Fluorine in PDB 8tyq: Structure of the C-Terminal Half of LRRK2 Bound to Gzd-824 (G2019S Mutant)

The binding sites of Fluorine atom in the Structure of the C-Terminal Half of LRRK2 Bound to Gzd-824 (G2019S Mutant) (pdb code 8tyq). This binding sites where shown within 5.0 Angstroms radius around Fluorine atom.
In total 3 binding sites of Fluorine where determined in the Structure of the C-Terminal Half of LRRK2 Bound to Gzd-824 (G2019S Mutant), PDB code: 8tyq:
Jump to Fluorine binding site number: 1; 2; 3;

Fluorine binding site 1 out of 3 in the Structure of the C-Terminal Half of LRRK2 Bound to Gzd-824 (G2019S Mutant)


Mono view


Stereo pair view

A full contact list of Fluorine with other atoms in the F binding site number 1 of Structure of the C-Terminal Half of LRRK2 Bound to Gzd-824 (G2019S Mutant) within 5.0Å range: probe atom residue distance (Å) B Occ A:F2601 b:15.4 occ:1.00 F26 A:T3X2601 0.0 15.4 1.0 C25 A:T3X2601 1.3 8.8 1.0 F27 A:T3X2601 2.2 6.6 1.0 F28 A:T3X2601 2.2 29.1 1.0 C13 A:T3X2601 2.4 5.2 1.0 CE1 A:TYR1992 2.8 24.1 1.0 C14 A:T3X2601 3.1 9.7 1.0 C17 A:T3X2601 3.2 12.7 1.0 CD1 A:TYR1992 3.3 23.8 1.0 C12 A:T3X2601 3.3 8.6 1.0 C23 A:T3X2601 3.5 11.7 1.0 N18 A:T3X2601 3.6 13.5 1.0 C A:ALA2016 3.7 27.9 1.0 CZ A:TYR1992 3.9 22.9 1.0 CB A:ASP2017 3.9 18.6 1.0 O A:ALA2016 4.0 31.7 1.0 CA A:ALA2016 4.0 22.1 1.0 N A:ASP2017 4.0 28.6 1.0 CG1 A:ILE2015 4.0 25.9 1.0 O A:ILE2015 4.1 21.7 1.0 N A:ALA2016 4.2 21.9 1.0 OH A:TYR1992 4.2 29.5 1.0 C A:ILE2015 4.3 21.7 1.0 C15 A:T3X2601 4.4 7.6 1.0 CD1 A:ILE2015 4.5 24.3 1.0 C11 A:T3X2601 4.5 11.9 1.0 C22 A:T3X2601 4.6 7.1 1.0 CA A:ASP2017 4.6 16.9 1.0 CG A:TYR1992 4.6 20.3 1.0 CD1 A:LEU1985 4.6 18.6 1.0 CD2 A:LEU1932 4.8 16.2 1.0 C19 A:T3X2601 4.9 14.7 1.0 C16 A:T3X2601 4.9 5.7 1.0 CB A:ILE2015 4.9 25.8 1.0

Fluorine binding site 2 out of 3 in the Structure of the C-Terminal Half of LRRK2 Bound to Gzd-824 (G2019S Mutant)


Mono view


Stereo pair view

A full contact list of Fluorine with other atoms in the F binding site number 2 of Structure of the C-Terminal Half of LRRK2 Bound to Gzd-824 (G2019S Mutant) within 5.0Å range: probe atom residue distance (Å) B Occ A:F2601 b:6.6 occ:1.00 F27 A:T3X2601 0.0 6.6 1.0 C25 A:T3X2601 1.3 8.8 1.0 F28 A:T3X2601 2.2 29.1 1.0 F26 A:T3X2601 2.2 15.4 1.0 C13 A:T3X2601 2.3 5.2 1.0 C12 A:T3X2601 2.6 8.6 1.0 O A:ILE2015 2.7 21.7 1.0 CA A:ALA2016 3.3 22.1 1.0 C A:ILE2015 3.4 21.7 1.0 CG2 A:ILE1933 3.7 26.8 1.0 C14 A:T3X2601 3.7 9.7 1.0 N A:ALA2016 3.7 21.9 1.0 C A:ALA2016 3.9 27.9 1.0 C11 A:T3X2601 4.0 11.9 1.0 CG1 A:ILE2015 4.0 25.9 1.0 N A:ASP2017 4.1 28.6 1.0 O09 A:T3X2601 4.1 9.8 1.0 N A:ILE1933 4.2 14.3 1.0 CD2 A:LEU1932 4.3 16.2 1.0 C17 A:T3X2601 4.3 12.7 1.0 CB A:ALA2016 4.5 19.8 1.0 O A:ALA2016 4.6 31.7 1.0 CA A:ILE2015 4.7 25.2 1.0 CB A:ILE1933 4.7 22.4 1.0 CA A:LEU1932 4.7 23.8 1.0 C15 A:T3X2601 4.7 7.6 1.0 CB A:LEU1932 4.8 23.6 1.0 C08 A:T3X2601 4.8 5.7 1.0 N10 A:T3X2601 4.8 11.8 1.0 CE1 A:TYR1992 4.8 24.1 1.0 C16 A:T3X2601 4.8 5.7 1.0 CB A:ILE2015 4.9 25.8 1.0 C A:LEU1932 4.9 21.4 1.0 CD1 A:ILE2015 4.9 24.3 1.0

Fluorine binding site 3 out of 3 in the Structure of the C-Terminal Half of LRRK2 Bound to Gzd-824 (G2019S Mutant)


Mono view


Stereo pair view

A full contact list of Fluorine with other atoms in the F binding site number 3 of Structure of the C-Terminal Half of LRRK2 Bound to Gzd-824 (G2019S Mutant) within 5.0Å range: probe atom residue distance (Å) B Occ A:F2601 b:29.1 occ:1.00 F28 A:T3X2601 0.0 29.1 1.0 C25 A:T3X2601 1.3 8.8 1.0 F27 A:T3X2601 2.2 6.6 1.0 F26 A:T3X2601 2.2 15.4 1.0 C13 A:T3X2601 2.3 5.2 1.0 C17 A:T3X2601 2.8 12.7 1.0 C14 A:T3X2601 2.9 9.7 1.0 CD2 A:LEU1932 3.4 16.2 1.0 C12 A:T3X2601 3.4 8.6 1.0 N18 A:T3X2601 3.8 13.5 1.0 CD1 A:LEU1927 4.0 22.0 1.0 C15 A:T3X2601 4.2 7.6 1.0 CD2 A:LEU1985 4.3 25.4 1.0 C23 A:T3X2601 4.4 11.7 1.0 O A:ILE2015 4.4 21.7 1.0 CG1 A:ILE2015 4.4 25.9 1.0 CD1 A:LEU1985 4.4 18.6 1.0 CG A:LEU1932 4.5 16.4 1.0 CB A:LEU1932 4.6 23.6 1.0 C11 A:T3X2601 4.6 11.9 1.0 CD1 A:ILE2015 4.8 24.3 1.0 CE1 A:TYR1992 4.8 24.1 1.0 CG A:LEU1985 4.8 16.1 1.0 CD1 A:TYR1992 4.8 23.8 1.0 C19 A:T3X2601 4.9 14.7 1.0 C16 A:T3X2601 4.9 5.7 1.0 CD1 A:LEU1932 4.9 24.5 1.0

A.Villagran-Suarez, M.Sanz-Murillo, S.Mathea, J.Alegrio-Louro, S.Reck-Peterson, S.Knapp, A.E.Leschziner. Structure of the C-Terminal Half of LRRK2 Bound to Gzd-824 (G2019S Mutant) To Be Published.