Atomistry » Fluorine » PDB 8smc-8t4v » 8szh
Atomistry »
  Fluorine »
    PDB 8smc-8t4v »
      8szh »

Fluorine in PDB 8szh: Cryo-Em Structure of Cinacalcet-Bound Human Calcium-Sensing Receptor Casr-Gi Complex in Lipid Nanodiscs

Other elements in 8szh:

The structure of Cryo-Em Structure of Cinacalcet-Bound Human Calcium-Sensing Receptor Casr-Gi Complex in Lipid Nanodiscs also contains other interesting chemical elements:

Calcium (Ca) 4 atoms

Fluorine Binding Sites:

The binding sites of Fluorine atom in the Cryo-Em Structure of Cinacalcet-Bound Human Calcium-Sensing Receptor Casr-Gi Complex in Lipid Nanodiscs (pdb code 8szh). This binding sites where shown within 5.0 Angstroms radius around Fluorine atom.
In total 6 binding sites of Fluorine where determined in the Cryo-Em Structure of Cinacalcet-Bound Human Calcium-Sensing Receptor Casr-Gi Complex in Lipid Nanodiscs, PDB code: 8szh:
Jump to Fluorine binding site number: 1; 2; 3; 4; 5; 6;

Fluorine binding site 1 out of 6 in 8szh

Go back to Fluorine Binding Sites List in 8szh
Fluorine binding site 1 out of 6 in the Cryo-Em Structure of Cinacalcet-Bound Human Calcium-Sensing Receptor Casr-Gi Complex in Lipid Nanodiscs


Mono view


Stereo pair view

A full contact list of Fluorine with other atoms in the F binding site number 1 of Cryo-Em Structure of Cinacalcet-Bound Human Calcium-Sensing Receptor Casr-Gi Complex in Lipid Nanodiscs within 5.0Å range:
probe atom residue distance (Å) B Occ
A:F901

b:52.3
occ:1.00
 F1 A:YP4901 0.0 52.3 1.0
C12 A:YP4901 1.4 50.7 1.0
F2 A:YP4901 2.2 51.5 1.0
F3 A:YP4901 2.2 51.9 1.0
C8 A:YP4901 2.4 46.2 1.0
C7 A:YP4901 2.7 48.0 1.0
CG2 A:ILE777 3.3 40.4 1.0
C9 A:YP4901 3.6 43.0 1.0
C6 A:YP4901 4.1 51.1 1.0
CE2 A:YP4901 4.3 46.1 1.0
CG1 A:ILE777 4.4 35.8 1.0
CB A:ILE777 4.5 36.8 1.0
CD1 A:ILE777 4.6 37.1 1.0
CZ A:YP4901 4.6 46.3 1.0
O A:TRP818 4.6 48.8 1.0
C10 A:YP4901 4.7 45.9 1.0
C11 A:YP4901 4.9 48.3 1.0
CD2 A:YP4901 5.0 45.9 1.0

Fluorine binding site 2 out of 6 in 8szh

Go back to Fluorine Binding Sites List in 8szh
Fluorine binding site 2 out of 6 in the Cryo-Em Structure of Cinacalcet-Bound Human Calcium-Sensing Receptor Casr-Gi Complex in Lipid Nanodiscs


Mono view


Stereo pair view

A full contact list of Fluorine with other atoms in the F binding site number 2 of Cryo-Em Structure of Cinacalcet-Bound Human Calcium-Sensing Receptor Casr-Gi Complex in Lipid Nanodiscs within 5.0Å range:
probe atom residue distance (Å) B Occ
A:F901

b:51.5
occ:1.00
 F2 A:YP4901 0.0 51.5 1.0
C12 A:YP4901 1.4 50.7 1.0
F1 A:YP4901 2.2 52.3 1.0
F3 A:YP4901 2.2 51.9 1.0
C8 A:YP4901 2.4 46.2 1.0
O A:TRP818 2.5 48.8 1.0
C9 A:YP4901 2.8 43.0 1.0
C A:TRP818 3.4 40.9 1.0
C7 A:YP4901 3.6 48.0 1.0
CB A:TRP818 3.8 38.2 1.0
C10 A:YP4901 4.1 45.9 1.0
CA A:TRP818 4.2 38.2 1.0
N A:ILE819 4.3 37.3 1.0
CG1 A:ILE822 4.4 42.0 1.0
CD1 A:ILE822 4.5 43.5 1.0
CA A:ILE819 4.5 36.4 1.0
CE3 A:TRP818 4.6 42.3 1.0
C6 A:YP4901 4.7 51.1 1.0
CG A:TRP818 4.7 40.3 1.0
C11 A:YP4901 4.9 48.3 1.0
CG1 A:ILE819 4.9 35.8 1.0
CD2 A:TRP818 5.0 41.8 1.0

Fluorine binding site 3 out of 6 in 8szh

Go back to Fluorine Binding Sites List in 8szh
Fluorine binding site 3 out of 6 in the Cryo-Em Structure of Cinacalcet-Bound Human Calcium-Sensing Receptor Casr-Gi Complex in Lipid Nanodiscs


Mono view


Stereo pair view

A full contact list of Fluorine with other atoms in the F binding site number 3 of Cryo-Em Structure of Cinacalcet-Bound Human Calcium-Sensing Receptor Casr-Gi Complex in Lipid Nanodiscs within 5.0Å range:
probe atom residue distance (Å) B Occ
A:F901

b:51.9
occ:1.00
 F3 A:YP4901 0.0 51.9 1.0
C12 A:YP4901 1.4 50.7 1.0
F2 A:YP4901 2.2 51.5 1.0
F1 A:YP4901 2.2 52.3 1.0
C8 A:YP4901 2.4 46.2 1.0
C9 A:YP4901 3.2 43.0 1.0
C7 A:YP4901 3.2 48.0 1.0
CD1 A:ILE822 4.1 43.5 1.0
CG1 A:ILE822 4.2 42.0 1.0
O A:TRP818 4.4 48.8 1.0
C10 A:YP4901 4.4 45.9 1.0
C6 A:YP4901 4.4 51.1 1.0
CG2 A:ILE777 4.6 40.4 1.0
C11 A:YP4901 4.9 48.3 1.0

Fluorine binding site 4 out of 6 in 8szh

Go back to Fluorine Binding Sites List in 8szh
Fluorine binding site 4 out of 6 in the Cryo-Em Structure of Cinacalcet-Bound Human Calcium-Sensing Receptor Casr-Gi Complex in Lipid Nanodiscs


Mono view


Stereo pair view

A full contact list of Fluorine with other atoms in the F binding site number 4 of Cryo-Em Structure of Cinacalcet-Bound Human Calcium-Sensing Receptor Casr-Gi Complex in Lipid Nanodiscs within 5.0Å range:
probe atom residue distance (Å) B Occ
B:F1402

b:52.3
occ:1.00
 F1 B:YP41402 0.0 52.3 1.0
C12 B:YP41402 1.4 53.5 1.0
F2 B:YP41402 2.2 51.8 1.0
F3 B:YP41402 2.2 55.4 1.0
C8 B:YP41402 2.4 49.5 1.0
C7 B:YP41402 2.9 47.6 1.0
C9 B:YP41402 3.5 48.5 1.0
C6 B:YP41402 4.2 50.1 1.0
C18 B:PCW1403 4.4 55.1 1.0
CD1 B:ILE777 4.5 44.0 1.0
CD2 B:LEU770 4.6 62.8 1.0
C10 B:YP41402 4.6 50.2 1.0
CD2 B:LEU773 4.8 49.0 1.0
CG B:LEU773 4.8 48.7 1.0
C11 B:YP41402 4.9 50.8 1.0
C16 B:PCW1403 5.0 52.4 1.0

Fluorine binding site 5 out of 6 in 8szh

Go back to Fluorine Binding Sites List in 8szh
Fluorine binding site 5 out of 6 in the Cryo-Em Structure of Cinacalcet-Bound Human Calcium-Sensing Receptor Casr-Gi Complex in Lipid Nanodiscs


Mono view


Stereo pair view

A full contact list of Fluorine with other atoms in the F binding site number 5 of Cryo-Em Structure of Cinacalcet-Bound Human Calcium-Sensing Receptor Casr-Gi Complex in Lipid Nanodiscs within 5.0Å range:
probe atom residue distance (Å) B Occ
B:F1402

b:51.8
occ:1.00
 F2 B:YP41402 0.0 51.8 1.0
C12 B:YP41402 1.4 53.5 1.0
F1 B:YP41402 2.2 52.3 1.0
F3 B:YP41402 2.2 55.4 1.0
C8 B:YP41402 2.4 49.5 1.0
C9 B:YP41402 2.7 48.5 1.0
C7 B:YP41402 3.6 47.6 1.0
CD2 B:LEU770 3.7 62.8 1.0
CD1 B:LEU770 3.9 63.0 1.0
C10 B:YP41402 4.1 50.2 1.0
CG B:LEU770 4.3 63.2 1.0
C6 B:YP41402 4.8 50.1 1.0
CB B:LEU770 4.8 62.6 1.0
C11 B:YP41402 4.9 50.8 1.0

Fluorine binding site 6 out of 6 in 8szh

Go back to Fluorine Binding Sites List in 8szh
Fluorine binding site 6 out of 6 in the Cryo-Em Structure of Cinacalcet-Bound Human Calcium-Sensing Receptor Casr-Gi Complex in Lipid Nanodiscs


Mono view


Stereo pair view

A full contact list of Fluorine with other atoms in the F binding site number 6 of Cryo-Em Structure of Cinacalcet-Bound Human Calcium-Sensing Receptor Casr-Gi Complex in Lipid Nanodiscs within 5.0Å range:
probe atom residue distance (Å) B Occ
B:F1402

b:55.4
occ:1.00
 F3 B:YP41402 0.0 55.4 1.0
C12 B:YP41402 1.4 53.5 1.0
F2 B:YP41402 2.2 51.8 1.0
F1 B:YP41402 2.2 52.3 1.0
C8 B:YP41402 2.4 49.5 1.0
C7 B:YP41402 3.0 47.6 1.0
C16 B:PCW1403 3.3 52.4 1.0
C9 B:YP41402 3.4 48.5 1.0
C14 B:PCW1403 3.6 52.9 1.0
C17 B:PCW1403 3.6 54.5 1.0
C18 B:PCW1403 3.7 55.1 1.0
C15 B:PCW1403 4.0 52.5 1.0
C6 B:YP41402 4.3 50.1 1.0
C10 B:YP41402 4.6 50.2 1.0
C19 B:PCW1403 4.8 54.5 1.0
C13 B:PCW1403 4.8 54.9 1.0
C11 B:YP41402 4.9 50.8 1.0
C12 B:PCW1403 5.0 56.5 1.0

Reference:

F.He, C.Wu, Y.Gao, G.Skiniotis. Allosteric Modulation and G-Protein Selectivity of the CA2+-Sensing Receptor Nature 2024.
ISSN: ESSN 1476-4687
DOI: 10.1038/S41586-024-07055-2
Page generated: Wed Jul 16 08:23:01 2025

Last articles

Fe in 2YXO
Fe in 2YRS
Fe in 2YXC
Fe in 2YNM
Fe in 2YVJ
Fe in 2YP1
Fe in 2YU2
Fe in 2YU1
Fe in 2YQB
Fe in 2YOO
© Copyright 2008-2020 by atomistry.com
Home   |    Site Map   |    Copyright   |    Contact us   |    Privacy