Atomistry » Fluorine » PDB 7tsd-7u8s » 7u5w
Atomistry »
  Fluorine »
    PDB 7tsd-7u8s »
      7u5w »

Fluorine in PDB 7u5w: Crystal Structure Analysis of Human Carbonic Anhydrase 2

Enzymatic activity of Crystal Structure Analysis of Human Carbonic Anhydrase 2

All present enzymatic activity of Crystal Structure Analysis of Human Carbonic Anhydrase 2:
4.2.1.1;

Protein crystallography data

The structure of Crystal Structure Analysis of Human Carbonic Anhydrase 2, PDB code: 7u5w was solved by H.-S.Seo, S.Dhe-Paganon, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å) 36.61 / 1.13
Space group P 21 21 21
Cell size a, b, c (Å), α, β, γ (°) 42.16, 71.46, 73.82, 90, 90, 90
R / Rfree (%) 15.7 / 18

Other elements in 7u5w:

The structure of Crystal Structure Analysis of Human Carbonic Anhydrase 2 also contains other interesting chemical elements:

Zinc (Zn) 1 atom

Fluorine Binding Sites:

Pages:

>>> Page 1 <<< Page 2, Binding sites: 11 - 12;

Binding sites:

The binding sites of Fluorine atom in the Crystal Structure Analysis of Human Carbonic Anhydrase 2 (pdb code 7u5w). This binding sites where shown within 5.0 Angstroms radius around Fluorine atom.
In total 12 binding sites of Fluorine where determined in the Crystal Structure Analysis of Human Carbonic Anhydrase 2, PDB code: 7u5w:
Jump to Fluorine binding site number: 1; 2; 3; 4; 5; 6; 7; 8; 9; 10;

Fluorine binding site 1 out of 12 in 7u5w

Go back to Fluorine Binding Sites List in 7u5w
Fluorine binding site 1 out of 12 in the Crystal Structure Analysis of Human Carbonic Anhydrase 2


Mono view


Stereo pair view

A full contact list of Fluorine with other atoms in the F binding site number 1 of Crystal Structure Analysis of Human Carbonic Anhydrase 2 within 5.0Å range:
probe atom residue distance (Å) B Occ
A:F20

b:26.0
occ:1.00
 F A:PFF20 0.0 26.0 1.0
CZ A:PFF20 1.4 20.1 1.0
CE2 A:PFF20 2.4 18.0 1.0
CE1 A:PFF20 2.4 19.2 1.0
O A:HOH514 3.6 40.6 1.0
CD2 A:PFF20 3.6 16.1 1.0
CD1 A:PFF20 3.7 17.9 1.0
CD1 A:TRP5 4.1 17.5 1.0
CB A:PRO200 4.2 12.8 1.0
CG A:PFF20 4.2 15.5 1.0
NE1 A:TRP5 4.6 18.0 1.0
CB A:ASP19 4.8 18.2 1.0
O A:HOH593 4.9 41.2 1.0
OD1 A:ASP19 4.9 24.8 1.0

Fluorine binding site 2 out of 12 in 7u5w

Go back to Fluorine Binding Sites List in 7u5w
Fluorine binding site 2 out of 12 in the Crystal Structure Analysis of Human Carbonic Anhydrase 2


Mono view


Stereo pair view

A full contact list of Fluorine with other atoms in the F binding site number 2 of Crystal Structure Analysis of Human Carbonic Anhydrase 2 within 5.0Å range:
probe atom residue distance (Å) B Occ
A:F66

b:20.9
occ:1.00
 F A:PFF66 0.0 20.9 1.0
CZ A:PFF66 1.3 15.1 1.0
CE2 A:PFF66 2.4 14.8 1.0
CE1 A:PFF66 2.4 15.7 1.0
CD1 A:PFF95 3.1 11.2 1.0
CE1 A:PFF95 3.1 12.1 1.0
CE1 A:PFF225 3.3 17.3 1.0
CG1 A:VAL159 3.4 14.6 1.0
CZ A:PFF225 3.4 16.4 1.0
F A:PFF225 3.6 20.0 1.0
CD2 A:PFF66 3.6 13.4 1.0
CD1 A:PFF66 3.6 13.8 1.0
CD1 A:PFF225 3.9 14.9 1.0
CZ A:PFF95 4.0 12.8 1.0
CG A:PFF95 4.0 9.6 1.0
CG A:PFF66 4.1 13.2 1.0
CE2 A:PFF225 4.1 16.8 1.0
CD1 A:LEU163 4.3 13.4 1.0
CD2 A:LEU163 4.5 12.6 1.0
CG A:PFF225 4.5 11.3 1.0
O A:HOH416 4.6 13.5 1.0
F A:PFF95 4.6 19.7 1.0
CD2 A:PFF225 4.6 15.4 1.0
CB A:VAL159 4.6 13.0 1.0
CD2 A:PFF95 4.7 10.5 1.0
CE2 A:PFF95 4.7 12.0 1.0
CB A:PFF95 4.7 10.2 1.0
CD1 A:LEU156 4.8 13.6 1.0
CG A:LEU163 4.9 12.9 1.0

Fluorine binding site 3 out of 12 in 7u5w

Go back to Fluorine Binding Sites List in 7u5w
Fluorine binding site 3 out of 12 in the Crystal Structure Analysis of Human Carbonic Anhydrase 2


Mono view


Stereo pair view

A full contact list of Fluorine with other atoms in the F binding site number 3 of Crystal Structure Analysis of Human Carbonic Anhydrase 2 within 5.0Å range:
probe atom residue distance (Å) B Occ
A:F70

b:18.0
occ:1.00
 F A:PFF70 0.0 18.0 1.0
CZ A:PFF70 1.3 13.8 1.0
CE1 A:PFF70 2.3 12.3 1.0
CE2 A:PFF70 2.3 13.5 1.0
CE2 A:PFF93 3.2 11.4 1.0
CD1 A:PFF178 3.4 13.7 1.0
CB A:PRO180 3.4 13.8 1.0
CG A:PRO180 3.4 13.8 1.0
CD A:PRO180 3.5 13.9 1.0
CD1 A:PFF70 3.6 12.8 1.0
CD2 A:PFF70 3.6 12.8 1.0
CD2 A:PFF93 3.7 11.1 1.0
CE1 A:PFF178 3.9 14.5 1.0
CG A:PFF70 4.1 12.9 1.0
CG1 A:VAL68 4.1 13.3 1.0
N A:PRO180 4.1 13.0 1.0
O A:PFF178 4.2 16.4 1.0
CB A:SER56 4.2 13.3 1.0
CA A:PRO180 4.3 13.3 1.0
CZ A:PFF93 4.3 11.9 1.0
CG A:PFF178 4.5 13.8 1.0
F A:PFF93 4.6 17.5 1.0
CD2 A:LEU90 4.6 13.7 1.0
CB A:PFF178 4.8 15.6 1.0
C A:PFF178 4.8 14.6 1.0
CB A:VAL68 5.0 12.1 1.0

Fluorine binding site 4 out of 12 in 7u5w

Go back to Fluorine Binding Sites List in 7u5w
Fluorine binding site 4 out of 12 in the Crystal Structure Analysis of Human Carbonic Anhydrase 2


Mono view


Stereo pair view

A full contact list of Fluorine with other atoms in the F binding site number 4 of Crystal Structure Analysis of Human Carbonic Anhydrase 2 within 5.0Å range:
probe atom residue distance (Å) B Occ
A:F93

b:17.5
occ:1.00
 F A:PFF93 0.0 17.5 1.0
CZ A:PFF93 1.3 11.9 1.0
CE1 A:PFF93 2.3 10.7 1.0
CE2 A:PFF93 2.4 11.4 1.0
CE1 A:PFF178 3.0 14.5 1.0
CG2 A:VAL159 3.3 15.6 1.0
CG2 A:VAL68 3.4 12.9 1.0
CZ A:PFF178 3.4 15.3 1.0
CD1 A:PFF178 3.4 13.7 1.0
CD1 A:PFF93 3.6 10.3 1.0
CD2 A:PFF93 3.6 11.1 1.0
F A:PFF178 3.8 22.1 1.0
CB A:VAL68 3.8 12.1 1.0
CD1 A:LEU183 4.0 16.1 1.0
CG1 A:VAL68 4.1 13.3 1.0
CG A:PFF93 4.1 9.8 1.0
CE1 A:PFF175 4.2 13.7 1.0
CG A:PFF178 4.2 13.8 1.0
CE2 A:PFF178 4.3 15.6 1.0
CD2 A:PFF178 4.6 13.8 1.0
F A:PFF70 4.6 18.0 1.0
CB A:VAL159 4.6 13.0 1.0
F A:PFF175 4.7 22.4 1.0
CG1 A:VAL159 4.7 14.6 1.0
F A:PFF95 4.9 19.7 1.0
CZ A:PFF175 4.9 16.3 1.0

Fluorine binding site 5 out of 12 in 7u5w

Go back to Fluorine Binding Sites List in 7u5w
Fluorine binding site 5 out of 12 in the Crystal Structure Analysis of Human Carbonic Anhydrase 2


Mono view


Stereo pair view

A full contact list of Fluorine with other atoms in the F binding site number 5 of Crystal Structure Analysis of Human Carbonic Anhydrase 2 within 5.0Å range:
probe atom residue distance (Å) B Occ
A:F95

b:19.7
occ:1.00
 F A:PFF95 0.0 19.7 1.0
CZ A:PFF95 1.3 12.8 1.0
CE1 A:PFF95 2.3 12.1 1.0
CE2 A:PFF95 2.4 12.0 1.0
CD1 A:LEU156 3.1 13.6 1.0
CD1 A:LEU183 3.6 16.1 1.0
CD1 A:PFF95 3.6 11.2 1.0
CD2 A:LEU183 3.6 17.1 1.0
CD2 A:PFF95 3.6 10.5 1.0
CE1 A:PFF93 3.9 10.7 1.0
CD1 A:LEU118 4.0 9.4 1.0
F A:PFF225 4.1 20.0 1.0
CG A:PFF95 4.1 9.6 1.0
CG A:LEU183 4.2 14.9 1.0
CD1 A:PFF93 4.4 10.3 1.0
CD2 A:LEU118 4.4 10.8 1.0
CG A:LEU156 4.6 12.6 1.0
F A:PFF66 4.6 20.9 1.0
CG A:LEU118 4.7 9.6 1.0
CZ A:PFF93 4.7 11.9 1.0
F A:PFF93 4.9 17.5 1.0
CG1 A:VAL159 4.9 14.6 1.0
CB A:LEU183 4.9 13.6 1.0
CG2 A:VAL159 4.9 15.6 1.0
CB A:LEU118 5.0 9.1 1.0

Fluorine binding site 6 out of 12 in 7u5w

Go back to Fluorine Binding Sites List in 7u5w
Fluorine binding site 6 out of 12 in the Crystal Structure Analysis of Human Carbonic Anhydrase 2


Mono view


Stereo pair view

A full contact list of Fluorine with other atoms in the F binding site number 6 of Crystal Structure Analysis of Human Carbonic Anhydrase 2 within 5.0Å range:
probe atom residue distance (Å) B Occ
A:F130

b:25.0
occ:1.00
 F A:PFF130 0.0 25.0 1.0
CZ A:PFF130 1.3 19.1 1.0
CE2 A:PFF130 2.3 15.6 1.0
CE1 A:PFF130 2.4 17.6 1.0
O A:HOH734 3.2 35.9 1.0
O A:HOH604 3.6 30.8 1.0
CD2 A:PFF130 3.6 15.3 1.0
CD1 A:PFF130 3.6 15.9 1.0
CG1 A:VAL134 3.8 15.7 1.0
O A:HOH758 3.9 44.1 1.0
CD1 A:LEU140 4.1 11.6 1.0
CG A:PFF130 4.1 15.7 1.0
CD2 A:LEU197 4.6 13.3 1.0
CG1 A:VAL121 4.7 11.0 1.0
O A:HOH638 5.0 33.0 1.0

Fluorine binding site 7 out of 12 in 7u5w

Go back to Fluorine Binding Sites List in 7u5w
Fluorine binding site 7 out of 12 in the Crystal Structure Analysis of Human Carbonic Anhydrase 2


Mono view


Stereo pair view

A full contact list of Fluorine with other atoms in the F binding site number 7 of Crystal Structure Analysis of Human Carbonic Anhydrase 2 within 5.0Å range:
probe atom residue distance (Å) B Occ
A:F146

b:15.5
occ:1.00
 F A:PFF146 0.0 15.5 1.0
CZ A:PFF146 1.3 10.9 1.0
CE1 A:PFF146 2.3 11.5 1.0
CE2 A:PFF146 2.4 10.6 1.0
CB A:HIS107 3.1 8.8 1.0
CG2 A:VAL109 3.4 12.8 1.0
C A:HIS107 3.5 8.7 1.0
CD1 A:PFF146 3.6 10.2 1.0
CD2 A:PFF146 3.6 10.2 1.0
N A:THR108 3.7 9.3 1.0
O A:HIS107 3.7 9.7 1.0
CG1 A:VAL210 3.7 11.8 1.0
CD1 A:ILE33 3.8 14.2 1.0
O A:THR108 3.8 10.6 1.0
C A:THR108 3.8 9.2 1.0
CA A:HIS107 3.9 8.5 1.0
CA A:THR108 4.0 10.2 1.0
CG A:PFF146 4.1 10.2 1.0
CG A:HIS107 4.3 8.5 1.0
N A:VAL109 4.4 10.5 1.0
CB A:VAL109 4.7 12.3 1.0
CG1 A:ILE33 4.8 13.0 1.0
N A:HIS107 4.8 8.2 1.0
CA A:VAL109 4.9 11.2 1.0
OE1 A:GLU117 5.0 9.3 1.0

Fluorine binding site 8 out of 12 in 7u5w

Go back to Fluorine Binding Sites List in 7u5w
Fluorine binding site 8 out of 12 in the Crystal Structure Analysis of Human Carbonic Anhydrase 2


Mono view


Stereo pair view

A full contact list of Fluorine with other atoms in the F binding site number 8 of Crystal Structure Analysis of Human Carbonic Anhydrase 2 within 5.0Å range:
probe atom residue distance (Å) B Occ
A:F175

b:22.4
occ:1.00
 F A:PFF175 0.0 22.4 1.0
CZ A:PFF175 1.3 16.3 1.0
CE1 A:PFF175 2.3 13.7 1.0
CE2 A:PFF175 2.4 17.4 1.0
N A:VAL159 2.9 13.0 1.0
CG2 A:VAL159 3.0 15.6 1.0
C A:LYS158 3.1 13.8 1.0
CA A:VAL159 3.1 12.2 1.0
CG A:LYS158 3.4 21.5 1.0
CB A:LYS158 3.4 18.3 1.0
O A:LYS158 3.4 15.4 1.0
CD2 A:PFF178 3.4 13.8 1.0
CD1 A:PFF175 3.6 12.4 1.0
CD A:LYS158 3.6 24.3 1.0
CD2 A:PFF175 3.6 15.6 1.0
CB A:VAL159 3.6 13.0 1.0
CE2 A:PFF178 3.7 15.6 1.0
CA A:LYS158 3.9 15.7 1.0
CE A:LYS158 4.1 26.0 1.0
CG A:PFF175 4.1 12.8 1.0
CG A:PFF178 4.1 13.8 1.0
CZ A:PFF178 4.5 15.3 1.0
C A:VAL159 4.5 12.7 1.0
CG1 A:VAL159 4.5 14.6 1.0
CB A:PFF178 4.6 15.6 1.0
F A:PFF93 4.7 17.5 1.0
N A:LYS158 4.7 13.6 1.0
CD1 A:PFF178 4.8 13.7 1.0
CG1 A:VAL162 5.0 14.1 1.0
O A:VAL159 5.0 13.5 1.0

Fluorine binding site 9 out of 12 in 7u5w

Go back to Fluorine Binding Sites List in 7u5w
Fluorine binding site 9 out of 12 in the Crystal Structure Analysis of Human Carbonic Anhydrase 2


Mono view


Stereo pair view

A full contact list of Fluorine with other atoms in the F binding site number 9 of Crystal Structure Analysis of Human Carbonic Anhydrase 2 within 5.0Å range:
probe atom residue distance (Å) B Occ
A:F178

b:22.1
occ:1.00
 F A:PFF178 0.0 22.1 1.0
CZ A:PFF178 1.3 15.3 1.0
CE2 A:PFF178 2.4 15.6 1.0
CE1 A:PFF178 2.4 14.5 1.0
O A:GLY155 2.7 19.4 1.0
CG A:LEU183 3.1 14.9 1.0
CD2 A:LEU183 3.2 17.1 1.0
CD1 A:LEU183 3.3 16.1 1.0
O A:HOH455 3.5 22.0 1.0
CD2 A:PFF178 3.6 13.8 1.0
CD1 A:PFF178 3.6 13.7 1.0
C A:GLY155 3.7 15.3 1.0
F A:PFF93 3.8 17.5 1.0
CG2 A:VAL159 3.8 15.6 1.0
CG A:PFF178 4.1 13.8 1.0
O A:ASP179 4.2 14.0 1.0
CA A:LEU156 4.4 13.6 1.0
N A:LEU156 4.4 12.4 1.0
CZ A:PFF93 4.5 11.9 1.0
CB A:LEU183 4.6 13.6 1.0
CA A:PRO180 4.7 13.3 1.0
CA A:GLY155 4.7 16.4 1.0
C A:ASP179 4.8 14.8 1.0
N A:LEU183 4.9 12.2 1.0
C A:GLY182 5.0 13.1 1.0

Fluorine binding site 10 out of 12 in 7u5w

Go back to Fluorine Binding Sites List in 7u5w
Fluorine binding site 10 out of 12 in the Crystal Structure Analysis of Human Carbonic Anhydrase 2


Mono view


Stereo pair view

A full contact list of Fluorine with other atoms in the F binding site number 10 of Crystal Structure Analysis of Human Carbonic Anhydrase 2 within 5.0Å range:
probe atom residue distance (Å) B Occ
A:F225

b:20.0
occ:1.00
 F A:PFF225 0.0 20.0 1.0
CZ A:PFF225 1.3 16.4 1.0
CE1 A:PFF225 2.3 17.3 1.0
CE2 A:PFF225 2.4 16.8 1.0
CE2 A:PFF95 3.3 12.0 1.0
CD2 A:LEU156 3.5 13.6 1.0
CZ A:PFF95 3.5 12.8 1.0
CD1 A:LEU156 3.5 13.6 1.0
CD1 A:PFF225 3.5 14.9 1.0
CD2 A:PFF95 3.6 10.5 1.0
CD2 A:PFF225 3.6 15.4 1.0
F A:PFF66 3.6 20.9 1.0
CD2 A:LEU147 3.7 11.8 1.0
CE1 A:PFF95 3.9 12.1 1.0
CG A:PFF95 4.0 9.6 1.0
CG A:LEU156 4.0 12.6 1.0
F A:PFF95 4.1 19.7 1.0
CG A:PFF225 4.1 11.3 1.0
CD1 A:PFF95 4.2 11.2 1.0
CZ A:PFF66 4.9 15.1 1.0
CB A:PFF95 4.9 10.2 1.0
CG2 A:VAL160 5.0 21.4 1.0

Reference:

H.-S.Seo, S.Dhe-Paganon. Crystal Structure Analysis of Human Carbonic Anhydrase 2 To Be Published.
Page generated: Wed Jul 16 00:49:44 2025

Last articles

Fe in 2YXO
Fe in 2YRS
Fe in 2YXC
Fe in 2YNM
Fe in 2YVJ
Fe in 2YP1
Fe in 2YU2
Fe in 2YU1
Fe in 2YQB
Fe in 2YOO
© Copyright 2008-2020 by atomistry.com
Home   |    Site Map   |    Copyright   |    Contact us   |    Privacy