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Fluorine in PDB 7r9v: Structure of PIK3CA with Covalent Inhibitor 19Enzymatic activity of Structure of PIK3CA with Covalent Inhibitor 19
All present enzymatic activity of Structure of PIK3CA with Covalent Inhibitor 19:
2.7.1.153; 2.7.11.1; Protein crystallography data
The structure of Structure of PIK3CA with Covalent Inhibitor 19, PDB code: 7r9v
was solved by
J.E.Burke,
J.A.Mcphail,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Fluorine Binding Sites:
The binding sites of Fluorine atom in the Structure of PIK3CA with Covalent Inhibitor 19
(pdb code 7r9v). This binding sites where shown within
5.0 Angstroms radius around Fluorine atom.
In total 2 binding sites of Fluorine where determined in the Structure of PIK3CA with Covalent Inhibitor 19, PDB code: 7r9v: Jump to Fluorine binding site number: 1; 2; Fluorine binding site 1 out of 2 in 7r9vGo back to Fluorine Binding Sites List in 7r9v
Fluorine binding site 1 out
of 2 in the Structure of PIK3CA with Covalent Inhibitor 19
Mono view Stereo pair view
Fluorine binding site 2 out of 2 in 7r9vGo back to Fluorine Binding Sites List in 7r9v
Fluorine binding site 2 out
of 2 in the Structure of PIK3CA with Covalent Inhibitor 19
Mono view Stereo pair view
Reference:
C.Borsari,
E.Keles,
J.A.Mcphail,
A.Schaefer,
R.Sriramaratnam,
W.Goch,
T.Schaefer,
M.De Pascale,
W.Bal,
M.Gstaiger,
J.E.Burke,
M.P.Wymann.
Covalent Proximity Scanning of A Distal Cysteine to Target PI3K Alpha. J.Am.Chem.Soc. V. 144 6326 2022.
Page generated: Wed Apr 5 00:53:33 2023
ISSN: ESSN 1520-5126 PubMed: 35353516 DOI: 10.1021/JACS.1C13568 |
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