Fluorine in PDB 7dfz: CRYO_EM Structure of Delta N-NPC1L1-Eze

The binding sites of Fluorine atom in the CRYO_EM Structure of Delta N-NPC1L1-Eze (pdb code 7dfz). This binding sites where shown within 5.0 Angstroms radius around Fluorine atom.
In total 2 binding sites of Fluorine where determined in the CRYO_EM Structure of Delta N-NPC1L1-Eze, PDB code: 7dfz:
Jump to Fluorine binding site number: 1; 2;

Fluorine binding site 1 out of 2 in the CRYO_EM Structure of Delta N-NPC1L1-Eze


Mono view


Stereo pair view

A full contact list of Fluorine with other atoms in the F binding site number 1 of CRYO_EM Structure of Delta N-NPC1L1-Eze within 5.0Å range: probe atom residue distance (Å) B Occ A:F1306 b:85.0 occ:1.00 F1 A:H561306 0.0 85.0 1.0 C6 A:H561306 1.4 85.0 1.0 C7 A:H561306 2.3 85.0 1.0 C5 A:H561306 2.5 85.0 1.0 H7 A:H561306 2.6 85.0 1.0 H5 A:H561306 2.8 85.0 1.0 OE1 A:GLN873 3.1 90.2 1.0 CD2 A:PHE1101 3.3 90.2 1.0 CE2 A:PHE1101 3.5 90.2 1.0 C4 A:H561306 3.7 85.0 1.0 C8 A:H561306 3.7 85.0 1.0 CD A:GLN873 3.9 90.2 1.0 CG A:GLN873 4.0 90.2 1.0 OH A:TYR1102 4.1 90.2 1.0 C3 A:H561306 4.2 85.0 1.0 CG A:PHE1101 4.2 90.2 1.0 CZ A:PHE1101 4.6 90.2 1.0 H8 A:H561306 4.6 85.0 1.0 H4 A:H561306 4.6 85.0 1.0 CZ A:TYR1102 4.7 90.2 1.0 CB A:GLN873 4.7 90.2 1.0 CB A:PHE1101 4.8 90.2 1.0 CE2 A:TYR1102 4.9 90.2 1.0

Fluorine binding site 2 out of 2 in the CRYO_EM Structure of Delta N-NPC1L1-Eze


Mono view


Stereo pair view

A full contact list of Fluorine with other atoms in the F binding site number 2 of CRYO_EM Structure of Delta N-NPC1L1-Eze within 5.0Å range: probe atom residue distance (Å) B Occ A:F1306 b:85.0 occ:1.00 F2 A:H561306 0.0 85.0 1.0 C16 A:H561306 1.4 85.0 1.0 C15 A:H561306 2.3 85.0 1.0 C17 A:H561306 2.5 85.0 1.0 H15 A:H561306 2.6 85.0 1.0 H17 A:H561306 2.8 85.0 1.0 CZ A:PHE1239 3.2 77.4 1.0 CE2 A:PHE1239 3.3 77.4 1.0 CG2 A:VAL1166 3.6 90.2 1.0 C18 A:H561306 3.7 85.0 1.0 C14 A:H561306 3.7 85.0 1.0 C13 A:H561306 4.2 85.0 1.0 CG1 A:VAL701 4.4 92.4 1.0 CE1 A:PHE1239 4.4 77.4 1.0 CD2 A:PHE1239 4.6 77.4 1.0 H18 A:H561306 4.6 85.0 1.0 H14 A:H561306 4.6 85.0 1.0 CD2 A:PHE772 4.7 90.2 1.0 CD2 A:LEU1234 4.7 84.9 1.0 CG A:PHE772 4.8 90.2 1.0 CE2 A:PHE772 4.9 90.2 1.0

M.Hu, F.Yang, Y.Huang, X.You, D.Liu, S.Sun, S.F.Sui. Structural Insights Into the Mechanism of Human NPC1L1-Mediated Cholesterol Uptake. Sci Adv V. 7 2021.
ISSN: ESSN 2375-2548
PubMed: 34272236
DOI: 10.1126/SCIADV.ABG3188