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Fluorine in PDB 7ce4: TANKYRASE2 Catalytic Domain in Complex with K-476Enzymatic activity of TANKYRASE2 Catalytic Domain in Complex with K-476
All present enzymatic activity of TANKYRASE2 Catalytic Domain in Complex with K-476:
2.4.2.30; Protein crystallography data
The structure of TANKYRASE2 Catalytic Domain in Complex with K-476, PDB code: 7ce4
was solved by
Y.Takahashi,
M.Suzuki,
J.Saito,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Other elements in 7ce4:
The structure of TANKYRASE2 Catalytic Domain in Complex with K-476 also contains other interesting chemical elements:
Fluorine Binding Sites:
The binding sites of Fluorine atom in the TANKYRASE2 Catalytic Domain in Complex with K-476
(pdb code 7ce4). This binding sites where shown within
5.0 Angstroms radius around Fluorine atom.
In total only one binding site of Fluorine was determined in the TANKYRASE2 Catalytic Domain in Complex with K-476, PDB code: 7ce4: Fluorine binding site 1 out of 1 in 7ce4Go back to Fluorine Binding Sites List in 7ce4
Fluorine binding site 1 out
of 1 in the TANKYRASE2 Catalytic Domain in Complex with K-476
Mono view Stereo pair view
Reference:
H.Kinosada,
R.Okada-Iwasaki,
K.Kunieda,
M.Suzuki-Imaizumi,
Y.Takahashi,
H.Miyagi,
M.Suzuki,
K.Motosawa,
M.Watanabe,
M.Mie,
T.Ishii,
H.Ishida,
J.I.Saito,
R.Nakai.
The Dual Pocket Binding Novel Tankyrase Inhibitor K-476 Enhances the Efficacy of Immune Checkpoint Inhibitor By Attracting CD8 + T Cells to Tumors. Am J Cancer Res V. 11 264 2021.
Page generated: Sat Jul 10 14:05:03 2021
ISSN: ISSN 2156-6976 PubMed: 33520373 |
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