Fluorine in PDB 7r9f: Wild-Type Yeast Pseudouridine Synthase, PUS1, Bound to 5-Fluorouracil Rna

The structure of Wild-Type Yeast Pseudouridine Synthase, PUS1, Bound to 5-Fluorouracil Rna, PDB code: 7r9f was solved by L.A.Doyle, B.L.Stoddard, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	46.88 / 2.89
Space group	P 61 2 2
Cell size a, b, c (Å), α, β, γ (°)	134.466, 134.466, 158.13, 90, 90, 120
R / Rfree (%)	25.1 / 29

The binding sites of Fluorine atom in the Wild-Type Yeast Pseudouridine Synthase, PUS1, Bound to 5-Fluorouracil Rna (pdb code 7r9f). This binding sites where shown within 5.0 Angstroms radius around Fluorine atom.
In total only one binding site of Fluorine was determined in the Wild-Type Yeast Pseudouridine Synthase, PUS1, Bound to 5-Fluorouracil Rna, PDB code: 7r9f:

Fluorine binding site 1 out of 1 in the Wild-Type Yeast Pseudouridine Synthase, PUS1, Bound to 5-Fluorouracil Rna


Mono view


Stereo pair view

A full contact list of Fluorine with other atoms in the F binding site number 1 of Wild-Type Yeast Pseudouridine Synthase, PUS1, Bound to 5-Fluorouracil Rna within 5.0Å range: probe atom residue distance (Å) B Occ B:F1 b:82.6 occ:0.98 F5 B:5UD1 0.0 82.6 1.0 C5 B:5UD1 1.4 84.4 1.0 C4 B:5UD1 2.5 85.3 1.0 C6 B:5UD1 2.5 64.1 1.0 O4 B:5UD1 2.7 85.9 1.0 C4 B:A2 3.4 67.0 1.0 N9 B:A2 3.7 58.4 1.0 C5 B:A2 3.7 68.3 1.0 N3 B:A2 3.7 67.9 1.0 N3 B:5UD1 3.8 73.8 1.0 OD1 A:ASN94 3.8 94.6 1.0 N1 B:5UD1 3.8 67.2 1.0 ND2 A:ASN94 3.9 81.7 1.0 C8 B:A2 4.0 67.5 1.0 C2 B:A2 4.1 65.8 1.0 N7 B:A2 4.1 66.4 1.0 C6 B:A2 4.2 68.0 1.0 CG A:ASN94 4.2 76.4 1.0 C1' B:A2 4.2 61.4 1.0 C2 B:5UD1 4.3 64.8 1.0 N1 B:A2 4.3 71.7 1.0 NE2 A:GLN92 4.5 97.5 1.0 O4' B:A2 4.8 71.9 1.0 N6 B:A2 5.0 52.0 1.0

L.A.Doyle, B.L.Stoddard. Wild-Type Yeast Pseudouridine Synthase Bound to 5-Fluorouracil Rna To Be Published.