Fluorine in PDB 8tzb: Structure of the C-Terminal Half of LRRK2 Bound to Gzd-824 (I2020T Mutant)

The binding sites of Fluorine atom in the Structure of the C-Terminal Half of LRRK2 Bound to Gzd-824 (I2020T Mutant) (pdb code 8tzb). This binding sites where shown within 5.0 Angstroms radius around Fluorine atom.
In total 3 binding sites of Fluorine where determined in the Structure of the C-Terminal Half of LRRK2 Bound to Gzd-824 (I2020T Mutant), PDB code: 8tzb:
Jump to Fluorine binding site number: 1; 2; 3;

Fluorine binding site 1 out of 3 in the Structure of the C-Terminal Half of LRRK2 Bound to Gzd-824 (I2020T Mutant)


Mono view


Stereo pair view

A full contact list of Fluorine with other atoms in the F binding site number 1 of Structure of the C-Terminal Half of LRRK2 Bound to Gzd-824 (I2020T Mutant) within 5.0Å range: probe atom residue distance (Å) B Occ A:F2601 b:14.3 occ:1.00 F26 A:T3X2601 0.0 14.3 1.0 C25 A:T3X2601 1.4 12.8 1.0 F27 A:T3X2601 2.2 19.9 1.0 F28 A:T3X2601 2.2 33.3 1.0 C13 A:T3X2601 2.4 0.0 1.0 C14 A:T3X2601 3.0 15.6 1.0 CE2 A:TYR1992 3.0 14.5 1.0 C17 A:T3X2601 3.0 23.0 1.0 C23 A:T3X2601 3.2 19.3 1.0 CD2 A:TYR1992 3.5 12.6 1.0 C12 A:T3X2601 3.5 15.9 1.0 N18 A:T3X2601 3.7 28.7 1.0 CB A:ASP2017 4.1 19.5 1.0 CZ A:TYR1992 4.2 12.9 1.0 CD1 A:LEU1985 4.2 2.6 1.0 C15 A:T3X2601 4.3 19.6 1.0 C22 A:T3X2601 4.5 9.5 1.0 OH A:TYR1992 4.5 25.9 1.0 CG2 A:ILE2015 4.6 22.2 1.0 C19 A:T3X2601 4.6 11.8 1.0 CD2 A:LEU1932 4.6 21.8 1.0 C11 A:T3X2601 4.7 14.6 1.0 C A:ALA2016 4.7 15.2 1.0 N A:ASP2017 4.7 18.0 1.0 O A:ILE2015 4.7 16.4 1.0 CB A:ILE2015 4.8 16.1 1.0 CD2 A:LEU1985 4.8 4.8 1.0 CG A:TYR1992 4.8 13.7 1.0 C A:ILE2015 4.9 18.4 1.0 O A:ALA2016 5.0 21.2 1.0 C16 A:T3X2601 5.0 12.9 1.0

Fluorine binding site 2 out of 3 in the Structure of the C-Terminal Half of LRRK2 Bound to Gzd-824 (I2020T Mutant)


Mono view


Stereo pair view

A full contact list of Fluorine with other atoms in the F binding site number 2 of Structure of the C-Terminal Half of LRRK2 Bound to Gzd-824 (I2020T Mutant) within 5.0Å range: probe atom residue distance (Å) B Occ A:F2601 b:19.9 occ:1.00 F27 A:T3X2601 0.0 19.9 1.0 C25 A:T3X2601 1.4 12.8 1.0 F26 A:T3X2601 2.2 14.3 1.0 F28 A:T3X2601 2.2 33.3 1.0 C13 A:T3X2601 2.4 0.0 1.0 C12 A:T3X2601 2.7 15.9 1.0 O A:ILE2015 2.8 16.4 1.0 C A:ILE2015 3.4 18.4 1.0 C14 A:T3X2601 3.7 15.6 1.0 CA A:ALA2016 3.8 7.5 1.0 N A:ALA2016 3.8 12.9 1.0 CD2 A:LEU1932 4.0 21.8 1.0 C11 A:T3X2601 4.0 14.6 1.0 CB A:ILE2015 4.1 16.1 1.0 C A:ALA2016 4.1 15.2 1.0 N A:ASP2017 4.2 18.0 1.0 CA A:ILE2015 4.4 13.8 1.0 CG2 A:ILE1933 4.4 14.4 1.0 O09 A:T3X2601 4.4 18.2 1.0 C17 A:T3X2601 4.4 23.0 1.0 CG2 A:ILE2015 4.5 22.2 1.0 CE2 A:TYR1992 4.6 14.5 1.0 CB A:ASP2017 4.8 19.5 1.0 O A:ALA2016 4.8 21.2 1.0 C15 A:T3X2601 4.8 19.6 1.0 N A:ILE1933 4.8 18.2 1.0 CB A:LEU1932 4.9 11.0 1.0 C16 A:T3X2601 4.9 12.9 1.0 N10 A:T3X2601 4.9 8.1 1.0 CG A:LEU1932 5.0 11.8 1.0

Fluorine binding site 3 out of 3 in the Structure of the C-Terminal Half of LRRK2 Bound to Gzd-824 (I2020T Mutant)


Mono view


Stereo pair view

A full contact list of Fluorine with other atoms in the F binding site number 3 of Structure of the C-Terminal Half of LRRK2 Bound to Gzd-824 (I2020T Mutant) within 5.0Å range: probe atom residue distance (Å) B Occ A:F2601 b:33.3 occ:1.00 F28 A:T3X2601 0.0 33.3 1.0 C25 A:T3X2601 1.4 12.8 1.0 F27 A:T3X2601 2.2 19.9 1.0 F26 A:T3X2601 2.2 14.3 1.0 C13 A:T3X2601 2.4 0.0 1.0 C14 A:T3X2601 3.0 15.6 1.0 C17 A:T3X2601 3.1 23.0 1.0 CD2 A:LEU1932 3.3 21.8 1.0 C12 A:T3X2601 3.4 15.9 1.0 CD1 A:LEU1927 3.6 17.2 1.0 CD1 A:LEU1932 3.9 9.1 1.0 CD2 A:LEU1985 4.0 4.8 1.0 CG A:LEU1932 4.1 11.8 1.0 C15 A:T3X2601 4.3 19.6 1.0 N18 A:T3X2601 4.4 28.7 1.0 CD1 A:LEU1985 4.4 2.6 1.0 CB A:LEU1932 4.4 11.0 1.0 C23 A:T3X2601 4.6 19.3 1.0 CG A:LEU1985 4.6 0.0 1.0 C11 A:T3X2601 4.6 14.6 1.0 O A:ILE2015 4.8 16.4 1.0 CG A:LEU1927 4.8 20.9 1.0 CB A:LEU1927 4.9 20.4 1.0 C16 A:T3X2601 5.0 12.9 1.0

A.Villagran-Suarez, M.Sanz-Murillo, J.Alegrio-Louro, A.Leschziner. Structure of the C-Terminal Half of LRRK2 Bound to Gzd-824 (I2020T Mutant) To Be Published.