Fluorine in PDB 8jn8: Crystal Structure of C-Src in Complex with Covalent Inhibitor Dc-Srci- 6668

All present enzymatic activity of Crystal Structure of C-Src in Complex with Covalent Inhibitor Dc-Srci- 6668:
2.7.10.2;

The structure of Crystal Structure of C-Src in Complex with Covalent Inhibitor Dc-Srci- 6668, PDB code: 8jn8 was solved by H.M.Zhang, C.Luo, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	46.15 / 1.90
Space group	P 21 21 21
Cell size a, b, c (Å), α, β, γ (°)	51.189, 82.91, 106.623, 90, 90, 90
R / Rfree (%)	21 / 25.4

The binding sites of Fluorine atom in the Crystal Structure of C-Src in Complex with Covalent Inhibitor Dc-Srci- 6668 (pdb code 8jn8). This binding sites where shown within 5.0 Angstroms radius around Fluorine atom.
In total only one binding site of Fluorine was determined in the Crystal Structure of C-Src in Complex with Covalent Inhibitor Dc-Srci- 6668, PDB code: 8jn8:

Fluorine binding site 1 out of 1 in the Crystal Structure of C-Src in Complex with Covalent Inhibitor Dc-Srci- 6668


Mono view


Stereo pair view

A full contact list of Fluorine with other atoms in the F binding site number 1 of Crystal Structure of C-Src in Complex with Covalent Inhibitor Dc-Srci- 6668 within 5.0Å range: probe atom residue distance (Å) B Occ A:F601 b:33.8 occ:1.00 F21 A:JA6601 0.0 33.8 1.0 C12 A:JA6601 1.4 28.3 1.0 C11 A:JA6601 2.5 29.7 1.0 C13 A:JA6601 2.5 30.6 1.0 O A:HOH815 2.9 11.7 1.0 CB A:LEU410 3.1 18.4 1.0 O A:ASP407 3.1 17.7 1.0 N A:ALA411 3.3 18.1 1.0 CB A:ASP407 3.6 18.9 1.0 C A:LEU410 3.8 18.5 1.0 CA A:LEU410 3.9 18.1 1.0 C10 A:JA6601 3.9 37.4 1.0 C14 A:JA6601 3.9 37.5 1.0 CD2 A:LEU410 3.9 23.7 1.0 CA A:ALA411 4.0 19.9 1.0 CG A:LEU410 4.0 28.4 1.0 N A:LEU410 4.1 20.2 1.0 C A:ASP407 4.1 16.5 1.0 CB A:ALA411 4.1 19.8 1.0 CA A:ASP407 4.4 19.5 1.0 CG A:ASP407 4.4 22.1 1.0 C9 A:JA6601 4.4 38.5 1.0 OD2 A:ASP407 4.7 27.1 1.0 O A:LEU410 4.7 22.4 1.0 CB A:ASP389 4.8 15.0 1.0 OD2 A:ASP389 4.9 20.4 1.0

H.M.Zhang, C.Luo. The Crystal Structure of C-Src in Complex with Covalent Inhibitor Dc-Srci-6668 To Be Published.