Fluorine in PDB 7et1: Cryo-Em Structure of the Gastric Proton Pump K791S/E820D/Y340N/E936V/Y799W Mutant in K+-Occluded (K+)E2-Alf State

The structure of Cryo-Em Structure of the Gastric Proton Pump K791S/E820D/Y340N/E936V/Y799W Mutant in K+-Occluded (K+)E2-Alf State also contains other interesting chemical elements:

Aluminium	(Al)	1 atom
Potassium	(K)	3 atoms
Magnesium	(Mg)	1 atom

The binding sites of Fluorine atom in the Cryo-Em Structure of the Gastric Proton Pump K791S/E820D/Y340N/E936V/Y799W Mutant in K+-Occluded (K+)E2-Alf State (pdb code 7et1). This binding sites where shown within 5.0 Angstroms radius around Fluorine atom.
In total 4 binding sites of Fluorine where determined in the Cryo-Em Structure of the Gastric Proton Pump K791S/E820D/Y340N/E936V/Y799W Mutant in K+-Occluded (K+)E2-Alf State, PDB code: 7et1:
Jump to Fluorine binding site number: 1; 2; 3; 4;

Fluorine binding site 1 out of 4 in the Cryo-Em Structure of the Gastric Proton Pump K791S/E820D/Y340N/E936V/Y799W Mutant in K+-Occluded (K+)E2-Alf State


Mono view


Stereo pair view

A full contact list of Fluorine with other atoms in the F binding site number 1 of Cryo-Em Structure of the Gastric Proton Pump K791S/E820D/Y340N/E936V/Y799W Mutant in K+-Occluded (K+)E2-Alf State within 5.0Å range: probe atom residue distance (Å) B Occ A:F1105 b:38.2 occ:1.00 F1 A:ALF1105 0.0 38.2 1.0 AL A:ALF1105 1.8 38.2 1.0 OD1 A:ASP385 1.8 38.5 1.0 F4 A:ALF1105 2.5 38.2 1.0 F3 A:ALF1105 2.5 38.2 1.0 O A:HOH1201 2.6 33.7 1.0 N A:THR387 2.6 38.5 1.0 N A:LYS386 2.8 38.5 1.0 CG A:ASP385 2.8 38.5 1.0 OG1 A:THR626 3.1 38.5 1.0 CA A:LYS386 3.3 38.5 1.0 OD2 A:ASP385 3.4 38.5 1.0 C A:LYS386 3.4 38.5 1.0 CB A:LYS386 3.5 38.5 1.0 F2 A:ALF1105 3.6 38.2 1.0 CB A:THR387 3.6 38.5 1.0 CA A:THR387 3.6 38.5 1.0 OG1 A:THR387 3.6 38.5 1.0 C A:ASP385 3.8 38.5 1.0 CB A:THR626 3.9 38.5 1.0 CB A:ASP385 4.0 38.5 1.0 O A:THR387 4.1 38.5 1.0 CA A:ASP385 4.1 38.5 1.0 CA A:THR626 4.1 38.5 1.0 OE2 A:GLU230 4.3 45.6 1.0 C A:THR387 4.3 38.5 1.0 MG A:MG1101 4.5 38.5 1.0 N A:GLY627 4.5 38.5 1.0 O A:LYS386 4.6 38.5 1.0 O A:VAL625 4.6 38.5 1.0 NZ A:LYS707 4.8 38.5 1.0 CG A:LYS386 4.8 38.5 1.0 O A:ASP385 4.9 38.5 1.0 C A:THR626 4.9 38.5 1.0

Fluorine binding site 2 out of 4 in the Cryo-Em Structure of the Gastric Proton Pump K791S/E820D/Y340N/E936V/Y799W Mutant in K+-Occluded (K+)E2-Alf State


Mono view


Stereo pair view

A full contact list of Fluorine with other atoms in the F binding site number 2 of Cryo-Em Structure of the Gastric Proton Pump K791S/E820D/Y340N/E936V/Y799W Mutant in K+-Occluded (K+)E2-Alf State within 5.0Å range: probe atom residue distance (Å) B Occ A:F1105 b:38.2 occ:1.00 F2 A:ALF1105 0.0 38.2 1.0 AL A:ALF1105 1.8 38.2 1.0 F4 A:ALF1105 2.5 38.2 1.0 F3 A:ALF1105 2.5 38.2 1.0 ND2 A:ASN729 2.7 38.8 1.0 OD1 A:ASP385 3.0 38.5 1.0 OD1 A:ASN729 3.1 38.8 1.0 O A:HOH1201 3.2 33.7 1.0 CG A:ASN729 3.2 38.8 1.0 CA A:GLY229 3.4 41.4 1.0 NZ A:LYS707 3.5 38.5 1.0 OD2 A:ASP730 3.5 38.5 1.0 CG A:ASP385 3.5 38.5 1.0 MG A:MG1101 3.5 38.5 1.0 F1 A:ALF1105 3.6 38.2 1.0 OD2 A:ASP385 3.6 38.5 1.0 OD1 A:ASP730 3.6 38.5 1.0 O A:THR228 3.8 40.8 1.0 CG A:ASP730 3.9 38.5 1.0 N A:GLY229 4.0 41.4 1.0 C A:THR228 4.2 40.8 1.0 C A:GLY229 4.5 41.4 1.0 CE A:LYS707 4.6 38.5 1.0 O A:GLY229 4.6 41.4 1.0 CB A:ASN729 4.6 38.8 1.0 CB A:ASP385 4.7 38.5 1.0 OE2 A:GLU230 5.0 45.6 1.0

Fluorine binding site 3 out of 4 in the Cryo-Em Structure of the Gastric Proton Pump K791S/E820D/Y340N/E936V/Y799W Mutant in K+-Occluded (K+)E2-Alf State


Mono view


Stereo pair view

A full contact list of Fluorine with other atoms in the F binding site number 3 of Cryo-Em Structure of the Gastric Proton Pump K791S/E820D/Y340N/E936V/Y799W Mutant in K+-Occluded (K+)E2-Alf State within 5.0Å range: probe atom residue distance (Å) B Occ A:F1105 b:38.2 occ:1.00 F3 A:ALF1105 0.0 38.2 1.0 AL A:ALF1105 1.8 38.2 1.0 MG A:MG1101 1.9 38.5 1.0 OD2 A:ASP385 2.1 38.5 1.0 OD1 A:ASP385 2.4 38.5 1.0 O A:THR387 2.5 38.5 1.0 F1 A:ALF1105 2.5 38.2 1.0 F2 A:ALF1105 2.5 38.2 1.0 CG A:ASP385 2.6 38.5 1.0 O A:HOH1201 3.3 33.7 1.0 N A:THR387 3.4 38.5 1.0 C A:THR387 3.4 38.5 1.0 CB A:THR387 3.4 38.5 1.0 CA A:THR387 3.6 38.5 1.0 F4 A:ALF1105 3.6 38.2 1.0 OD1 A:ASP726 3.6 38.5 1.0 CB A:ASP385 4.1 38.5 1.0 O A:GLY229 4.1 41.4 1.0 OD2 A:ASP730 4.2 38.5 1.0 CA A:GLY229 4.3 41.4 1.0 OG1 A:THR387 4.3 38.5 1.0 N A:LYS386 4.4 38.5 1.0 C A:LYS386 4.4 38.5 1.0 CG2 A:THR387 4.4 38.5 1.0 OD1 A:ASP730 4.6 38.5 1.0 C A:GLY229 4.6 41.4 1.0 N A:GLY388 4.7 38.5 1.0 CG A:ASP726 4.7 38.5 1.0 OE2 A:GLU230 4.8 45.6 1.0 CG A:ASP730 4.9 38.5 1.0 C A:ASP385 4.9 38.5 1.0 CA A:LYS386 5.0 38.5 1.0 CA A:ASP385 5.0 38.5 1.0

Fluorine binding site 4 out of 4 in the Cryo-Em Structure of the Gastric Proton Pump K791S/E820D/Y340N/E936V/Y799W Mutant in K+-Occluded (K+)E2-Alf State


Mono view


Stereo pair view

A full contact list of Fluorine with other atoms in the F binding site number 4 of Cryo-Em Structure of the Gastric Proton Pump K791S/E820D/Y340N/E936V/Y799W Mutant in K+-Occluded (K+)E2-Alf State within 5.0Å range: probe atom residue distance (Å) B Occ A:F1105 b:38.2 occ:1.00 F4 A:ALF1105 0.0 38.2 1.0 AL A:ALF1105 1.8 38.2 1.0 O A:HOH1201 2.5 33.7 1.0 F1 A:ALF1105 2.5 38.2 1.0 OD1 A:ASP385 2.5 38.5 1.0 F2 A:ALF1105 2.5 38.2 1.0 NZ A:LYS707 2.9 38.5 1.0 N A:GLY627 2.9 38.5 1.0 CA A:THR626 3.3 38.5 1.0 OG1 A:THR626 3.5 38.5 1.0 C A:THR626 3.5 38.5 1.0 F3 A:ALF1105 3.6 38.2 1.0 CG A:ASP385 3.7 38.5 1.0 CE A:LYS707 3.7 38.5 1.0 O A:THR228 3.8 40.8 1.0 CB A:THR626 3.9 38.5 1.0 CA A:GLY627 3.9 38.5 1.0 ND2 A:ASN729 4.0 38.8 1.0 O A:VAL625 4.1 38.5 1.0 N A:THR626 4.4 38.5 1.0 OD2 A:ASP385 4.4 38.5 1.0 OE2 A:GLU230 4.5 45.6 1.0 OD1 A:ASP730 4.6 38.5 1.0 N A:LYS386 4.6 38.5 1.0 CB A:ASP385 4.6 38.5 1.0 O A:THR626 4.7 38.5 1.0 C A:VAL625 4.7 38.5 1.0 C A:THR228 4.8 40.8 1.0 CA A:GLY229 4.9 41.4 1.0 N A:ASP628 4.9 41.1 1.0 C A:GLY627 4.9 38.5 1.0 CA A:ASP385 4.9 38.5 1.0 CG A:ASN729 5.0 38.8 1.0

K.Abe, K.Yamamoto, K.Irie, T.Nishizawa, A.Oshima. Two K+-Bound Gastric Proton Pump Generated By the Sodium Pump-Mimetic Mutations To Be Published.