Atomistry » Fluorine » PDB 7g65-7gb3 » 7g6z
Atomistry »
  Fluorine »
    PDB 7g65-7gb3 »
      7g6z »

Fluorine in PDB 7g6z: Crystal Structure of Rat Autotaxin in Complex with 2-Chloro-7-[(4- Fluorophenyl)Methyl]-9-Methylpurin-8-One

Enzymatic activity of Crystal Structure of Rat Autotaxin in Complex with 2-Chloro-7-[(4- Fluorophenyl)Methyl]-9-Methylpurin-8-One

All present enzymatic activity of Crystal Structure of Rat Autotaxin in Complex with 2-Chloro-7-[(4- Fluorophenyl)Methyl]-9-Methylpurin-8-One:
3.1.4.39;

Protein crystallography data

The structure of Crystal Structure of Rat Autotaxin in Complex with 2-Chloro-7-[(4- Fluorophenyl)Methyl]-9-Methylpurin-8-One, PDB code: 7g6z was solved by M.Stihle, J.Benz, D.Hunziker, M.G.Rudolph, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å) 48.99 / 1.53
Space group P 21 21 21
Cell size a, b, c (Å), α, β, γ (°) 84.304, 92.277, 120.397, 90, 90, 90
R / Rfree (%) 20.8 / 24

Other elements in 7g6z:

The structure of Crystal Structure of Rat Autotaxin in Complex with 2-Chloro-7-[(4- Fluorophenyl)Methyl]-9-Methylpurin-8-One also contains other interesting chemical elements:

Zinc (Zn) 1 atom
Chlorine (Cl) 2 atoms
Potassium (K) 1 atom
Calcium (Ca) 1 atom
Sodium (Na) 1 atom

Fluorine Binding Sites:

The binding sites of Fluorine atom in the Crystal Structure of Rat Autotaxin in Complex with 2-Chloro-7-[(4- Fluorophenyl)Methyl]-9-Methylpurin-8-One (pdb code 7g6z). This binding sites where shown within 5.0 Angstroms radius around Fluorine atom.
In total only one binding site of Fluorine was determined in the Crystal Structure of Rat Autotaxin in Complex with 2-Chloro-7-[(4- Fluorophenyl)Methyl]-9-Methylpurin-8-One, PDB code: 7g6z:

Fluorine binding site 1 out of 1 in 7g6z

Go back to Fluorine Binding Sites List in 7g6z
Fluorine binding site 1 out of 1 in the Crystal Structure of Rat Autotaxin in Complex with 2-Chloro-7-[(4- Fluorophenyl)Methyl]-9-Methylpurin-8-One


Mono view


Stereo pair view

A full contact list of Fluorine with other atoms in the F binding site number 1 of Crystal Structure of Rat Autotaxin in Complex with 2-Chloro-7-[(4- Fluorophenyl)Methyl]-9-Methylpurin-8-One within 5.0Å range:
probe atom residue distance (Å) B Occ
A:F901

b:24.3
occ:1.00
F32 A:Y76901 0.0 24.3 1.0
C16 A:Y76901 1.4 24.2 1.0
C17 A:Y76901 2.3 23.2 1.0
C15 A:Y76901 2.4 24.4 1.0
CG2 A:ILE167 3.4 13.6 1.0
C18 A:Y76901 3.6 23.5 1.0
C14 A:Y76901 3.7 23.2 1.0
CB A:SER169 3.8 15.6 1.0
CD1 A:LEU216 4.0 16.8 1.0
C13 A:Y76901 4.1 23.0 1.0
OG A:SER169 4.2 18.6 1.0
CB A:LEU216 4.2 12.6 1.0
CG1 A:VAL356 4.2 12.5 1.0
CD2 A:LEU213 4.6 15.6 1.0
CG A:LEU216 4.7 14.7 1.0
CB A:ILE167 4.7 14.2 1.0

Reference:

D.Hunziker, S.C.Joachim, C.Ullmer, M.G.Rudolph. Crystal Structure of A Rat Autotaxin Complex To Be Published.
Page generated: Sat Feb 8 18:05:16 2025

Last articles

As in 5FVY
As in 5FJ3
As in 5FJ2
As in 5EG5
As in 5DBX
As in 5BO4
As in 5E93
As in 5ED4
As in 5E64
As in 5E66
© Copyright 2008-2020 by atomistry.com
Home   |    Site Map   |    Copyright   |    Contact us   |    Privacy