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Atomistry » Fluorine » PDB 7e5i-7f80 » 7ed5 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Atomistry » Fluorine » PDB 7e5i-7f80 » 7ed5 » |
Fluorine in PDB 7ed5: A Dual Mechanism of Action of at-527 Against Sars-Cov-2 PolymeraseEnzymatic activity of A Dual Mechanism of Action of at-527 Against Sars-Cov-2 Polymerase
All present enzymatic activity of A Dual Mechanism of Action of at-527 Against Sars-Cov-2 Polymerase:
2.7.7.48; Other elements in 7ed5:
The structure of A Dual Mechanism of Action of at-527 Against Sars-Cov-2 Polymerase also contains other interesting chemical elements:
Fluorine Binding Sites:
The binding sites of Fluorine atom in the A Dual Mechanism of Action of at-527 Against Sars-Cov-2 Polymerase
(pdb code 7ed5). This binding sites where shown within
5.0 Angstroms radius around Fluorine atom.
In total 3 binding sites of Fluorine where determined in the A Dual Mechanism of Action of at-527 Against Sars-Cov-2 Polymerase, PDB code: 7ed5: Jump to Fluorine binding site number: 1; 2; 3; Fluorine binding site 1 out of 3 in 7ed5Go back to Fluorine Binding Sites List in 7ed5
Fluorine binding site 1 out
of 3 in the A Dual Mechanism of Action of at-527 Against Sars-Cov-2 Polymerase
Mono view Stereo pair view
Fluorine binding site 2 out of 3 in 7ed5Go back to Fluorine Binding Sites List in 7ed5
Fluorine binding site 2 out
of 3 in the A Dual Mechanism of Action of at-527 Against Sars-Cov-2 Polymerase
Mono view Stereo pair view
Fluorine binding site 3 out of 3 in 7ed5Go back to Fluorine Binding Sites List in 7ed5
Fluorine binding site 3 out
of 3 in the A Dual Mechanism of Action of at-527 Against Sars-Cov-2 Polymerase
Mono view Stereo pair view
Reference:
A.Shannon,
V.Fattorini,
B.Sama,
B.Selisko,
M.Feracci,
C.Falcou,
P.Gauffre,
P.El Kazzi,
A.Delpal,
E.Decroly,
K.Alvarez,
C.Eydoux,
J.C.Guillemot,
A.Moussa,
S.S.Good,
P.La Colla,
K.Lin,
J.P.Sommadossi,
Y.Zhu,
X.Yan,
H.Shi,
F.Ferron,
B.Canard.
A Dual Mechanism of Action of at-527 Against Sars-Cov-2 Polymerase. Nat Commun V. 13 621 2022.
Page generated: Fri Aug 2 06:42:02 2024
ISSN: ESSN 2041-1723 PubMed: 35110538 DOI: 10.1038/S41467-022-28113-1 |
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