Fluorine in PDB 7trq: Human M4 Muscarinic Acetylcholine Receptor Complex with GI1 and the Agonist Iperoxo and Positive Allosteric Modulator VU0467154

The binding sites of Fluorine atom in the Human M4 Muscarinic Acetylcholine Receptor Complex with GI1 and the Agonist Iperoxo and Positive Allosteric Modulator VU0467154 (pdb code 7trq). This binding sites where shown within 5.0 Angstroms radius around Fluorine atom.
In total 3 binding sites of Fluorine where determined in the Human M4 Muscarinic Acetylcholine Receptor Complex with GI1 and the Agonist Iperoxo and Positive Allosteric Modulator VU0467154, PDB code: 7trq:
Jump to Fluorine binding site number: 1; 2; 3;

Fluorine binding site 1 out of 3 in the Human M4 Muscarinic Acetylcholine Receptor Complex with GI1 and the Agonist Iperoxo and Positive Allosteric Modulator VU0467154


Mono view


Stereo pair view

A full contact list of Fluorine with other atoms in the F binding site number 1 of Human M4 Muscarinic Acetylcholine Receptor Complex with GI1 and the Agonist Iperoxo and Positive Allosteric Modulator VU0467154 within 5.0Å range: probe atom residue distance (Å) B Occ R:F602 b:147.6 occ:1.00 F R:IUI602 0.0 147.6 1.0 C15 R:IUI602 1.3 147.6 1.0 F1 R:IUI602 2.1 147.6 1.0 F2 R:IUI602 2.1 147.6 1.0 S1 R:IUI602 2.6 147.6 1.0 O2 R:IUI602 2.7 147.6 1.0 O1 R:IUI602 3.5 147.6 1.0 C12 R:IUI602 3.8 147.6 1.0 O R:ILE93 4.2 144.4 1.0 C11 R:IUI602 4.4 147.6 1.0 C13 R:IUI602 4.6 147.6 1.0

Fluorine binding site 2 out of 3 in the Human M4 Muscarinic Acetylcholine Receptor Complex with GI1 and the Agonist Iperoxo and Positive Allosteric Modulator VU0467154


Mono view


Stereo pair view

A full contact list of Fluorine with other atoms in the F binding site number 2 of Human M4 Muscarinic Acetylcholine Receptor Complex with GI1 and the Agonist Iperoxo and Positive Allosteric Modulator VU0467154 within 5.0Å range: probe atom residue distance (Å) B Occ R:F602 b:147.6 occ:1.00 F1 R:IUI602 0.0 147.6 1.0 C15 R:IUI602 1.3 147.6 1.0 F R:IUI602 2.1 147.6 1.0 F2 R:IUI602 2.1 147.6 1.0 S1 R:IUI602 2.6 147.6 1.0 O1 R:IUI602 2.7 147.6 1.0 O2 R:IUI602 3.5 147.6 1.0 C12 R:IUI602 3.8 147.6 1.0 C13 R:IUI602 4.1 147.6 1.0 O R:ILE93 4.5 144.4 1.0 CB R:ILE93 4.6 144.4 1.0 CD1 R:ILE93 4.7 144.4 1.0 C11 R:IUI602 5.0 147.6 1.0

Fluorine binding site 3 out of 3 in the Human M4 Muscarinic Acetylcholine Receptor Complex with GI1 and the Agonist Iperoxo and Positive Allosteric Modulator VU0467154


Mono view


Stereo pair view

A full contact list of Fluorine with other atoms in the F binding site number 3 of Human M4 Muscarinic Acetylcholine Receptor Complex with GI1 and the Agonist Iperoxo and Positive Allosteric Modulator VU0467154 within 5.0Å range: probe atom residue distance (Å) B Occ R:F602 b:147.6 occ:1.00 F2 R:IUI602 0.0 147.6 1.0 C15 R:IUI602 1.3 147.6 1.0 F1 R:IUI602 2.1 147.6 1.0 F R:IUI602 2.1 147.6 1.0 S1 R:IUI602 2.6 147.6 1.0 O R:ILE93 2.7 144.4 1.0 C12 R:IUI602 2.9 147.6 1.0 C13 R:IUI602 3.1 147.6 1.0 C R:ILE93 3.4 144.4 1.0 O2 R:IUI602 3.5 147.6 1.0 O1 R:IUI602 3.5 147.6 1.0 CB R:ILE93 3.5 144.4 1.0 CA R:ILE93 3.6 144.4 1.0 C11 R:IUI602 3.7 147.6 1.0 C14 R:IUI602 4.1 147.6 1.0 CG2 R:ILE93 4.4 144.4 1.0 CD1 R:ILE93 4.5 144.4 1.0 C10 R:IUI602 4.6 147.6 1.0 N R:ILE94 4.6 145.6 1.0 CG1 R:ILE93 4.6 144.4 1.0 C9 R:IUI602 4.8 147.6 1.0

D.M.Thal, Z.Vuckovic, J.I.Mobbs, M.J.Belousoff, A.Glukhova, P.M.Sexton, R.Danev, D.M.Thal. N/A N/A.
ISSN: ESSN 2050-084X