Fluorine in PDB 7eb2: Cryo-Em Structure of Human Gaba(B) Receptor-Gi Protein Complex

The structure of Cryo-Em Structure of Human Gaba(B) Receptor-Gi Protein Complex also contains other interesting chemical elements:

Chlorine

(Cl)

1 atom

The binding sites of Fluorine atom in the Cryo-Em Structure of Human Gaba(B) Receptor-Gi Protein Complex (pdb code 7eb2). This binding sites where shown within 5.0 Angstroms radius around Fluorine atom.
In total 3 binding sites of Fluorine where determined in the Cryo-Em Structure of Human Gaba(B) Receptor-Gi Protein Complex, PDB code: 7eb2:
Jump to Fluorine binding site number: 1; 2; 3;

Fluorine binding site 1 out of 3 in the Cryo-Em Structure of Human Gaba(B) Receptor-Gi Protein Complex


Mono view


Stereo pair view

A full contact list of Fluorine with other atoms in the F binding site number 1 of Cryo-Em Structure of Human Gaba(B) Receptor-Gi Protein Complex within 5.0Å range: probe atom residue distance (Å) B Occ D:F901 b:134.3 occ:1.00 F1 D:FN0901 0.0 134.3 1.0 C17 D:FN0901 1.3 134.3 1.0 F3 D:FN0901 2.1 134.3 1.0 F2 D:FN0901 2.1 134.3 1.0 C7 D:FN0901 2.4 134.3 1.0 O2 D:FN0901 2.6 134.3 1.0 C5 D:FN0901 3.3 134.3 1.0 CB D:LYS690 3.4 114.5 1.0 C13 D:FN0901 3.6 134.3 1.0 C9 D:FN0901 3.7 134.3 1.0 CD D:LYS690 3.7 114.5 1.0 CG D:LYS690 3.9 114.5 1.0 CA D:LYS690 4.3 114.5 1.0 O D:LYS690 4.3 114.5 1.0 O3 D:FN0901 4.3 134.3 1.0 C6 D:FN0901 4.4 134.3 1.0 O1 D:FN0901 4.5 134.3 1.0 C D:LYS690 4.5 114.5 1.0 CE D:LYS690 4.7 114.5 1.0 CE D:MET694 4.7 102.1 1.0 C4 D:FN0901 5.0 134.3 1.0

Fluorine binding site 2 out of 3 in the Cryo-Em Structure of Human Gaba(B) Receptor-Gi Protein Complex


Mono view


Stereo pair view

A full contact list of Fluorine with other atoms in the F binding site number 2 of Cryo-Em Structure of Human Gaba(B) Receptor-Gi Protein Complex within 5.0Å range: probe atom residue distance (Å) B Occ D:F901 b:134.3 occ:1.00 F2 D:FN0901 0.0 134.3 1.0 C17 D:FN0901 1.3 134.3 1.0 F3 D:FN0901 2.1 134.3 1.0 F1 D:FN0901 2.1 134.3 1.0 C7 D:FN0901 2.4 134.3 1.0 C13 D:FN0901 2.6 134.3 1.0 CB D:LYS690 2.9 114.5 1.0 O3 D:FN0901 2.9 134.3 1.0 O2 D:FN0901 3.0 134.3 1.0 C D:LYS690 3.6 114.5 1.0 O D:LYS690 3.7 114.5 1.0 O1 D:FN0901 3.7 134.3 1.0 C5 D:FN0901 3.7 134.3 1.0 CD D:LYS690 3.8 114.5 1.0 CA D:LYS690 3.8 114.5 1.0 CG D:LYS690 3.9 114.5 1.0 N D:TYR691 4.0 104.7 1.0 CE D:LYS690 4.1 114.5 1.0 CD2 D:TYR691 4.1 104.7 1.0 CE2 D:TYR691 4.2 104.7 1.0 C6 D:FN0901 4.3 134.3 1.0 CA D:TYR691 4.5 104.7 1.0 CG D:TYR691 4.6 104.7 1.0 NZ D:LYS690 4.7 114.5 1.0 CZ D:TYR691 4.7 104.7 1.0 C9 D:FN0901 4.8 134.3 1.0 CB D:MET694 4.9 102.1 1.0

Fluorine binding site 3 out of 3 in the Cryo-Em Structure of Human Gaba(B) Receptor-Gi Protein Complex


Mono view


Stereo pair view

A full contact list of Fluorine with other atoms in the F binding site number 3 of Cryo-Em Structure of Human Gaba(B) Receptor-Gi Protein Complex within 5.0Å range: probe atom residue distance (Å) B Occ D:F901 b:134.3 occ:1.00 F3 D:FN0901 0.0 134.3 1.0 C17 D:FN0901 1.3 134.3 1.0 F2 D:FN0901 2.1 134.3 1.0 F1 D:FN0901 2.1 134.3 1.0 C7 D:FN0901 2.4 134.3 1.0 C13 D:FN0901 2.9 134.3 1.0 C5 D:FN0901 3.0 134.3 1.0 O1 D:FN0901 3.3 134.3 1.0 CB D:MET694 3.4 102.1 1.0 C6 D:FN0901 3.4 134.3 1.0 CE D:MET694 3.4 102.1 1.0 O2 D:FN0901 3.5 134.3 1.0 O D:LYS690 3.7 114.5 1.0 C9 D:FN0901 3.7 134.3 1.0 CG D:MET694 3.8 102.1 1.0 O3 D:FN0901 3.9 134.3 1.0 C D:LYS690 4.2 114.5 1.0 CB D:LYS690 4.3 114.5 1.0 SD D:MET694 4.5 102.1 1.0 C2 D:FN0901 4.5 134.3 1.0 CA D:MET694 4.7 102.1 1.0 C4 D:FN0901 4.7 134.3 1.0 CA D:LYS690 4.8 114.5 1.0 N D:MET694 4.9 102.1 1.0 N D:TYR691 4.9 104.7 1.0 C8 D:FN0901 5.0 134.3 1.0

C.Shen, C.Mao, C.Xu, N.Jin, H.Zhang, D.Shen, Q.Shen, X.Wang, T.Hou, P.Rondard, Z.Chen, J.Pin, Y.Zhang, J.Liu. Structural Basis of A Distinct Mode of Gabab Receptor-Gi Protein Coupling Nature 2021.
ISSN: ESSN 1476-4687
DOI: 10.1038/S41586-021-03507-1