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Fluorine in PDB 7f2m: Crystal Structure of PDE4D Catalytic Domain Complexed with Compound 18DEnzymatic activity of Crystal Structure of PDE4D Catalytic Domain Complexed with Compound 18D
All present enzymatic activity of Crystal Structure of PDE4D Catalytic Domain Complexed with Compound 18D:
3.1.4.53; Protein crystallography data
The structure of Crystal Structure of PDE4D Catalytic Domain Complexed with Compound 18D, PDB code: 7f2m
was solved by
Y.-Y.Huang,
X.He,
H.-B.Luo,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Other elements in 7f2m:
The structure of Crystal Structure of PDE4D Catalytic Domain Complexed with Compound 18D also contains other interesting chemical elements:
Fluorine Binding Sites:
The binding sites of Fluorine atom in the Crystal Structure of PDE4D Catalytic Domain Complexed with Compound 18D
(pdb code 7f2m). This binding sites where shown within
5.0 Angstroms radius around Fluorine atom.
In total 2 binding sites of Fluorine where determined in the Crystal Structure of PDE4D Catalytic Domain Complexed with Compound 18D, PDB code: 7f2m: Jump to Fluorine binding site number: 1; 2; Fluorine binding site 1 out of 2 in 7f2mGo back to Fluorine Binding Sites List in 7f2m
Fluorine binding site 1 out
of 2 in the Crystal Structure of PDE4D Catalytic Domain Complexed with Compound 18D
Mono view Stereo pair view
Fluorine binding site 2 out of 2 in 7f2mGo back to Fluorine Binding Sites List in 7f2m
Fluorine binding site 2 out
of 2 in the Crystal Structure of PDE4D Catalytic Domain Complexed with Compound 18D
Mono view Stereo pair view
Reference:
Y.Y.Huang,
J.Deng,
Y.J.Tian,
J.Liang,
X.Xie,
Y.Huang,
J.Zhu,
Z.Zhu,
Q.Zhou,
X.He,
H.B.Luo.
Mangostanin Derivatives As Novel and Orally Active Phosphodiesterase 4 Inhibitors For the Treatment of Idiopathic Pulmonary Fibrosis with Improved Safety. J.Med.Chem. V. 64 13736 2021.
Page generated: Fri Nov 5 13:12:20 2021
ISSN: ISSN 0022-2623 PubMed: 34520193 DOI: 10.1021/ACS.JMEDCHEM.1C01085 |
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