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Atomistry » Fluorine » PDB 7e5i-7f80 » 7f3b | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Atomistry » Fluorine » PDB 7e5i-7f80 » 7f3b » |
Fluorine in PDB 7f3b: Cocrystallization of Escherichia Coli Dihydrofolate Reductase (Dhfr) and Its Pyrrolo[3,2-F]Quinazoline Inhibitor.Enzymatic activity of Cocrystallization of Escherichia Coli Dihydrofolate Reductase (Dhfr) and Its Pyrrolo[3,2-F]Quinazoline Inhibitor.
All present enzymatic activity of Cocrystallization of Escherichia Coli Dihydrofolate Reductase (Dhfr) and Its Pyrrolo[3,2-F]Quinazoline Inhibitor.:
1.5.1.3; Protein crystallography data
The structure of Cocrystallization of Escherichia Coli Dihydrofolate Reductase (Dhfr) and Its Pyrrolo[3,2-F]Quinazoline Inhibitor., PDB code: 7f3b
was solved by
H.Wang,
X.F.You,
X.Y.Yang,
Y.Li,
W.Hong,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Fluorine Binding Sites:
The binding sites of Fluorine atom in the Cocrystallization of Escherichia Coli Dihydrofolate Reductase (Dhfr) and Its Pyrrolo[3,2-F]Quinazoline Inhibitor.
(pdb code 7f3b). This binding sites where shown within
5.0 Angstroms radius around Fluorine atom.
In total only one binding site of Fluorine was determined in the Cocrystallization of Escherichia Coli Dihydrofolate Reductase (Dhfr) and Its Pyrrolo[3,2-F]Quinazoline Inhibitor., PDB code: 7f3b: Fluorine binding site 1 out of 1 in 7f3bGo back to![]() ![]()
Fluorine binding site 1 out
of 1 in the Cocrystallization of Escherichia Coli Dihydrofolate Reductase (Dhfr) and Its Pyrrolo[3,2-F]Quinazoline Inhibitor.
![]() Mono view ![]() Stereo pair view
Reference:
Y.Li,
Y.Ouyang,
H.Wu,
P.Wang,
Y.Huang,
X.Li,
H.Chen,
Y.Sun,
X.Hu,
X.Wang,
G.Li,
Y.Lu,
C.Li,
X.Lu,
J.Pang,
T.Nie,
X.Sang,
L.Dong,
W.Dong,
J.Jiang,
I.C.Paterson,
X.Yang,
W.Hong,
H.Wang,
X.You.
The Discovery of 1, 3-Diamino-7H-Pyrrol[3, 2-F]Quinazoline Compounds As Potent Antimicrobial Antifolates. Eur.J.Med.Chem. V. 228 13979 2022.
Page generated: Fri Aug 2 06:49:34 2024
ISSN: ISSN 0223-5234 PubMed: 34802838 DOI: 10.1016/J.EJMECH.2021.113979 |
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