Fluorine in PDB 7u8s: Crystal Structure of Kpc-2 with Compound 2

All present enzymatic activity of Crystal Structure of Kpc-2 with Compound 2:
3.5.2.6;

The structure of Crystal Structure of Kpc-2 with Compound 2, PDB code: 7u8s was solved by A.Akhtar, Y.Chen, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	47.46 / 1.60
Space group	P 2 21 21
Cell size a, b, c (Å), α, β, γ (°)	56.06, 59.95, 77.66, 90, 90, 90
R / Rfree (%)	20.1 / 23.2

The binding sites of Fluorine atom in the Crystal Structure of Kpc-2 with Compound 2 (pdb code 7u8s). This binding sites where shown within 5.0 Angstroms radius around Fluorine atom.
In total only one binding site of Fluorine was determined in the Crystal Structure of Kpc-2 with Compound 2, PDB code: 7u8s:

Fluorine binding site 1 out of 1 in the Crystal Structure of Kpc-2 with Compound 2


Mono view


Stereo pair view

A full contact list of Fluorine with other atoms in the F binding site number 1 of Crystal Structure of Kpc-2 with Compound 2 within 5.0Å range: probe atom residue distance (Å) B Occ A:F301 b:58.9 occ:0.79 F A:LW0301 0.0 58.9 0.8 C13 A:LW0301 1.4 56.6 0.8 C12 A:LW0301 2.4 54.7 0.8 C14 A:LW0301 2.4 57.1 0.8 C11 A:LW0301 3.6 50.3 0.8 C15 A:LW0301 3.7 59.6 0.8 C16 A:LW0301 4.2 54.0 0.8 CB A:PRO104 4.8 32.9 1.0 C A:LW0301 4.8 43.3 0.8 CD1 A:LEU167 4.9 30.2 1.0

K.Defrees, E.M.Cambeis, Y.Chen, A.R.Renslo. Probing the Binding Hot Spots of Kpc-2 Carbapenemase Using Reversible Tetrazole-Based Inhibitors To Be Published.