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Fluorine in PDB 7m4t: Menin Bound to M-1121Protein crystallography data
The structure of Menin Bound to M-1121, PDB code: 7m4t
was solved by
J.Stuckey,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Other elements in 7m4t:
The structure of Menin Bound to M-1121 also contains other interesting chemical elements:
Fluorine Binding Sites:
The binding sites of Fluorine atom in the Menin Bound to M-1121
(pdb code 7m4t). This binding sites where shown within
5.0 Angstroms radius around Fluorine atom.
In total only one binding site of Fluorine was determined in the Menin Bound to M-1121, PDB code: 7m4t: Fluorine binding site 1 out of 1 in 7m4tGo back to Fluorine Binding Sites List in 7m4t
Fluorine binding site 1 out
of 1 in the Menin Bound to M-1121
Mono view Stereo pair view
Reference:
M.Zhang,
A.Aguilar,
S.Xu,
L.Huang,
K.Chinnaswamy,
T.Sleger,
B.Wang,
S.Gross,
B.N.Nicolay,
S.Ronseaux,
K.Harvey,
Y.Wang,
D.Mceachern,
P.D.Kirchhoff,
Z.Liu,
J.Stuckey,
A.E.Tron,
T.Liu,
S.Wang.
Discovery of M-1121 As An Orally Active Covalent Inhibitor of Menin-Mll Interaction Capable of Achieving Complete and Long-Lasting Tumor Regression. J.Med.Chem. V. 64 10333 2021.
Page generated: Fri Aug 2 09:17:56 2024
ISSN: ISSN 0022-2623 PubMed: 34196551 DOI: 10.1021/ACS.JMEDCHEM.1C00789 |
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