Fluorine in PDB 8gut: Cryo-Em Structure of Lei-CB2-Gi Complex

The binding sites of Fluorine atom in the Cryo-Em Structure of Lei-CB2-Gi Complex (pdb code 8gut). This binding sites where shown within 5.0 Angstroms radius around Fluorine atom.
In total only one binding site of Fluorine was determined in the Cryo-Em Structure of Lei-CB2-Gi Complex, PDB code: 8gut:

Fluorine binding site 1 out of 1 in the Cryo-Em Structure of Lei-CB2-Gi Complex


Mono view


Stereo pair view

A full contact list of Fluorine with other atoms in the F binding site number 1 of Cryo-Em Structure of Lei-CB2-Gi Complex within 5.0Å range: probe atom residue distance (Å) B Occ R:F401 b:76.9 occ:1.00 F1 R:KO8401 0.0 76.9 1.0 C18 R:KO8401 1.4 76.9 1.0 C17 R:KO8401 2.4 76.9 1.0 C19 R:KO8401 2.4 76.9 1.0 C20 R:KO8401 2.8 76.9 1.0 CH2 R:TRP258 3.0 51.1 1.0 CZ3 R:TRP258 3.0 51.3 1.0 CH2 R:TRP194 3.2 63.9 1.0 CD2 R:PHE117 3.5 45.4 1.0 CB R:PHE117 3.6 44.4 1.0 N3 R:KO8401 3.6 76.9 1.0 CZ2 R:TRP194 3.6 61.7 1.0 C16 R:KO8401 3.6 76.9 1.0 CG R:PHE117 3.9 46.6 1.0 C8 R:KO8401 4.1 76.9 1.0 CZ3 R:TRP194 4.2 60.5 1.0 N4 R:KO8401 4.3 76.9 1.0 CZ2 R:TRP258 4.3 50.4 1.0 CE3 R:TRP258 4.4 47.6 1.0 CE2 R:PHE117 4.5 49.1 1.0 CE2 R:TRP194 4.9 54.8 1.0 C22 R:KO8401 5.0 76.9 1.0

X.Li, H.Chang, J.Bouma, L.V.De Paus, P.Mukhopadhyay, J.Paloczi, M.Mustafa, C.Van Der Horst, S.S.Kumar, L.Wu, Y.Yu, R.J.B.H.N.Van Den Berg, A.P.A.Janssen, A.Lichtman, Z.J.Liu, P.Pacher, M.Van Der Stelt, L.H.Heitman, T.Hua. Structural Basis of Selective Cannabinoid Cb 2 Receptor Activation. Nat Commun V. 14 1447 2023.
ISSN: ESSN 2041-1723
PubMed: 36922494
DOI: 10.1038/S41467-023-37112-9