Fluorine in PDB 7cky: Cryo-Em Structure of PW0464 Bound Dopamine Receptor DRD1-Gs Signaling Complex

Fluorine Binding Sites:

The binding sites of Fluorine atom in the Cryo-Em Structure of PW0464 Bound Dopamine Receptor DRD1-Gs Signaling Complex (pdb code 7cky). This binding sites where shown within 5.0 Angstroms radius around Fluorine atom.
In total 2 binding sites of Fluorine where determined in the Cryo-Em Structure of PW0464 Bound Dopamine Receptor DRD1-Gs Signaling Complex, PDB code: 7cky:
Jump to Fluorine binding site number: 1; 2;

Fluorine binding site 1 out of 2 in 7cky

Go back to Fluorine Binding Sites List in 7cky
Fluorine binding site 1 out of 2 in the Cryo-Em Structure of PW0464 Bound Dopamine Receptor DRD1-Gs Signaling Complex


Mono view


Stereo pair view

A full contact list of Fluorine with other atoms in the F binding site number 1 of Cryo-Em Structure of PW0464 Bound Dopamine Receptor DRD1-Gs Signaling Complex within 5.0Å range:
probe atom residue distance (Å) B Occ
R:F502

b:46.4
occ:1.00
F01 R:G3U502 0.0 46.4 1.0
C02 R:G3U502 1.4 46.4 1.0
F03 R:G3U502 2.2 46.4 1.0
O04 R:G3U502 2.3 46.4 1.0
OG R:SER198 2.7 47.5 1.0
O R:SER198 3.2 47.5 1.0
CA R:SER199 3.2 41.1 1.0
C R:SER198 3.2 47.5 1.0
N R:SER199 3.2 41.1 1.0
CB R:SER202 3.3 37.8 1.0
C05 R:G3U502 3.3 46.4 1.0
OG R:SER199 3.5 41.1 1.0
OG R:SER202 3.5 37.8 1.0
C06 R:G3U502 3.7 46.4 1.0
CE1 R:PHE289 3.8 41.7 1.0
CB R:SER198 3.8 47.5 1.0
CB R:SER199 3.9 41.1 1.0
CA R:SER198 4.1 47.5 1.0
C R:SER199 4.4 41.1 1.0
C10 R:G3U502 4.5 46.4 1.0
CZ R:PHE289 4.6 41.7 1.0
CD1 R:PHE289 4.7 41.7 1.0
CA R:SER202 4.7 37.8 1.0
CG2 R:ILE154 4.8 50.3 1.0
O R:SER199 4.8 41.1 1.0
O11 R:G3U502 4.9 46.4 1.0

Fluorine binding site 2 out of 2 in 7cky

Go back to Fluorine Binding Sites List in 7cky
Fluorine binding site 2 out of 2 in the Cryo-Em Structure of PW0464 Bound Dopamine Receptor DRD1-Gs Signaling Complex


Mono view


Stereo pair view

A full contact list of Fluorine with other atoms in the F binding site number 2 of Cryo-Em Structure of PW0464 Bound Dopamine Receptor DRD1-Gs Signaling Complex within 5.0Å range:
probe atom residue distance (Å) B Occ
R:F502

b:46.4
occ:1.00
F03 R:G3U502 0.0 46.4 1.0
C02 R:G3U502 1.4 46.4 1.0
F01 R:G3U502 2.2 46.4 1.0
O04 R:G3U502 2.3 46.4 1.0
OG R:SER199 2.7 41.1 1.0
OG R:SER198 3.2 47.5 1.0
C05 R:G3U502 3.2 46.4 1.0
OD1 R:ASN292 3.3 48.0 1.0
CD1 R:LEU190 3.4 54.7 1.0
ND2 R:ASN292 3.5 48.0 1.0
CG R:ASN292 3.7 48.0 1.0
N R:SER199 3.7 41.1 1.0
O11 R:G3U502 3.7 46.4 1.0
CB R:SER199 3.7 41.1 1.0
CA R:SER199 3.8 41.1 1.0
C10 R:G3U502 3.9 46.4 1.0
CB R:SER198 4.0 47.5 1.0
C06 R:G3U502 4.2 46.4 1.0
C R:SER198 4.2 47.5 1.0
CE1 R:PHE289 4.3 41.7 1.0
O R:ALA195 4.5 51.9 1.0
O R:SER198 4.7 47.5 1.0
CA R:SER198 4.8 47.5 1.0
CD1 R:PHE289 4.8 41.7 1.0
CG R:LEU190 4.8 54.7 1.0
CB R:ASN292 4.9 48.0 1.0
C12 R:G3U502 5.0 46.4 1.0

Reference:

P.Xiao, W.Yan, L.Gou, Y.N.Zhong, L.Kong, C.Wu, X.Wen, Y.Yuan, S.Cao, C.Qu, X.Yang, C.C.Yang, A.Xia, Z.Hu, Q.Zhang, Y.H.He, D.L.Zhang, C.Zhang, G.H.Hou, H.Liu, L.Zhu, P.Fu, S.Yang, D.M.Rosenbaum, J.P.Sun, Y.Du, L.Zhang, X.Yu, Z.Shao. Ligand Recognition and Allosteric Regulation of DRD1-Gs Signaling Complexes. Cell V. 184 943 2021.
ISSN: ISSN 1097-4172
PubMed: 33571432
DOI: 10.1016/J.CELL.2021.01.028
Page generated: Sat Apr 3 15:09:07 2021

Last articles

Zn in 8WB0
Zn in 8WAX
Zn in 8WAU
Zn in 8WAZ
Zn in 8WAY
Zn in 8WAV
Zn in 8WAW
Zn in 8WAT
Zn in 8W7M
Zn in 8WD3
© Copyright 2008-2020 by atomistry.com
Home   |    Site Map   |    Copyright   |    Contact us   |    Privacy