Fluorine in PDB 7ouh: Structure of the Stlv Intasome:B56 Complex Bound to the Strand- Transfer Inhibitor Bictegravir

Other elements in 7ouh:

The structure of Structure of the Stlv Intasome:B56 Complex Bound to the Strand- Transfer Inhibitor Bictegravir also contains other interesting chemical elements:

Zinc (Zn) 4 atoms
Magnesium (Mg) 4 atoms

Fluorine Binding Sites:

The binding sites of Fluorine atom in the Structure of the Stlv Intasome:B56 Complex Bound to the Strand- Transfer Inhibitor Bictegravir (pdb code 7ouh). This binding sites where shown within 5.0 Angstroms radius around Fluorine atom.
In total 6 binding sites of Fluorine where determined in the Structure of the Stlv Intasome:B56 Complex Bound to the Strand- Transfer Inhibitor Bictegravir, PDB code: 7ouh:
Jump to Fluorine binding site number: 1; 2; 3; 4; 5; 6;

Fluorine binding site 1 out of 6 in 7ouh

Go back to Fluorine Binding Sites List in 7ouh
Fluorine binding site 1 out of 6 in the Structure of the Stlv Intasome:B56 Complex Bound to the Strand- Transfer Inhibitor Bictegravir


Mono view


Stereo pair view

A full contact list of Fluorine with other atoms in the F binding site number 1 of Structure of the Stlv Intasome:B56 Complex Bound to the Strand- Transfer Inhibitor Bictegravir within 5.0Å range:
probe atom residue distance (Å) B Occ
E:F304

b:19.4
occ:1.00
FAE E:KLQ304 0.0 19.4 1.0
CAT E:KLQ304 1.4 19.4 1.0
CAI E:KLQ304 2.4 19.4 1.0
CAH E:KLQ304 2.4 19.4 1.0
N1 I:DG4 2.9 28.6 1.0
C6 I:DG4 3.1 28.6 1.0
C2 I:DG4 3.1 28.6 1.0
C5 I:DG4 3.3 28.6 1.0
CG2 E:THR152 3.5 34.7 1.0
N3 I:DG4 3.5 28.6 1.0
C4 I:DG4 3.5 28.6 1.0
CAV E:KLQ304 3.6 19.4 1.0
O6 I:DG4 3.6 28.6 1.0
CAU E:KLQ304 3.7 19.4 1.0
CA E:THR152 3.8 34.7 1.0
N2 I:DG4 3.8 28.6 1.0
CB E:THR152 4.1 34.7 1.0
CAY E:KLQ304 4.2 19.4 1.0
N7 I:DG4 4.2 28.6 1.0
N E:THR152 4.2 34.7 1.0
N9 I:DG4 4.4 28.6 1.0
O E:PRO151 4.5 23.1 1.0
C E:PRO151 4.5 23.1 1.0
N3 J:DC19 4.6 28.6 1.0
FAG E:KLQ304 4.7 19.4 1.0
C8 I:DG4 4.7 28.6 1.0
FAF E:KLQ304 4.8 19.4 1.0
N4 J:DC19 4.8 28.6 1.0
C4 J:DC19 5.0 28.6 1.0
C E:THR152 5.0 34.7 1.0

Fluorine binding site 2 out of 6 in 7ouh

Go back to Fluorine Binding Sites List in 7ouh
Fluorine binding site 2 out of 6 in the Structure of the Stlv Intasome:B56 Complex Bound to the Strand- Transfer Inhibitor Bictegravir


Mono view


Stereo pair view

A full contact list of Fluorine with other atoms in the F binding site number 2 of Structure of the Stlv Intasome:B56 Complex Bound to the Strand- Transfer Inhibitor Bictegravir within 5.0Å range:
probe atom residue distance (Å) B Occ
E:F304

b:19.4
occ:1.00
FAF E:KLQ304 0.0 19.4 1.0
CAU E:KLQ304 1.4 19.4 1.0
CAH E:KLQ304 2.4 19.4 1.0
CAY E:KLQ304 2.4 19.4 1.0
CAK E:KLQ304 2.9 19.4 1.0
OAA E:KLQ304 3.5 19.4 1.0
CAV E:KLQ304 3.6 19.4 1.0
CAT E:KLQ304 3.7 19.4 1.0
NAP E:KLQ304 4.0 19.4 1.0
CAI E:KLQ304 4.2 19.4 1.0
CAR E:KLQ304 4.2 19.4 1.0
CG E:PRO151 4.2 23.1 1.0
N4 J:DC19 4.3 28.6 1.0
C5 J:DC19 4.5 28.6 1.0
C4 J:DC19 4.5 28.6 1.0
FAG E:KLQ304 4.7 19.4 1.0
FAE E:KLQ304 4.8 19.4 1.0
CB E:PRO151 4.9 23.1 1.0

Fluorine binding site 3 out of 6 in 7ouh

Go back to Fluorine Binding Sites List in 7ouh
Fluorine binding site 3 out of 6 in the Structure of the Stlv Intasome:B56 Complex Bound to the Strand- Transfer Inhibitor Bictegravir


Mono view


Stereo pair view

A full contact list of Fluorine with other atoms in the F binding site number 3 of Structure of the Stlv Intasome:B56 Complex Bound to the Strand- Transfer Inhibitor Bictegravir within 5.0Å range:
probe atom residue distance (Å) B Occ
E:F304

b:19.4
occ:1.00
FAG E:KLQ304 0.0 19.4 1.0
CAV E:KLQ304 1.4 19.4 1.0
CAI E:KLQ304 2.3 19.4 1.0
CAY E:KLQ304 2.3 19.4 1.0
CAK E:KLQ304 2.8 19.4 1.0
NAP E:KLQ304 2.9 19.4 1.0
CB E:GLU158 3.2 18.9 1.0
C2' J:DC19 3.2 28.6 1.0
CG E:GLU158 3.3 18.9 1.0
N1 J:DC19 3.4 28.6 1.0
CAT E:KLQ304 3.6 19.4 1.0
CAU E:KLQ304 3.6 19.4 1.0
C2 J:DC19 3.6 28.6 1.0
OE1 E:GLU158 3.7 18.9 1.0
OAC E:KLQ304 3.7 19.4 1.0
CD E:GLU158 3.7 18.9 1.0
C1' J:DC19 3.7 28.6 1.0
C6 J:DC19 3.8 28.6 1.0
O2 J:DC19 4.0 28.6 1.0
CAH E:KLQ304 4.0 19.4 1.0
CAR E:KLQ304 4.1 19.4 1.0
N3 J:DC19 4.1 28.6 1.0
C5 J:DC19 4.3 28.6 1.0
C4 J:DC19 4.4 28.6 1.0
C3' J:DC19 4.5 28.6 1.0
CA E:GLU158 4.6 18.9 1.0
OE2 E:GLU158 4.7 18.9 1.0
CB E:PRO151 4.7 23.1 1.0
FAE E:KLQ304 4.7 19.4 1.0
CBA E:KLQ304 4.7 19.4 1.0
N2 I:DG4 4.7 28.6 1.0
FAF E:KLQ304 4.7 19.4 1.0
OAA E:KLQ304 4.7 19.4 1.0
MG E:MG303 4.8 20.7 1.0
CAX E:KLQ304 4.9 19.4 1.0
O E:PRO151 4.9 23.1 1.0

Fluorine binding site 4 out of 6 in 7ouh

Go back to Fluorine Binding Sites List in 7ouh
Fluorine binding site 4 out of 6 in the Structure of the Stlv Intasome:B56 Complex Bound to the Strand- Transfer Inhibitor Bictegravir


Mono view


Stereo pair view

A full contact list of Fluorine with other atoms in the F binding site number 4 of Structure of the Stlv Intasome:B56 Complex Bound to the Strand- Transfer Inhibitor Bictegravir within 5.0Å range:
probe atom residue distance (Å) B Occ
B:F304

b:20.5
occ:1.00
FAE B:KLQ304 0.0 20.5 1.0
CAT B:KLQ304 1.4 20.5 1.0
CAI B:KLQ304 2.4 20.5 1.0
CAH B:KLQ304 2.4 20.5 1.0
N1 K:DG4 2.9 28.6 1.0
C6 K:DG4 3.1 28.6 1.0
C2 K:DG4 3.1 28.6 1.0
C5 K:DG4 3.3 28.6 1.0
N3 K:DG4 3.5 28.6 1.0
C4 K:DG4 3.5 28.6 1.0
CG2 B:THR152 3.5 28.6 1.0
CAV B:KLQ304 3.6 20.5 1.0
O6 K:DG4 3.7 28.6 1.0
CAU B:KLQ304 3.7 20.5 1.0
CA B:THR152 3.8 28.6 1.0
N2 K:DG4 3.8 28.6 1.0
CB B:THR152 4.1 28.6 1.0
CAY B:KLQ304 4.2 20.5 1.0
N B:THR152 4.2 28.6 1.0
N7 K:DG4 4.2 28.6 1.0
N9 K:DG4 4.4 28.6 1.0
O B:PRO151 4.5 27.0 1.0
C B:PRO151 4.5 27.0 1.0
N3 L:DC19 4.6 28.6 1.0
FAG B:KLQ304 4.7 20.5 1.0
C8 K:DG4 4.7 28.6 1.0
FAF B:KLQ304 4.8 20.5 1.0
N4 L:DC19 4.8 28.6 1.0
C4 L:DC19 4.9 28.6 1.0
C B:THR152 5.0 28.6 1.0

Fluorine binding site 5 out of 6 in 7ouh

Go back to Fluorine Binding Sites List in 7ouh
Fluorine binding site 5 out of 6 in the Structure of the Stlv Intasome:B56 Complex Bound to the Strand- Transfer Inhibitor Bictegravir


Mono view


Stereo pair view

A full contact list of Fluorine with other atoms in the F binding site number 5 of Structure of the Stlv Intasome:B56 Complex Bound to the Strand- Transfer Inhibitor Bictegravir within 5.0Å range:
probe atom residue distance (Å) B Occ
B:F304

b:20.5
occ:1.00
FAF B:KLQ304 0.0 20.5 1.0
CAU B:KLQ304 1.4 20.5 1.0
CAH B:KLQ304 2.4 20.5 1.0
CAY B:KLQ304 2.4 20.5 1.0
CAK B:KLQ304 2.9 20.5 1.0
OAA B:KLQ304 3.5 20.5 1.0
CAV B:KLQ304 3.6 20.5 1.0
CAT B:KLQ304 3.7 20.5 1.0
NAP B:KLQ304 4.0 20.5 1.0
CAI B:KLQ304 4.2 20.5 1.0
CAR B:KLQ304 4.2 20.5 1.0
CG B:PRO151 4.2 27.0 1.0
N4 L:DC19 4.3 28.6 1.0
C5 L:DC19 4.5 28.6 1.0
C4 L:DC19 4.5 28.6 1.0
FAG B:KLQ304 4.7 20.5 1.0
FAE B:KLQ304 4.8 20.5 1.0
CB B:PRO151 4.9 27.0 1.0

Fluorine binding site 6 out of 6 in 7ouh

Go back to Fluorine Binding Sites List in 7ouh
Fluorine binding site 6 out of 6 in the Structure of the Stlv Intasome:B56 Complex Bound to the Strand- Transfer Inhibitor Bictegravir


Mono view


Stereo pair view

A full contact list of Fluorine with other atoms in the F binding site number 6 of Structure of the Stlv Intasome:B56 Complex Bound to the Strand- Transfer Inhibitor Bictegravir within 5.0Å range:
probe atom residue distance (Å) B Occ
B:F304

b:20.5
occ:1.00
FAG B:KLQ304 0.0 20.5 1.0
CAV B:KLQ304 1.4 20.5 1.0
CAI B:KLQ304 2.3 20.5 1.0
CAY B:KLQ304 2.3 20.5 1.0
CAK B:KLQ304 2.8 20.5 1.0
NAP B:KLQ304 2.9 20.5 1.0
CB B:GLU158 3.2 21.2 1.0
C2' L:DC19 3.2 28.6 1.0
CG B:GLU158 3.3 21.2 1.0
N1 L:DC19 3.4 28.6 1.0
CAT B:KLQ304 3.6 20.5 1.0
CAU B:KLQ304 3.6 20.5 1.0
C2 L:DC19 3.6 28.6 1.0
OE1 B:GLU158 3.7 21.2 1.0
OAC B:KLQ304 3.7 20.5 1.0
CD B:GLU158 3.7 21.2 1.0
C1' L:DC19 3.7 28.6 1.0
C6 L:DC19 3.8 28.6 1.0
O2 L:DC19 4.0 28.6 1.0
CAH B:KLQ304 4.0 20.5 1.0
CAR B:KLQ304 4.1 20.5 1.0
N3 L:DC19 4.1 28.6 1.0
C5 L:DC19 4.3 28.6 1.0
C4 L:DC19 4.4 28.6 1.0
C3' L:DC19 4.5 28.6 1.0
CA B:GLU158 4.6 21.2 1.0
OE2 B:GLU158 4.6 21.2 1.0
CB B:PRO151 4.7 27.0 1.0
FAE B:KLQ304 4.7 20.5 1.0
CBA B:KLQ304 4.7 20.5 1.0
FAF B:KLQ304 4.7 20.5 1.0
N2 K:DG4 4.7 28.6 1.0
OAA B:KLQ304 4.8 20.5 1.0
MG B:MG303 4.8 19.6 1.0
CAX B:KLQ304 4.9 20.5 1.0
O B:PRO151 4.9 27.0 1.0

Reference:

M.S.Barski, T.Vanzo, X.Zhao, S.J.Smith, A.Ballandras-Colas, N.B.Cronin, V.E.Pye, S.H.Hughes, T.R.Burke, P.Cherepanov, G.N.Maertens. Structural Basis For the Inhibition of Htlv-1 Integration Inferred From Cryo-Em Deltaretroviral Intasome Structures Nat Commun 2021.
ISSN: ESSN 2041-1723
Page generated: Sat Aug 21 13:53:29 2021

Last articles

Zn in 7VD8
Zn in 7V1R
Zn in 7V1Q
Zn in 7VPF
Zn in 7T85
Zn in 7T5F
Zn in 7NF9
Zn in 7M4M
Zn in 7M4O
Zn in 7M4N
© Copyright 2008-2020 by atomistry.com
Home   |    Site Map   |    Copyright   |    Contact us   |    Privacy