Fluorine in PDB 7xz6: GPR119-Gs-APD668 Complex

The binding sites of Fluorine atom in the GPR119-Gs-APD668 Complex (pdb code 7xz6). This binding sites where shown within 5.0 Angstroms radius around Fluorine atom.
In total only one binding site of Fluorine was determined in the GPR119-Gs-APD668 Complex, PDB code: 7xz6:

Fluorine binding site 1 out of 1 in the GPR119-Gs-APD668 Complex


Mono view


Stereo pair view

A full contact list of Fluorine with other atoms in the F binding site number 1 of GPR119-Gs-APD668 Complex within 5.0Å range: probe atom residue distance (Å) B Occ R:F401 b:35.6 occ:1.00 F1 R:I7J401 0.0 35.6 1.0 C16 R:I7J401 1.3 35.6 1.0 C17 R:I7J401 2.4 35.6 1.0 C15 R:I7J401 2.4 35.6 1.0 H8 R:I7J401 2.5 35.6 1.0 HG13 R:VAL85 2.6 35.4 1.0 N3 R:I7J401 2.8 35.6 1.0 N5 R:I7J401 2.8 35.6 1.0 HB R:VAL85 2.9 35.4 1.0 HD1 R:PHE157 2.9 40.9 1.0 C12 R:I7J401 3.0 35.6 1.0 CG1 R:VAL85 3.3 35.4 1.0 HG12 R:VAL85 3.5 35.4 1.0 CD1 R:PHE157 3.6 40.9 1.0 CB R:VAL85 3.6 35.4 1.0 C20 R:I7J401 3.6 35.6 1.0 HE1 R:TRP265 3.6 37.1 1.0 HB2 R:PHE157 3.7 40.9 1.0 C18 R:I7J401 3.7 35.6 1.0 HG1 R:THR86 3.7 34.8 1.0 HA R:MET82 3.9 42.4 1.0 C11 R:I7J401 4.0 35.6 1.0 O R:MET82 4.0 42.4 1.0 N4 R:I7J401 4.0 35.6 1.0 C19 R:I7J401 4.1 35.6 1.0 OG1 R:THR86 4.1 34.8 1.0 NE1 R:TRP265 4.1 37.1 1.0 SD R:MET82 4.1 42.4 1.0 HG22 R:VAL85 4.1 35.4 1.0 HG11 R:VAL85 4.1 35.4 1.0 HE1 R:PHE157 4.1 40.9 1.0 CE1 R:PHE157 4.2 40.9 1.0 HZ2 R:TRP265 4.2 37.1 1.0 H R:THR86 4.3 34.8 1.0 C13 R:I7J401 4.3 35.6 1.0 CG R:PHE157 4.3 40.9 1.0 H16 R:I7J401 4.4 35.6 1.0 HB3 R:MET82 4.4 42.4 1.0 N R:THR86 4.4 34.8 1.0 CB R:PHE157 4.5 40.9 1.0 CG2 R:VAL85 4.5 35.4 1.0 H9 R:I7J401 4.5 35.6 1.0 CE2 R:TRP265 4.6 37.1 1.0 HD13 R:LEU61 4.6 41.5 1.0 CZ2 R:TRP265 4.6 37.1 1.0 CA R:MET82 4.6 42.4 1.0 C R:VAL85 4.7 35.4 1.0 C14 R:I7J401 4.7 35.6 1.0 CA R:VAL85 4.7 35.4 1.0 HA R:THR86 4.7 34.8 1.0 C R:MET82 4.7 42.4 1.0 CB R:MET82 4.9 42.4 1.0 HG23 R:VAL85 4.9 35.4 1.0 CD1 R:TRP265 4.9 37.1 1.0

P.Xu, S.Huang, S.Guo, Y.Yun, X.Cheng, X.He, P.Cai, Y.Lan, H.Zhou, H.Jiang, Y.Jiang, X.Xie, H.E.Xu. Structural Identification of Lysophosphatidylcholines As Activating Ligands For Orphan Receptor GPR119. Nat.Struct.Mol.Biol. V. 29 863 2022.
ISSN: ESSN 1545-9985
PubMed: 35970999
DOI: 10.1038/S41594-022-00816-5