Fluorine in PDB 7m04: Structure of Sars-Cov-2 3CL Protease in Complex with Inhibitor 21C

All present enzymatic activity of Structure of Sars-Cov-2 3CL Protease in Complex with Inhibitor 21C:
3.4.22.69;

The structure of Structure of Sars-Cov-2 3CL Protease in Complex with Inhibitor 21C, PDB code: 7m04 was solved by S.Lovell, M.M.Kashipathy, K.P.Battaile, S.D.Chamandi, A.D.Rathnayake, Y.Kim, K.D.Perera, A.R.M.Jesri, H.N.Nguyen, M.A.Baird, M.J.Miller, W.C.Groutas, K.O.Chang, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	46.43 / 1.75
Space group	P 1 21 1
Cell size a, b, c (Å), α, β, γ (°)	55.299, 98.825, 58.856, 90, 108, 90
R / Rfree (%)	18 / 22.3

Pages:

>>> Page 1 <<< Page 2, Binding sites: 11 - 20;

Binding sites:

The binding sites of Fluorine atom in the Structure of Sars-Cov-2 3CL Protease in Complex with Inhibitor 21C (pdb code 7m04). This binding sites where shown within 5.0 Angstroms radius around Fluorine atom.
In total 20 binding sites of Fluorine where determined in the Structure of Sars-Cov-2 3CL Protease in Complex with Inhibitor 21C, PDB code: 7m04:
Jump to Fluorine binding site number: 1; 2; 3; 4; 5; 6; 7; 8; 9; 10;

Fluorine binding site 1 out of 20 in the Structure of Sars-Cov-2 3CL Protease in Complex with Inhibitor 21C


Mono view


Stereo pair view

A full contact list of Fluorine with other atoms in the F binding site number 1 of Structure of Sars-Cov-2 3CL Protease in Complex with Inhibitor 21C within 5.0Å range: probe atom residue distance (Å) B Occ A:F401 b:45.4 occ:0.50 F24 A:YLV401 0.0 45.4 0.5 F24 A:YM1402 0.1 45.4 0.5 C23 A:YM1402 1.3 44.2 0.5 C23 A:YLV401 1.4 44.2 0.5 C22 A:YM1402 2.3 42.5 0.5 C25 A:YM1402 2.3 43.0 0.5 C22 A:YLV401 2.4 42.5 0.5 C25 A:YLV401 2.4 43.0 0.5 F26 A:YM1402 2.7 49.0 0.5 F26 A:YLV401 2.8 49.0 0.5 C21 A:YLV401 2.8 40.4 0.5 C21 A:YM1402 2.8 40.3 0.5 N A:THR190 2.9 27.4 1.0 C A:GLN189 3.0 34.9 1.0 CD A:GLN189 3.1 31.2 1.0 NE2 A:GLN189 3.1 38.4 1.0 CA A:GLN189 3.2 34.8 1.0 O20 A:YLV401 3.3 35.3 0.5 O20 A:YM1402 3.3 35.3 0.5 CG A:GLN189 3.3 34.4 1.0 O A:THR190 3.3 28.8 1.0 C A:THR190 3.4 29.7 1.0 CA A:THR190 3.6 30.9 1.0 C31 A:YM1402 3.6 49.7 0.5 C27 A:YM1402 3.6 52.5 0.5 C31 A:YLV401 3.6 49.6 0.5 C27 A:YLV401 3.7 52.5 0.5 OE1 A:GLN189 3.7 33.7 1.0 O A:GLN189 3.7 33.2 1.0 CB A:GLN189 3.8 36.1 1.0 C29 A:YM1402 4.1 51.3 0.5 C29 A:YLV401 4.1 51.3 0.5 C19 A:YLV401 4.2 36.4 0.5 C19 A:YM1402 4.2 36.4 0.5 N A:ALA191 4.2 34.1 1.0 N18 A:YLV401 4.3 28.4 0.5 O A:ARG188 4.3 27.3 1.0 N18 A:YM1402 4.3 28.5 0.5 N A:GLN189 4.5 28.7 1.0 O A:HOH548 4.6 30.1 1.0 F28 A:YM1402 4.7 61.9 0.5 F32 A:YM1402 4.7 47.9 0.5 F32 A:YLV401 4.8 47.8 0.5 F28 A:YLV401 4.8 61.9 0.5 C A:ARG188 4.8 32.2 1.0 CA A:ALA191 4.9 33.9 1.0

Fluorine binding site 2 out of 20 in the Structure of Sars-Cov-2 3CL Protease in Complex with Inhibitor 21C


Mono view


Stereo pair view

A full contact list of Fluorine with other atoms in the F binding site number 2 of Structure of Sars-Cov-2 3CL Protease in Complex with Inhibitor 21C within 5.0Å range: probe atom residue distance (Å) B Occ A:F401 b:49.0 occ:0.50 F26 A:YLV401 0.0 49.0 0.5 F26 A:YM1402 0.1 49.0 0.5 C25 A:YM1402 1.3 43.0 0.5 C25 A:YLV401 1.4 43.0 0.5 C27 A:YM1402 2.3 52.5 0.5 C27 A:YLV401 2.4 52.5 0.5 C23 A:YLV401 2.4 44.2 0.5 C23 A:YM1402 2.4 44.2 0.5 F28 A:YM1402 2.7 61.9 0.5 F28 A:YLV401 2.8 61.9 0.5 F24 A:YLV401 2.8 45.4 0.5 F24 A:YM1402 2.8 45.4 0.5 O A:HOH538 3.3 47.5 1.0 N A:ALA191 3.4 34.1 1.0 C A:THR190 3.4 29.7 1.0 CA A:THR190 3.5 30.9 1.0 C29 A:YM1402 3.6 51.3 0.5 C29 A:YLV401 3.6 51.3 0.5 C22 A:YM1402 3.6 42.5 0.5 C22 A:YLV401 3.7 42.5 0.5 O A:GLN189 3.7 33.2 1.0 O A:HOH563 3.8 32.0 1.0 N A:THR190 3.8 27.4 1.0 C A:GLN189 3.8 34.9 1.0 C31 A:YM1402 4.1 49.7 0.5 O A:THR190 4.1 28.8 1.0 C31 A:YLV401 4.1 49.6 0.5 CA A:ALA191 4.2 33.9 1.0 CG A:GLN189 4.3 34.4 1.0 CB A:ALA191 4.4 31.3 1.0 NE2 A:GLN189 4.5 38.4 1.0 F30 A:YM1402 4.7 50.5 0.5 F30 A:YLV401 4.8 50.5 0.5 CD A:GLN189 4.8 31.2 1.0 CA A:GLN189 4.8 34.8 1.0 CB A:THR190 4.9 35.6 1.0 C21 A:YLV401 4.9 40.4 0.5 C21 A:YM1402 4.9 40.3 0.5

Fluorine binding site 3 out of 20 in the Structure of Sars-Cov-2 3CL Protease in Complex with Inhibitor 21C


Mono view


Stereo pair view

A full contact list of Fluorine with other atoms in the F binding site number 3 of Structure of Sars-Cov-2 3CL Protease in Complex with Inhibitor 21C within 5.0Å range: probe atom residue distance (Å) B Occ A:F401 b:61.9 occ:0.50 F28 A:YLV401 0.0 61.9 0.5 F28 A:YM1402 0.1 61.9 0.5 C27 A:YLV401 1.4 52.5 0.5 C27 A:YM1402 1.4 52.5 0.5 C29 A:YM1402 2.3 51.3 0.5 C29 A:YLV401 2.4 51.3 0.5 C25 A:YLV401 2.4 43.0 0.5 C25 A:YM1402 2.5 43.0 0.5 F30 A:YM1402 2.7 50.5 0.5 F30 A:YLV401 2.8 50.5 0.5 F26 A:YLV401 2.8 49.0 0.5 F26 A:YM1402 2.9 49.0 0.5 CB A:ALA191 3.5 31.3 1.0 C31 A:YM1402 3.6 49.7 0.5 C31 A:YLV401 3.7 49.6 0.5 C23 A:YLV401 3.7 44.2 0.5 C23 A:YM1402 3.7 44.2 0.5 CA A:ALA191 4.1 33.9 1.0 C22 A:YLV401 4.2 42.5 0.5 C22 A:YM1402 4.2 42.5 0.5 N A:ALA191 4.2 34.1 1.0 O A:HOH563 4.6 32.0 1.0 F32 A:YM1402 4.7 47.9 0.5 F32 A:YLV401 4.8 47.8 0.5 F24 A:YLV401 4.8 45.4 0.5 F24 A:YM1402 4.8 45.4 0.5 C A:THR190 4.9 29.7 1.0

Fluorine binding site 4 out of 20 in the Structure of Sars-Cov-2 3CL Protease in Complex with Inhibitor 21C


Mono view


Stereo pair view

A full contact list of Fluorine with other atoms in the F binding site number 4 of Structure of Sars-Cov-2 3CL Protease in Complex with Inhibitor 21C within 5.0Å range: probe atom residue distance (Å) B Occ A:F401 b:50.5 occ:0.50 F30 A:YLV401 0.0 50.5 0.5 F30 A:YM1402 0.2 50.5 0.5 C29 A:YLV401 1.4 51.3 0.5 C29 A:YM1402 1.4 51.3 0.5 C27 A:YLV401 2.4 52.5 0.5 C31 A:YLV401 2.4 49.6 0.5 C31 A:YM1402 2.4 49.7 0.5 C27 A:YM1402 2.5 52.5 0.5 F32 A:YM1402 2.7 47.9 0.5 F28 A:YLV401 2.8 61.9 0.5 F32 A:YLV401 2.8 47.8 0.5 F28 A:YM1402 2.8 61.9 0.5 CG A:PRO168 3.6 37.7 1.0 C25 A:YLV401 3.7 43.0 0.5 C22 A:YLV401 3.7 42.5 0.5 C22 A:YM1402 3.7 42.5 0.5 C25 A:YM1402 3.7 43.0 0.5 CB A:PRO168 3.8 32.9 1.0 CA A:PRO168 3.8 33.3 1.0 C23 A:YLV401 4.2 44.2 0.5 N A:PRO168 4.2 31.8 1.0 C23 A:YM1402 4.2 44.2 0.5 CD A:PRO168 4.3 34.1 1.0 CB A:ALA191 4.5 31.3 1.0 F26 A:YLV401 4.8 49.0 0.5 CA A:ALA191 4.8 33.9 1.0 F26 A:YM1402 4.8 49.0 0.5 C A:LEU167 4.9 34.4 1.0 C21 A:YLV401 5.0 40.4 0.5 C21 A:YM1402 5.0 40.3 0.5

Fluorine binding site 5 out of 20 in the Structure of Sars-Cov-2 3CL Protease in Complex with Inhibitor 21C


Mono view


Stereo pair view

A full contact list of Fluorine with other atoms in the F binding site number 5 of Structure of Sars-Cov-2 3CL Protease in Complex with Inhibitor 21C within 5.0Å range: probe atom residue distance (Å) B Occ A:F401 b:47.8 occ:0.50 F32 A:YLV401 0.0 47.8 0.5 F32 A:YM1402 0.1 47.9 0.5 C31 A:YLV401 1.4 49.6 0.5 C31 A:YM1402 1.4 49.7 0.5 C29 A:YLV401 2.4 51.3 0.5 C22 A:YLV401 2.4 42.5 0.5 C22 A:YM1402 2.4 42.5 0.5 C29 A:YM1402 2.4 51.3 0.5 F30 A:YLV401 2.8 50.5 0.5 F30 A:YM1402 2.8 50.5 0.5 C21 A:YLV401 2.9 40.4 0.5 C21 A:YM1402 2.9 40.3 0.5 O A:GLU166 3.2 34.1 1.0 O20 A:YLV401 3.6 35.3 0.5 C27 A:YLV401 3.6 52.5 0.5 C23 A:YLV401 3.6 44.2 0.5 O20 A:YM1402 3.7 35.3 0.5 C23 A:YM1402 3.7 44.2 0.5 N A:PRO168 3.7 31.8 1.0 C A:LEU167 3.7 34.4 1.0 C27 A:YM1402 3.7 52.5 0.5 C A:GLU166 3.8 27.9 1.0 O A:HOH548 4.0 30.1 1.0 CA A:LEU167 4.0 21.3 1.0 O A:LEU167 4.1 30.1 1.0 CA A:PRO168 4.1 33.3 1.0 CD A:PRO168 4.1 34.1 1.0 C25 A:YLV401 4.1 43.0 0.5 C25 A:YM1402 4.2 43.0 0.5 N A:LEU167 4.3 21.0 1.0 CG A:PRO168 4.4 37.7 1.0 CB A:GLU166 4.6 29.0 1.0 C19 A:YLV401 4.7 36.4 0.5 F24 A:YLV401 4.8 45.4 0.5 F28 A:YLV401 4.8 61.9 0.5 C19 A:YM1402 4.8 36.4 0.5 F24 A:YM1402 4.8 45.4 0.5 CA A:GLU166 4.8 21.6 1.0 F28 A:YM1402 4.8 61.9 0.5 CB A:PRO168 4.8 32.9 1.0 O33 A:YLV401 4.8 31.9 0.5 O33 A:YM1402 4.9 31.9 0.5 CG A:GLU166 4.9 33.2 1.0

Fluorine binding site 6 out of 20 in the Structure of Sars-Cov-2 3CL Protease in Complex with Inhibitor 21C


Mono view


Stereo pair view

A full contact list of Fluorine with other atoms in the F binding site number 6 of Structure of Sars-Cov-2 3CL Protease in Complex with Inhibitor 21C within 5.0Å range: probe atom residue distance (Å) B Occ A:F402 b:45.4 occ:0.50 F24 A:YM1402 0.0 45.4 0.5 F24 A:YLV401 0.1 45.4 0.5 C23 A:YM1402 1.4 44.2 0.5 C23 A:YLV401 1.4 44.2 0.5 C22 A:YM1402 2.4 42.5 0.5 C22 A:YLV401 2.4 42.5 0.5 C25 A:YM1402 2.4 43.0 0.5 C25 A:YLV401 2.5 43.0 0.5 F26 A:YM1402 2.8 49.0 0.5 C21 A:YLV401 2.8 40.4 0.5 C21 A:YM1402 2.8 40.3 0.5 F26 A:YLV401 2.8 49.0 0.5 N A:THR190 2.9 27.4 1.0 C A:GLN189 3.0 34.9 1.0 CD A:GLN189 3.1 31.2 1.0 NE2 A:GLN189 3.1 38.4 1.0 CA A:GLN189 3.2 34.8 1.0 O20 A:YLV401 3.2 35.3 0.5 O20 A:YM1402 3.3 35.3 0.5 CG A:GLN189 3.3 34.4 1.0 O A:THR190 3.3 28.8 1.0 C A:THR190 3.5 29.7 1.0 CA A:THR190 3.6 30.9 1.0 OE1 A:GLN189 3.6 33.7 1.0 C31 A:YM1402 3.6 49.7 0.5 C27 A:YM1402 3.7 52.5 0.5 C31 A:YLV401 3.7 49.6 0.5 O A:GLN189 3.7 33.2 1.0 C27 A:YLV401 3.7 52.5 0.5 CB A:GLN189 3.8 36.1 1.0 C19 A:YLV401 4.1 36.4 0.5 C29 A:YM1402 4.1 51.3 0.5 C19 A:YM1402 4.1 36.4 0.5 C29 A:YLV401 4.2 51.3 0.5 N18 A:YLV401 4.2 28.4 0.5 O A:ARG188 4.2 27.3 1.0 N18 A:YM1402 4.3 28.5 0.5 N A:ALA191 4.3 34.1 1.0 N A:GLN189 4.4 28.7 1.0 O A:HOH548 4.6 30.1 1.0 F32 A:YM1402 4.8 47.9 0.5 C A:ARG188 4.8 32.2 1.0 F32 A:YLV401 4.8 47.8 0.5 F28 A:YM1402 4.8 61.9 0.5 F28 A:YLV401 4.8 61.9 0.5 CA A:ALA191 5.0 33.9 1.0

Fluorine binding site 7 out of 20 in the Structure of Sars-Cov-2 3CL Protease in Complex with Inhibitor 21C


Mono view


Stereo pair view

A full contact list of Fluorine with other atoms in the F binding site number 7 of Structure of Sars-Cov-2 3CL Protease in Complex with Inhibitor 21C within 5.0Å range: probe atom residue distance (Å) B Occ A:F402 b:49.0 occ:0.50 F26 A:YM1402 0.0 49.0 0.5 F26 A:YLV401 0.1 49.0 0.5 C25 A:YM1402 1.4 43.0 0.5 C25 A:YLV401 1.4 43.0 0.5 C23 A:YLV401 2.4 44.2 0.5 C27 A:YM1402 2.4 52.5 0.5 C23 A:YM1402 2.4 44.2 0.5 C27 A:YLV401 2.5 52.5 0.5 F24 A:YLV401 2.7 45.4 0.5 F28 A:YM1402 2.8 61.9 0.5 F24 A:YM1402 2.8 45.4 0.5 F28 A:YLV401 2.9 61.9 0.5 O A:HOH538 3.3 47.5 1.0 N A:ALA191 3.4 34.1 1.0 C A:THR190 3.4 29.7 1.0 CA A:THR190 3.4 30.9 1.0 O A:GLN189 3.6 33.2 1.0 C29 A:YM1402 3.7 51.3 0.5 C22 A:YM1402 3.7 42.5 0.5 C22 A:YLV401 3.7 42.5 0.5 N A:THR190 3.7 27.4 1.0 C29 A:YLV401 3.7 51.3 0.5 C A:GLN189 3.7 34.9 1.0 O A:HOH563 3.8 32.0 1.0 O A:THR190 4.1 28.8 1.0 C31 A:YM1402 4.1 49.7 0.5 C31 A:YLV401 4.2 49.6 0.5 CA A:ALA191 4.2 33.9 1.0 CG A:GLN189 4.2 34.4 1.0 NE2 A:GLN189 4.4 38.4 1.0 CB A:ALA191 4.5 31.3 1.0 CA A:GLN189 4.7 34.8 1.0 CD A:GLN189 4.7 31.2 1.0 F30 A:YM1402 4.8 50.5 0.5 F30 A:YLV401 4.8 50.5 0.5 CB A:THR190 4.9 35.6 1.0 C21 A:YLV401 4.9 40.4 0.5 C21 A:YM1402 4.9 40.3 0.5

Fluorine binding site 8 out of 20 in the Structure of Sars-Cov-2 3CL Protease in Complex with Inhibitor 21C


Mono view


Stereo pair view

A full contact list of Fluorine with other atoms in the F binding site number 8 of Structure of Sars-Cov-2 3CL Protease in Complex with Inhibitor 21C within 5.0Å range: probe atom residue distance (Å) B Occ A:F402 b:61.9 occ:0.50 F28 A:YM1402 0.0 61.9 0.5 F28 A:YLV401 0.1 61.9 0.5 C27 A:YLV401 1.4 52.5 0.5 C27 A:YM1402 1.4 52.5 0.5 C25 A:YLV401 2.3 43.0 0.5 C29 A:YM1402 2.4 51.3 0.5 C25 A:YM1402 2.4 43.0 0.5 C29 A:YLV401 2.4 51.3 0.5 F26 A:YLV401 2.7 49.0 0.5 F30 A:YM1402 2.8 50.5 0.5 F26 A:YM1402 2.8 49.0 0.5 F30 A:YLV401 2.8 50.5 0.5 C23 A:YLV401 3.6 44.2 0.5 CB A:ALA191 3.6 31.3 1.0 C31 A:YM1402 3.7 49.7 0.5 C23 A:YM1402 3.7 44.2 0.5 C31 A:YLV401 3.7 49.6 0.5 C22 A:YLV401 4.1 42.5 0.5 C22 A:YM1402 4.2 42.5 0.5 CA A:ALA191 4.2 33.9 1.0 N A:ALA191 4.2 34.1 1.0 O A:HOH563 4.6 32.0 1.0 F24 A:YLV401 4.7 45.4 0.5 F32 A:YM1402 4.8 47.9 0.5 F24 A:YM1402 4.8 45.4 0.5 F32 A:YLV401 4.8 47.8 0.5 C A:THR190 4.9 29.7 1.0

Fluorine binding site 9 out of 20 in the Structure of Sars-Cov-2 3CL Protease in Complex with Inhibitor 21C


Mono view


Stereo pair view

A full contact list of Fluorine with other atoms in the F binding site number 9 of Structure of Sars-Cov-2 3CL Protease in Complex with Inhibitor 21C within 5.0Å range: probe atom residue distance (Å) B Occ A:F402 b:50.5 occ:0.50 F30 A:YM1402 0.0 50.5 0.5 F30 A:YLV401 0.2 50.5 0.5 C29 A:YLV401 1.3 51.3 0.5 C29 A:YM1402 1.4 51.3 0.5 C27 A:YLV401 2.3 52.5 0.5 C27 A:YM1402 2.4 52.5 0.5 C31 A:YLV401 2.4 49.6 0.5 C31 A:YM1402 2.4 49.7 0.5 F28 A:YLV401 2.7 61.9 0.5 F28 A:YM1402 2.8 61.9 0.5 F32 A:YM1402 2.8 47.9 0.5 F32 A:YLV401 2.8 47.8 0.5 C25 A:YLV401 3.6 43.0 0.5 C22 A:YLV401 3.7 42.5 0.5 C25 A:YM1402 3.7 43.0 0.5 C22 A:YM1402 3.7 42.5 0.5 CG A:PRO168 3.7 37.7 1.0 CB A:PRO168 3.9 32.9 1.0 CA A:PRO168 3.9 33.3 1.0 C23 A:YLV401 4.1 44.2 0.5 C23 A:YM1402 4.2 44.2 0.5 N A:PRO168 4.3 31.8 1.0 CD A:PRO168 4.4 34.1 1.0 CB A:ALA191 4.5 31.3 1.0 F26 A:YLV401 4.7 49.0 0.5 F26 A:YM1402 4.8 49.0 0.5 CA A:ALA191 4.9 33.9 1.0 C21 A:YLV401 5.0 40.4 0.5 C21 A:YM1402 5.0 40.3 0.5

Fluorine binding site 10 out of 20 in the Structure of Sars-Cov-2 3CL Protease in Complex with Inhibitor 21C


Mono view


Stereo pair view

A full contact list of Fluorine with other atoms in the F binding site number 10 of Structure of Sars-Cov-2 3CL Protease in Complex with Inhibitor 21C within 5.0Å range: probe atom residue distance (Å) B Occ A:F402 b:47.9 occ:0.50 F32 A:YM1402 0.0 47.9 0.5 F32 A:YLV401 0.1 47.8 0.5 C31 A:YLV401 1.3 49.6 0.5 C31 A:YM1402 1.4 49.7 0.5 C29 A:YLV401 2.3 51.3 0.5 C22 A:YLV401 2.4 42.5 0.5 C29 A:YM1402 2.4 51.3 0.5 C22 A:YM1402 2.4 42.5 0.5 F30 A:YLV401 2.7 50.5 0.5 F30 A:YM1402 2.8 50.5 0.5 C21 A:YLV401 2.9 40.4 0.5 C21 A:YM1402 2.9 40.3 0.5 O A:GLU166 3.2 34.1 1.0 O20 A:YLV401 3.6 35.3 0.5 C27 A:YLV401 3.6 52.5 0.5 O20 A:YM1402 3.6 35.3 0.5 C23 A:YLV401 3.6 44.2 0.5 C23 A:YM1402 3.6 44.2 0.5 C27 A:YM1402 3.6 52.5 0.5 N A:PRO168 3.8 31.8 1.0 C A:LEU167 3.8 34.4 1.0 C A:GLU166 3.9 27.9 1.0 C25 A:YLV401 4.1 43.0 0.5 O A:HOH548 4.1 30.1 1.0 CA A:LEU167 4.1 21.3 1.0 C25 A:YM1402 4.1 43.0 0.5 CA A:PRO168 4.1 33.3 1.0 O A:LEU167 4.1 30.1 1.0 CD A:PRO168 4.2 34.1 1.0 N A:LEU167 4.3 21.0 1.0 CG A:PRO168 4.5 37.7 1.0 CB A:GLU166 4.6 29.0 1.0 C19 A:YLV401 4.7 36.4 0.5 F28 A:YLV401 4.7 61.9 0.5 F24 A:YLV401 4.7 45.4 0.5 C19 A:YM1402 4.7 36.4 0.5 F24 A:YM1402 4.8 45.4 0.5 F28 A:YM1402 4.8 61.9 0.5 O33 A:YLV401 4.8 31.9 0.5 CA A:GLU166 4.8 21.6 1.0 CB A:PRO168 4.9 32.9 1.0 O33 A:YM1402 4.9 31.9 0.5 CG A:GLU166 4.9 33.2 1.0

S.D.Chamandi, A.D.Rathnayake, J.Zhang, Y.Kim, K.D.Perera, A.R.M.Jesri, H.N.Nguyen, M.A.Baird, S.Makin, D.K.Meyerholz, M.M.Kashipathy, K.P.Battaile, S.Lovell, S.Perlman, K.O.Chang, W.C.Groutas. Structure of Sars-Cov-2 3CL Protease in Complex with Inhibitor 21C To Be Published.