N/A.
DOI: 10.1021/ACSMEDCHEMLETT.0C00392